Results 61 to 70 of about 1,228,727 (302)
The role of macrophage subtypes and exosomes in immunomodulation
Cellular & Molecular Biology Letters, 2022 Macrophages are influential members of the innate immune system that can be reversibly polarized by different microenvironment signals. Cell polarization leads to a wide range of features, involving the migration, development, and organization of the ...
Abdulwahab Teflischi Gharavi +3 more
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Metabolic-epigenetic regulation of macrophage polarization. [PDF]
, 2021 Tumor-associated macrophages polarized to an M2 phenotype (M2-TAMs) promote neo-angiogenesis, tumor-stromal matrix remodeling, and immuno-evasion, which, collectively, contribute to immunotherapeutic resistance and reduced cancer patient survival. Highly
Noe, Jordan T.
core +1 more source
The potential role of miRNA in regulating macrophage polarization
Heliyon, 2023 Macrophage polarization is a dynamic process determining the outcome of various physiological and pathological situations through inducing pro-inflammatory responses or resolving inflammation via exerting anti-inflammatory effects.
Shaho Khayati +5 more
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Macrophage Polarization: Learning to Manage It
International Journal of Molecular Sciences, 2022 To date, four reviews and seven experimental articles have been published in this Special Issue [...]
openaire +3 more sources
Macrophage autophagy in macrophage polarization, chronic inflammation and organ fibrosis
Frontiers in Immunology, 2022 As the essential regulators of organ fibrosis, macrophages undergo marked phenotypic and functional changes after organ injury. These changes in macrophage phenotype and function can result in maladaptive repair, causing chronic inflammation and the ...
Jun-Hao Wen +5 more
semanticscholar +1 more source
BMC Nephrology, 2020 Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Autoimmune thyroid disease (AITD), the most common autoimmune disease, includes Graves’ disease (GD) and Hashimoto’s thyroiditis (HT). Currently, the pathogenesis of AITD is not fully understood.
Tiantian Cai +8 more
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Metabolic Reprogramming Induces Macrophage Polarization in the Tumor Microenvironment
Frontiers in Immunology, 2022 Macrophages are one of the most important cells in the innate immune system, they are converted into two distinct subtypes with completely different molecular phenotypes and functional features under different stimuli of the microenvironment: M1 ...
Shilin Wang +3 more
semanticscholar +1 more source
Macrophage polarization and meta-inflammation [PDF]
Translational Research, 2018 Chronic overnutrition and obesity induces low-grade inflammation throughout the body. Termed "meta-inflammation," this chronic state of inflammation is mediated by macrophages located within the colon, liver, muscle, and adipose tissue. A sentinel orchestrator of immune activity and homeostasis, macrophages adopt variable states of activation as a ...
Chuan Li +5 more
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Stem cell research & therapeutics, 2022 Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a common cause of end-stage renal disease (ESRD). Mesenchymal stem cells (MSCs) possess potent anti-inflammatory and immunomodulatory properties, which render them an attractive ...
Yaqi Zhang +11 more
semanticscholar +1 more source