Results 261 to 270 of about 166,541 (336)

Mechanism of sepsis regulation by ELANE via macrophage polarization. [PDF]

Sci Rep
Leng L, Yang Y, Zhang H, Peng W, Xiang X, Hu Y, Ma C.   +6 more
europepmc   +1 more source

Interleukin-4 regulates macrophage polarization via the MAPK signaling pathway to protect against atherosclerosis

, 2016
Xin Zhao, Y.N. Li, Yu Wang
openalex   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Global research trends on macrophage polarization in osteoarthritis: a bibliometric analysis. [PDF]

Front Immunol
Bamahel AS, Liu J, Zhang Z, Deng Y, Xue C, Sun X, Wu W, Bi S, Zubair N, Nie G, Xu H.   +10 more
europepmc   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

PPARα modulation of macrophage polarization and inflammatory signaling in mimic periodontitis. [PDF]

J Appl Oral Sci
Arthur HU, Chen YY.
europepmc   +1 more source

Inhibition of NADPH oxidase 2 enhances resistance to viral neuroinflammation by facilitating M1-polarization of macrophages at the extraneural tissues [PDF]

Jin‐Young Choi, Hee Won Byeon, Seong Ok Park, Erdenebileg Uyangaa, Koanhoi Kim, Seong Kug Eo   +5 more
openalex   +1 more source

Stress-induced macrophage polarization [PDF]

Nature Reviews Immunology, 2017
openaire   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Malaria pigment hemozoin drives M1 pro-inflammatory macrophage polarization in vitro. [PDF]

Sci Rep
Perego F, Parapini S, Calvo-Alvarez E, Dolci M, Delbue S, Ghezzi S, Vicenzi E, Poli G, Basilico N, D'Alessandro S.   +9 more
europepmc   +1 more source