Results 121 to 130 of about 1,228,727 (302)

Exposure duration of ambient fine particulate matter determines the polarization of macrophages

open access: yesCentral European Journal of Immunology, 2023
Ambient fine particulate matter (FPM) promotes airway inflammation and aggravates respiratory and cardiovascular diseases. Macrophage polarization plays an essential role in FPM-induced inflammation and tissue repair.
Xiangru Li   +4 more
doaj   +1 more source

Evolutionary Aspects of Macrophages Polarization [PDF]

open access: yes, 2017
Macrophages constitute a heterogeneous population of myeloid cells that are essential for maintaining homeostasis and as a first line of innate responders controlling and organizing host defenses against pathogens. Monocyte-macrophage lineage cells are among the most functionally diverse and plastic cells of the immune system.
Kun Hyoe Rhoo   +2 more
openaire   +3 more sources

Implications of macrophage polarization in autoimmunity [PDF]

open access: yesImmunology, 2018
SummaryMacrophages are extremely heterogeneous and plastic cells with an important role not only in physiological conditions, but also during inflammation (both for initiation and resolution). In the early 1990s, two different phenotypes of macrophages were described: one of them called classically activated (or inflammatory) macrophages (M1) and the ...
Samanta C. Funes   +3 more
openaire   +3 more sources

Effects of Metabolism on Macrophage Polarization Under Different Disease Backgrounds

open access: yesFrontiers in Immunology, 2022
Macrophages are versatile immune cells associated with various diseases, and their phenotypes and functions change on the basis of the surrounding environments. Reprogramming of metabolism is required for the proper polarization of macrophages.
Jia-Xue Sun, Xiang-Hong Xu, Liping Jin
semanticscholar   +1 more source

Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis

open access: yesRespiratory Research
Acute lung injury (ALI) is one of the life-threatening complications of sepsis, and macrophage polarization plays a crucial role in the sepsis-associated ALI.
Wenhui Huang   +4 more
doaj   +1 more source

GRN Activates TNFR2 to Promote Macrophage M2 Polarization Aggravating Mycobacterium Tuberculosis Infection

open access: yesFrontiers in Bioscience-Landmark
Background: The polarization of macrophages plays a critical role in the immune response to infectious diseases, with M2 polarization shown to be particularly important in various pathological processes.
Bingling Zhang   +6 more
doaj   +1 more source

A lipid-structured mathematical model of atherosclerosis with macrophage proliferation [PDF]

open access: yesarXiv, 2022
We extend the lipid-structured model for atherosclerotic plaque development of Ford et al. (2019) to account for macrophage proliferation. Proliferation is modelled as a non-local decrease in the lipid structural variable that is similar to the treatment of cell division in size-structured models (e.g. Efendiev et al. (2018)).
arxiv  

Treating Macrophages with Anti-inflammatory Nanoparticles as a Strategy to Improve Muscle Repair [PDF]

open access: yes, 2019
The macrophage is an immune cell that is involved in host defense. More recent research, however, has revealed that they also play a central role in mediating the skeletal muscle regenerative process.
Yan, Derek
core   +1 more source

Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro. [PDF]

open access: yesPLoS ONE, 2015
The tuberculous granuloma is an elaborately organized structure and one of the main histological hallmarks of tuberculosis. Macrophages, which are important immunologic effector and antigen-presenting cells, are the main cell type found in the ...
Zikun Huang   +7 more
doaj   +1 more source

Effects of nanocrystalline hydroxyapatites on macrophage polarization [PDF]

open access: yesJournal of Materials Chemistry B, 2016
Nanocrystalline hydroxyapatites favour the macrophage polarization towards a M2 reparative phenotype, ensuring an appropriate response in the implantation site.
Linares, J.   +8 more
openaire   +4 more sources

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