Results 21 to 30 of about 116,710 (303)
Acid Dentin Lysate Modulates Macrophage Polarization and Osteoclastogenesis In Vitro. [PDF]
, 2021 Dentin prepared from extracted teeth is used as autograft for alveolar bone augmentation. Graft consolidation involves the acid lysis of dentin thereby generating a characteristic paracrine environment. Acid lysate of dentin is mimicking this environment.
Gruber, Reinhard +7 more
core +1 more source
Metabolic Reprograming in Macrophage Polarization [PDF]
Frontiers in Immunology, 2014 Studying the metabolism of immune cells in recent years has emphasized the tight link existing between the metabolic state and the phenotype of these cells. Macrophages in particular are a good example of this phenomenon. Whether the macrophage obtains its energy through glycolysis or through oxidative metabolism can give rise to different phenotypes ...
Silvia Galván-Peña +1 more
openaire +3 more sources
Leishmaniasis: Immune Cells Crosstalk in Macrophage Polarization [PDF]
, 2023 Leishmaniasis is a complex infectious parasitic disease caused by protozoa of the genus Leishmania, belonging to a group of neglected tropical diseases. It establishes significant global health challenges, particularly in socio-economically disadvantaged
Tatjana S. L. Keesen +8 more
core +1 more source
Macrophage polarization and meta-inflammation [PDF]
Translational Research, 2018 Chronic overnutrition and obesity induces low-grade inflammation throughout the body. Termed "meta-inflammation," this chronic state of inflammation is mediated by macrophages located within the colon, liver, muscle, and adipose tissue. A sentinel orchestrator of immune activity and homeostasis, macrophages adopt variable states of activation as a ...
Chuan Li +5 more
openaire +2 more sources
Lithium silicate-based bioceramics promoting chondrocyte maturation by immunomodulating M2 macrophage polarization [PDF]
, 2020 Articular cartilage lesions occur frequently but unfortunately the damaged cartilage has a very limited intrinsic repair capacity. Since the cartilage damage can cause sterile inflammation, the effects of inflammation on cartilage repair should be well ...
Zhu, Yufang +5 more
core +1 more source
Phenotypic Polarization of Macrophages in Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013 Macrophages orchestrate the inflammatory response in inflamed tissues, and recent work indicates that these cells can alter their phenotypes and functions accordingly in response to changes in the microenvironment. Initial work in models of cardiovascular disease used immunologic markers to characterize macrophage phenotypes present in atherosclerotic ...
Norbert, Leitinger, Ira G, Schulman
openaire +2 more sources
Polarization and Repolarization of Macrophages
Journal of Clinical and Cellular Immunology, 2015 Macrophages can acquire distinct phenotypes and biological functions depending on the microenvironment and the metabolic state. Macrophages classically activated by IFN-γ and/or microbial products display an M1 phenotype characterized by high expression of interleukin (IL)-12, inducible nitric oxide synthase (iNOS) and TNF-α.
FRATERNALE, ALESSANDRA +2 more
openaire +2 more sources
Transcriptional Control of Macrophage Polarization [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013 Macrophages are key regulators of many organ systems, including innate and adaptive immunity, systemic metabolism, hematopoiesis, vasculogenesis, malignancy, and reproduction. The pleiotropic roles of macrophages are mirrored by similarly diverse cellular phenotypes.
Derin, Tugal +2 more
openaire +2 more sources
Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]
, 2010 Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M. +17 more
core +1 more source
Cell Death and Disease, 2023 Reprogramming of macrophages toward an M1 phenotype is a novel strategy to induce anticancer immunity. However, the regulatory mechanisms of M1 macrophage polarization and its functional roles in nasopharyngeal carcinoma (NPC) progression need to be ...
Huai Liu +7 more
doaj +1 more source