Results 21 to 30 of about 1,818,468 (377)
The complex TIE between macrophages and angiogenesis [PDF]
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M.+81 more
core +2 more sources
Adult skeletal muscle is capable of active and efficient differentiation in the event of injury in both physiological and pathological conditions, such as in Duchenne muscular dystrophy (DMD).
Valerio Laghi+3 more
doaj +1 more source
Segmentation based tracking of cells in 2D+time microscopy images of macrophages [PDF]
The automated segmentation and tracking of macrophages during their migration are challenging tasks due to their dynamically changing shapes and motions. This paper proposes a new algorithm to achieve automatic cell tracking in time-lapse microscopy macrophage data.
arxiv +1 more source
Age-related changes to macrophages are detrimental to fracture healing in mice. [PDF]
The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age ...
Brazina, Sloane+8 more
core +2 more sources
PTEN inhibits AMPK to control collective migration
Pten is a tumour suppressor gene that is associated with highly invasive cancers such as glioblastoma. Here the authors show that PTEN loss results in increased migratory behaviour, which can be countered by targeting AMPK activity.
Florent Peglion+9 more
doaj +1 more source
Enhanced susceptibility to bacterial infection in the days following an acute virus infection such as flu is a major clinical problem. Mouse models have provided major advances in understanding viral-bacterial superinfections, yet interactions of the ...
Laurent Boucontet+13 more
doaj +1 more source
M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes. [PDF]
Acute injury in the setting of liver fibrosis is an interesting and still unsettled issue. Most recently, several prominent studies have indicated the favourable effects of liver fibrosis against acute insults.
Bai, Li+13 more
core +2 more sources
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Primitive Origins for Microglia Microglia are the resident macrophages of the central nervous system and are associated with neurodegeneration and brain inflammatory diseases.
F. Ginhoux+12 more
semanticscholar +1 more source
Macrophages promote the progression of premalignant mammary lesions to invasive cancer. [PDF]
Breast cancer initiation, progression and metastasis rely on a complex interplay between tumor cells and their surrounding microenvironment. Infiltrating immune cells, including macrophages, promote mammary tumor progression and metastasis; however, less
Anderson+49 more
core +1 more source
Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate immune response.
Christelle Langevin+9 more
doaj +1 more source