Results 21 to 30 of about 1,368,417 (273)

The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes

open access: yesGut Microbes, 2021
Gut microbiota is a constant source of antigens and stimuli to which the resident immune system has developed tolerance. However, the mechanisms by which mononuclear phagocytes, specifically monocytes/macrophages, cope with these usually pro-inflammatory
Aize Pellon   +24 more
doaj   +1 more source

Extracellular Vesicles From LPS-Treated Macrophages Aggravate Smooth Muscle Cell Calcification by Propagating Inflammation and Oxidative Stress

open access: yesFrontiers in Cell and Developmental Biology, 2022
Background: Vascular calcification (VC) is a cardiovascular complication associated with a high mortality rate among patients with diseases such as atherosclerosis and chronic kidney disease.
Linda Yaker   +14 more
doaj   +1 more source

A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death

open access: yesFrontiers in Immunology, 2018
Enhanced susceptibility to bacterial infection in the days following an acute virus infection such as flu is a major clinical problem. Mouse models have provided major advances in understanding viral-bacterial superinfections, yet interactions of the ...
Laurent Boucontet   +13 more
doaj   +1 more source

Wood cultivated ginseng exerts immunostimulatory activity in mouse macrophages, RAW264.7 cells and anti-obesity activity in mouse adipocytes, 3T3-l1 cells

open access: yesFood and Agricultural Immunology, 2021
We evaluated in vitro anti-obesity and immunostimulatory activity of wood cultivated ginseng. The roots (WCG-R) and stems (WCG-S) of wood cultivated ginseng reduced the lipid accumulation and TG contents in 3T3-L1 cells.
Na Gyeong Geum   +10 more
doaj   +1 more source

Tumor-Associated Macrophages in Tumor Immunity

open access: yesFrontiers in Immunology, 2020
Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activated ...
Yueyun Pan   +3 more
semanticscholar   +1 more source

In vitro macrophage activation by Sageretia thea fruits through TLR2/TLR4-dependent activation of MAPK, NF-κB and PI3K/AKT signalling in RAW264.7 cells

open access: yesFood and Agricultural Immunology, 2021
Sageretia thea fruits (STF) are known to have a higher content of functional ingredients and nutrients than blueberries, but studies related to its pharmacological activity are insufficient.
Hyun Ji Eo   +2 more
doaj   +1 more source

The elegance of a macrophage [PDF]

open access: yesCellular & Molecular Immunology, 2017
In the latest issue of Nature Immunology, Piccolo et al.1 elegantly explored the effect of coexisting interferon-γ (IFN-γ) and interleukin 4 (IL-4) antagonistic signals on macrophage transcriptional and epigenetic profiles and, interestingly, identified a plastic cross-talk as opposed to mutually exclusive programs between M1 and M2 polarized ...
M. De Santis, M. Locati, C. Selmi
openaire   +2 more sources

The alveolar macrophage. [PDF]

open access: yesEnvironmental Health Perspectives, 1971
The pulmonary macrophagic system is critical to the defense of the lung, keeping the alveoli clean and sterile and responding on demand with an adaptive outpouring of new cells into the air sacs. Under basal conditions alveolar macrophages, in common with other mononuclear phagocytes, are derived from the bone marrow.
openaire   +5 more sources

FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection

open access: yesFrontiers in Immunology, 2017
Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate immune response.
Christelle Langevin   +9 more
doaj   +1 more source

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes

open access: yesDisease Models & Mechanisms, 2017
Alphaviruses, such as chikungunya virus (CHIKV) and Sindbis virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients.
Gabriella Passoni   +12 more
doaj   +1 more source

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