Results 211 to 220 of about 83,539 (262)

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source

Serum macrophage migration inhibitory factor as a predictor of radiographic progression in ankylosing spondylitis: a retrospective cohort study. [PDF]

Clin Rheumatol
Gazar YAE, Ismail S, Ghanem S, Ghit MM, Azzam AI.   +4 more
europepmc   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Functionalizing biomaterials for osseointegration - microRNAs at the crossroads of bone formation and immune modulation. [PDF]

Bone Joint Res
Azari M, Della Bella E, Wildemann B.
europepmc   +1 more source

M2 type macrophages promote OSCC progress via conferring resistance to Erastin-induced ferroptosis. [PDF]

Sci Rep
Su C, Gu Z, Wang J, Xue Y, Song X, Yuan M, Ke H, Deng R.   +7 more
europepmc   +1 more source

New Immunological Insights into Bisphosphonate-Related Osteonecrosis of the Jaw: A Multidimensional Reappraisal from Molecular Switches to Clinical Phenotypes. [PDF]

Curr Issues Mol Biol
Li Y, Qin S, Wang J, Shan Z, Song J, Zhang H, Pan W, Zhu Z.   +7 more
europepmc   +1 more source

TGFBI in tumors and the tumor immune microenvironment: functional roles, mechanisms, and therapeutic targeting. [PDF]

Front Immunol
Li J, Zeng Y, Chen F, Hu J, Guo Z, Peng P.   +5 more
europepmc   +1 more source

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies. [PDF]

MedComm (2020)
Zhao Y, Xu W, Wang Y, Huang H, Su Y, Zhou L, Liu J, Guo J.   +7 more
europepmc   +1 more source

Ligand-dependent corepressor suppresses angiogenesis and macrophage infiltration in gliobl astoma microenvironment via MCP-1 down-regulation. [PDF]

BMC Biotechnol
Lin SK, Li TQ, Luo XL, Zhang YC, Qian JX, Huang SL, Yang M, Linghu KG, Dong J.   +8 more
europepmc   +1 more source