Results 21 to 30 of about 1,368,417 (273)
Gut microbiota is a constant source of antigens and stimuli to which the resident immune system has developed tolerance. However, the mechanisms by which mononuclear phagocytes, specifically monocytes/macrophages, cope with these usually pro-inflammatory
Aize Pellon+24 more
doaj +1 more source
Background: Vascular calcification (VC) is a cardiovascular complication associated with a high mortality rate among patients with diseases such as atherosclerosis and chronic kidney disease.
Linda Yaker+14 more
doaj +1 more source
Enhanced susceptibility to bacterial infection in the days following an acute virus infection such as flu is a major clinical problem. Mouse models have provided major advances in understanding viral-bacterial superinfections, yet interactions of the ...
Laurent Boucontet+13 more
doaj +1 more source
We evaluated in vitro anti-obesity and immunostimulatory activity of wood cultivated ginseng. The roots (WCG-R) and stems (WCG-S) of wood cultivated ginseng reduced the lipid accumulation and TG contents in 3T3-L1 cells.
Na Gyeong Geum+10 more
doaj +1 more source
Tumor-Associated Macrophages in Tumor Immunity
Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activated ...
Yueyun Pan+3 more
semanticscholar +1 more source
Sageretia thea fruits (STF) are known to have a higher content of functional ingredients and nutrients than blueberries, but studies related to its pharmacological activity are insufficient.
Hyun Ji Eo+2 more
doaj +1 more source
The elegance of a macrophage [PDF]
In the latest issue of Nature Immunology, Piccolo et al.1 elegantly explored the effect of coexisting interferon-γ (IFN-γ) and interleukin 4 (IL-4) antagonistic signals on macrophage transcriptional and epigenetic profiles and, interestingly, identified a plastic cross-talk as opposed to mutually exclusive programs between M1 and M2 polarized ...
M. De Santis, M. Locati, C. Selmi
openaire +2 more sources
The alveolar macrophage. [PDF]
The pulmonary macrophagic system is critical to the defense of the lung, keeping the alveoli clean and sterile and responding on demand with an adaptive outpouring of new cells into the air sacs. Under basal conditions alveolar macrophages, in common with other mononuclear phagocytes, are derived from the bone marrow.
openaire +5 more sources
Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate immune response.
Christelle Langevin+9 more
doaj +1 more source
Alphaviruses, such as chikungunya virus (CHIKV) and Sindbis virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients.
Gabriella Passoni+12 more
doaj +1 more source