Results 101 to 110 of about 261,309 (244)

Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]

, 2010
Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M., Huitinga, I., Voehringer, David, Raes, G., van Eijk, Marco, Hoek, Robert M., Hamann, J., Huitinga, Inge, Koning, N., Brouwer, M.S., Raes, Geert, Pouwels, W., Voehringer, D., Koning, Nathalie, Van Eijk, M., Hoek, R.M., Pouwels, Walter, Hamann, Jörg   +17 more
core   +1 more source

DPICache: A Distributed Program Image Cache for Wireless Sensor Networks

, 2008
Wireless sensor networks, like other computing platforms, require software updates from time to time due to software bugs, new functionality, better understanding of the surrounding environment or new applications.
Martinez, Kirk, Ellul, Joshua
core   +2 more sources

The link between macrophage polarization and response to radiotherapy in cancers: mechanisms and therapeutic opportunities

Frontiers in Immunology
Macrophages, as central players in the tumor microenvironment (TME), exhibit remarkable plasticity, shifting between pro-inflammatory M1 and immunosuppressive M2 states. This polarization directly influences the response to radiotherapy in cancers. While
Zibing Zhao, Zhuangzhuang Zheng
doaj   +1 more source

Glycosaminoglycan-Induced Macrophage Reprogramming Orchestrates Pro-Regenerative Crosstalk with Fibroblasts

Macrophages and fibroblasts play central roles in coordinating inflammation and tissue repair, whilst dysregulation of macrophage-fibroblast crosstalk drives pathological outcomes such as chronic inflammation and fibrosis.
Arsalan Latif, Anna Kotowska, Qiran Du, Amir M. Ghaemmaghami, Kei F.C. Wong, Andrew Hook, Kimberly Mace, Karen Lawler, Reem A. AlRomaihi   +8 more
core   +1 more source

Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1

, 2017
Key PointsPlg and Pla induce macrophage reprogramming and promote resolution of acute inflammation. Plg and Pla enhance the efferocytic capacity of macrophages and override the prosurvival effect of LPS on neutrophils via annexin A1.
Miles, Lindsey A., Vago, Juliana P., Lirlândia P. Sousa, Garcia, Cristiana C., Sugimoto, Michelle A., Fernanda S. Carneiro, Alessandra C. Reis, Michelle A. Sugimoto, Bruno R. C. Costa, Mylena Maira O. Ortiz, Juliana P. Vago, Mauro M. Teixeira, Graziele Letícia N. Lima, Ortiz, Mylena Maira O., Sousa, Lirlândia P., Kátia M. Lima, Renata M. Rocha, Lindsey A. Miles, Ana Luíza C. Ribeiro, Denise A. Perez, Ribeiro, Ana Luíza C., Costa, Bruno R. C., Reis, Alessandra C., Pinho, Vanessa, Lima, Graziele Letícia N., Carmo, Aline A. F., Cristiana C. Garcia, Carneiro, Fernanda S., Aline A. F. Carmo, Lima, Kátia M., Rocha, Renata M., Perez, Denise A., Vanessa Pinho, Teixeira, Mauro M.   +33 more
core   +1 more source

Stromal Control of Macrophage Dysfunction in Oral Squamous Cell Carcinoma: Mechanistic Barriers and Therapeutic Strategies for Durable Immune Reprogramming

Objective: Oral squamous cell carcinoma (OSCC) is characterized by a highly complex and immunosuppressive tumor microenvironment (TME) that significantly limits the efficacy and durability of immune-based therapies.
Taniya Mary Martin, Meenakshi Sundaram Kishore Kumar, Jabir Padathpeedika Khalid   +2 more
core   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Serum-Derived Macrophage-Activating Factor Exhibits Anti-Tumor Activity via M2-to-M1 Macrophage Reprogramming

Many anti-tumor effects of group-specific component-derived macrophage-activating factors (GcMAFs) have been reported; however, the specific mechanisms remain unclear.
Aya Kobayashi, Rei Takara, Yusei Shinohara, Yoshihiro Uto, Hina Shirakata, Tsuyoshi Takara, Shinobu Ambai   +6 more
core   +1 more source

Branched-chain amino acid metabolism and macrophage polarization: potential regulatory nodes and therapeutic targets in diabetes-associated metabolic inflammation

Frontiers in Cellular and Infection Microbiology
T2DM is characterized by chronic low-grade metabolic inflammation, and imbalanced macrophage polarization is a key immunological mechanism contributing to insulin resistance (IR), pancreatic β-cell damage, and diabetes progression.
Ruisi Yang, Ruodi Yang, Han Zhang, Yufeng Yang, Yan Shi, Juntong Liu   +5 more
doaj   +1 more source