Results 41 to 50 of about 1,818,468 (377)
Frontiers in Immunology, 2020 Dendritic cells (DCs) are central in regulating immune responses of kidney ischemia-reperfusion injury (IRI), and strategies to alter DC function may provide new therapeutic opportunities.
Thomas V. Rousselle +10 more
doaj +1 more source
The in silico macrophage: toward a better understanding of inflammatory disease [PDF]
Genome Medicine 2011, 3:4 (22 January 2011), 2011 Macrophages function as sentinel, cell-regulatory hubs capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state. Highly complex and varied gene expression programs within the macrophage enable such functional diversity.
arxiv +1 more source
Frontiers in Immunology, 2019 Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis is established. Others are derived from blood monocytes.
M. Orecchioni +3 more
semanticscholar +1 more source
PCSK9 induces a pro-inflammatory response in macrophages [PDF]
, 2018 Intraplaque release of inflammatory cytokines from macrophages is implicated in atherogenesis by inducing the proliferation and migration of media smooth muscle cells (SMCs). PCSK9 is present and released by SMCs within the atherosclerotic plaque but its
Adorni, Maria Pia +12 more
core +3 more sources
A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages [PDF]
arXiv, 2022 Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction between monocyte-derived macrophages and extracellular lipid. Although concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles in the blood
arxiv
HDL and plaque regression in a multiphase model of early atherosclerosis [PDF]
, 2023 Atherosclerotic plaques are accumulations of cholesterol-engorged macrophages in the artery wall. Plaque growth is initiated and sustained by the deposition of low density lipoproteins (LDL) in the artery wall. High density lipoproteins (HDL) counterbalance the effects of LDL by accepting cholesterol from macrophages and removing it from the plaque. In
arxiv +1 more source
Alveolar macrophages and the diagnosis of drowning [PDF]
, 1993 In the present study, we examined the number of alveolar macrophages in lung tissue from 17 cases of fresh water drowning, 22 cases of acute death and 6 cases of lung emphysema.
A. Nerlich +12 more
core +1 more source
Frontiers in Immunology, 2019 Currently, inflammatory bowel disease (IBD) is a serious public health problem on the rise worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal inflammation triggered by food intake.
Maximo Coronado +5 more
doaj +1 more source
Frontiers in Physiology, 2020 An early event in atherogenesis is the recruitment and infiltration of circulating monocytes and macrophage activation in the subendothelial space.
Thiago Rentz +6 more
doaj +1 more source
Macrophages and Metabolic Reprograming in the Tumor Microenvironment
Frontiers in Oncology, 2022 Due to the emergence of traditional drug resistance in tumor treatment, the anti-cancer therapies are facing multiple challenges. Immunotherapy, as a new and universal treatment, has been gradually concerned.
Jin Liu +15 more
doaj +1 more source