Results 41 to 50 of about 116,710 (303)
Orchestration of macrophage polarization
Blood, 2009 Abstract In this issue of Blood, Ishii and colleagues shed new, fresh light on molecular mechanisms underlying one form of macrophage activation.
A. Mantovani, M. Locati
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Macrophage Polarization is Deregulated in Haemophilia [PDF]
Thrombosis and Haemostasis, 2019 AbstractMacrophages make important contributions to inflammation and wound healing. We show here that macrophage polarization is deregulated in haemophilia in response to macrophage colony-stimulating factor (M-CSF) and partially in response to granulocyte-macrophage colony-stimulating factor (GM-CSF).
Knowles, Lynn M. +5 more
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BMC Nephrology, 2020 Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentiation and polarization of macrophages into pro-
Hewang Lee +4 more
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Macrophage Polarization in Inflammatory Diseases [PDF]
International Journal of Biological Sciences, 2014 Diversity and plasticity are two hallmarks of macrophages. M1 macrophages (classically activated macrophages) are pro-inflammatory and have a central role in host defense against infection, while M2 macrophages (alternatively activated macrophages) are associated with responses to anti-inflammatory reactions and tissue remodeling, and they represent ...
Liu, Yan-Cun +3 more
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The role of macrophage subtypes and exosomes in immunomodulation
Cellular & Molecular Biology Letters, 2022 Macrophages are influential members of the innate immune system that can be reversibly polarized by different microenvironment signals. Cell polarization leads to a wide range of features, involving the migration, development, and organization of the ...
Abdulwahab Teflischi Gharavi +3 more
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Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]
, 2012 Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Anders, Hans-Joachim, Weidenbusch, Marc
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Phagosome maturation in polarized macrophages [PDF]
Journal of Leukocyte Biology, 2014 ABSTRACTMacrophages are capable of assuming distinct, meta-stable, functional phenotypes in response to environmental cues—a process referred to as macrophage polarization. The identity and plasticity of polarized macrophage subsets as well as their functions in the maintenance of homeostasis and the progression of various pathologies have become areas
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Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity [PDF]
, 2011 Background: Arachidonic acid is metabolized through three major metabolic pathways, the cyclooxygenase, lipoxygenase and CYP450 enzyme systems. Unlike cyclooxygenase and lipoxygenases, the role of CYP450 epoxygenases in monocyte/macrophage-mediated ...
Bishop-Bailey, D +45 more
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Polarizing Macrophages In Vitro
, 2018 Macrophages are a heterogeneous population of innate myeloid cells involved in health and disease, which are the most functionally diverse cells of the hematopoietic system. The main functions of macrophages include responding to pathogens and modulating the adaptive immune response, induction and resolution of inflammation, tissue repair, and ...
Xuan, Huang +3 more
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Oral squamous cell carcinoma-derived exosomes promote M2 subtype macrophage polarization mediated by exosome-enclosed miR-29a-3p [PDF]
, 2019 Oral squamous cell carcinoma-derived exosomes promote M2 subtype macrophage polarization mediated by exosome-enclosed miR-29a-3p. Am J Physiol Cell Physiol 316: C731–C740, 2019.
Cai, J, Lin, N, He, W, Qiao, B, Gao, N
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