Results 1 to 10 of about 1,772,071 (229)
Macrophages as tools and targets in cancer therapy
Nature Reviews Drug Discovery, 2022 Tumour-associated macrophages are an essential component of the tumour microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix remodelling, cancer cell proliferation, metastasis and immunosuppression, as well as in ...
Alberto Mantovani +2 more
exaly +2 more sources
Tumor-Associated Macrophages in Tumor Immunity
Frontiers in Immunology, 2020 Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activated ...
Xiaojian Wang, Ting Zhang, Hanno Steen
exaly +2 more sources
Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain [PDF]
Nature Communications, 2020 Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Xiaobing Yu +8 more
semanticscholar +4 more sources
Tumor-Associated Macrophages: Recent Insights and Therapies
Frontiers in Oncology, 2020 Macrophages, which have functions of engulfing and digesting foreign substances, can clear away harmful matter, including cellular debris and tumor cells.
Ziwei Tang, R M Bianchi, Xikun Zhou
exaly +2 more sources
Macrophages as regulators of tumour immunity and immunotherapy
Nature Reviews Immunology, 2019 David G Denardo, Brian Ruffell
exaly +2 more sources
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells
Nature, 2021 Brian D Brown +2 more
exaly +2 more sources
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Nature, 2014 Oscar Colegio, Vikram Jairam, Nika Cyrus
exaly +2 more sources
Resident macrophages and their potential in cardiac tissue engineering [PDF]
, 2021 Many facets of tissue engineered models aim to understand cellular mechanisms to recapitulate in vivo behavior, study and mimic diseases for drug interventions and to provide better understanding towards improving regenerative medicine.
Applications +4 more
core +2 more sources
Macrophages in immunoregulation and therapeutics
Signal Transduction and Targeted Therapy, 2023 Macrophages exist in various tissues, several body cavities, and around mucosal surfaces and are a vital part of the innate immune system for host defense against many pathogens and cancers.
Shanze Chen +7 more
semanticscholar +1 more source
In silico prediction of protein-protein interactions in human macrophages [PDF]
BMC Research Notes, 2001 Protein-protein interaction (PPI) network analyses are highly valuable in deciphering and understanding the intricate organisation of cellular functions.
Oussema Souiai +4 more
semanticscholar +1 more source