Results 51 to 60 of about 2,020,072 (390)
Frontiers in Immunology, 2019 Currently, inflammatory bowel disease (IBD) is a serious public health problem on the rise worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal inflammation triggered by food intake.
Maximo Coronado +5 more
doaj +1 more source
Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages [PDF]
, 2018 Background: As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophages tightly control the angiogenic
Blandino, Giovanni +14 more
core +3 more sources
The pulmonary macrophage. [PDF]
Environmental Health Perspectives, 1976 An overview of the pulmonary macrophage is provided, with particular emphasis on the origin of this cell and the adaptive mechanisms whereby the macrophagic system is able to respond to increased inhalant loads of organic and inorganic pollutants. Evidence is presented which favors an hematopoietic origin for the alveolar macrophage with a monocytic ...
openaire +2 more sources
Targeting macrophages in cancer immunotherapy
Signal Transduction and Targeted Therapy, 2021 Immunotherapy is regarded as the most promising treatment for cancers. Various cancer immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies, immune checkpoint inhibitors, and small-molecule inhibitors, have achieved ...
Z. Duan, Yunping Luo
semanticscholar +1 more source
Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]
, 2012 Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Weidenbusch, Marc, Anders, Hans-Joachim
core +1 more source
New insights into M1/M2 macrophages: key modulators in cancer progression
Cancer Cell International, 2021 Infiltration of macrophages in and around tumor nest represents one of the most crucial hallmarks during tumor progression. The mutual interactions with tumor cells and stromal microenvironment contribute to phenotypically polarization of tumor ...
Jiuyang Liu +3 more
semanticscholar +1 more source
Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. [PDF]
, 2019 Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic drainage and/or bloodstream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood.
Ferreira, Fernando +14 more
core +2 more sources
Frontiers in Immunology, 2019 Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis is established. Others are derived from blood monocytes.
Marco Orecchioni +3 more
semanticscholar +1 more source
Macrophages in Lung Injury, Repair, and Fibrosis
Cells, 2021 Fibrosis progression in the lung commonly results in impaired functional gas exchange, respiratory failure, or even death. In addition to the aberrant activation and differentiation of lung fibroblasts, persistent alveolar injury and incomplete repair ...
Peiyong Cheng +2 more
semanticscholar +1 more source
Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]
, 2010 Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M. +8 more
core +1 more source