Results 41 to 50 of about 1,368,417 (273)
Nature Reviews Immunology, 2016 Macrophages expressing PPARγ support skeletal muscle regeneration by inducing secretion of the myoblast growth factor GDF3.
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HDL and plaque regression in a multiphase model of early atherosclerosis [PDF]
, 2023 Atherosclerotic plaques are accumulations of cholesterol-engorged macrophages in the artery wall. Plaque growth is initiated and sustained by the deposition of low density lipoproteins (LDL) in the artery wall. High density lipoproteins (HDL) counterbalance the effects of LDL by accepting cholesterol from macrophages and removing it from the plaque. In
arxiv +1 more source
Interaction between macrophages and ferroptosis
Cell Death and Disease, 2022 Ferroptosis, a newly discovered iron-dependent cell death pathway, is characterized by lipid peroxidation and GSH depletion mediated by iron metabolism and is morphologically, biologically and genetically different from other programmed cell deaths ...
Yan Yang +5 more
semanticscholar +1 more source
Frontiers in Immunology, 2019 Currently, inflammatory bowel disease (IBD) is a serious public health problem on the rise worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal inflammation triggered by food intake.
Maximo Coronado +5 more
doaj +1 more source
A Lipid-Structured Model of Atherosclerotic Plaque Macrophages with Lipid-Dependent Kinetics [PDF]
arXiv, 2022 Atherosclerotic plaques are fatty growths in artery walls that cause heart attacks and strokes. Plaque formation is orchestrated by macrophages that are recruited to the artery wall to consume and remove blood-derived lipids, such as low-density lipoprotein (LDL).
arxiv
The pulmonary macrophage. [PDF]
Environmental Health Perspectives, 1976 An overview of the pulmonary macrophage is provided, with particular emphasis on the origin of this cell and the adaptive mechanisms whereby the macrophagic system is able to respond to increased inhalant loads of organic and inorganic pollutants. Evidence is presented which favors an hematopoietic origin for the alveolar macrophage with a monocytic ...
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Macrophages in Lung Injury, Repair, and Fibrosis
Cells, 2021 Fibrosis progression in the lung commonly results in impaired functional gas exchange, respiratory failure, or even death. In addition to the aberrant activation and differentiation of lung fibroblasts, persistent alveolar injury and incomplete repair ...
Peiyong Cheng +2 more
semanticscholar +1 more source
Macrophages: The Good, the Bad, and the Gluttony
Frontiers in Immunology, 2021 Macrophages are dynamic cells that play critical roles in the induction and resolution of sterile inflammation. In this review, we will compile and interpret recent findings on the plasticity of macrophages and how these cells contribute to the ...
E. Ross, A. Devitt, Jill R. Johnson
semanticscholar +1 more source
Frontiers in Immunology, 2021 Inflammation is a fundamental physiological response orchestrated by innate immune cells to restore tissue homeostasis. Specialized pro-resolving mediators (SPMs) are involved in active resolution of inflammation but when inflammation is incomplete ...
Margot Lavy +4 more
doaj +1 more source
PD-1 expression by tumor-associated macrophages inhibits phagocytosis and tumor immunity
Nature, 2017 Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor that is upregulated on activated T cells for the induction of immune tolerance.
S. Gordon +12 more
semanticscholar +1 more source