Results 51 to 60 of about 1,971,731 (404)

Calcium phosphate: a substitute for aluminum adjuvants?

Expert Review of Vaccines, 2017
Introduction: Calcium phosphate was used as an adjuvant in France in diphtheria, tetanus, pertussis and poliomyelitis vaccines. It was later completely substituted by alum salts in the late 80’s, but it still remains as an approved adjuvant for the World
Jean-Daniel Masson, Michel Thibaudon, Laurent Bélec, Guillemette Crépeaux   +3 more
doaj   +1 more source

Nrf2 Promotes Inflammation in Early Myocardial Ischemia-Reperfusion via Recruitment and Activation of Macrophages

Frontiers in Immunology, 2021
Cardiomyocyte apoptosis in response to inflammation is a primary cause of myocardial ischemia-reperfusion injury (IRI). Nuclear factor erythroid 2 like 2 (Nrf2) reportedly plays an important role in myocardial IRI, but the underlying mechanism remains ...
Haijian Zhang, Haijian Zhang, Yifei Liu, Xiaoqing Cao, Wenmiao Wang, Xiaohong Cui, Xuechao Yang, Yan Wang, Jiahai Shi, Jiahai Shi   +9 more
doaj   +1 more source

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner [PDF]

Open Biology, 2021
Nucleic acid sensing through pattern recognition receptors is critical for immune recognition of microbial infections. Microbial DNA is frequently methylated at the N6 position of adenines (m6A), a modification ...
Melania Balzarolo, Sander Engels, Anja J. de Jong, Katka Franke, Timo K. van den Berg, Muhammet F. Gulen, Andrea Ablasser, Edith M. Janssen, Bas van Steensel, Monika C. Wolkers   +9 more
doaj   +1 more source

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Journal of Clinical Investigation, 1998
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue remodeling, regulation of the immune response, or resolution of inflammation.
V. Fadok, D. Bratton, A. Konowal, Peter W. Freed, J. Westcott, P. Henson   +5 more
semanticscholar   +1 more source

New insights into M1/M2 macrophages: key modulators in cancer progression

Cancer Cell International, 2021
Infiltration of macrophages in and around tumor nest represents one of the most crucial hallmarks during tumor progression. The mutual interactions with tumor cells and stromal microenvironment contribute to phenotypically polarization of tumor ...
Jiuyang Liu, Xia-fei Geng, J. Hou, Gaosong Wu   +3 more
semanticscholar   +1 more source

Alveolar macrophages and the diagnosis of drowning [PDF]

, 1993
In the present study, we examined the number of alveolar macrophages in lung tissue from 17 cases of fresh water drowning, 22 cases of acute death and 6 cases of lung emphysema.
A. Nerlich, Brinkmann, Brinkmann, Cordell, Janssen, Mueller, P. Betz, Püschel, R. Penning, Reh, Reh, Timperman, W. Eisenmenger   +12 more
core   +1 more source

Kadsura japonica fruits exert immunostimulatory and anti-obesity activity in RAW264.7 and 3T3-L1 cells

Food and Agricultural Immunology, 2022
Under the COVID-19 pandemic, interest in immune enhancement and anti-obesity is increasing. Thus, in this study, we investigated whether Kadsura japonica fruits (KJF) exhibits immunostimulatory activity and anti-obesity activity.
Na Gyeong Geum, Ho Jun Son, Ju Hyung Yu, Joo Ho Yeo, Min Yeong Choi, Jae Won Lee, Jueng Kyu Baek, Hyun Ji Eo, Gwang Hun Park, Jin Boo Jeong   +9 more
doaj   +1 more source

Culture System for a Closer Biological Contact Between Macrophages and Microparticles

Frontiers in Mechanical Engineering, 2021
To investigate the effects of microparticles on the immune system, a device was designed for an optimal culture environment. Macrophages phagocytose microparticles and produce inflammatory cytokines.
Haruki Miyamoto, Katsunori Higuchi, Yuta Nakashima, Yukio Fujiwara, Yoshihiro Komohara, Yoshitaka Nakanishi   +5 more
doaj   +1 more source

Macrophages in xenotransplantation [PDF]

Korean Journal of Transplantation, 2019
Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed the involvement of macrophages in xenograft and allograft rejections.
openaire   +4 more sources

Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts. [PDF]

, 2012
The inhibition of death-receptor apoptosis is a conserved viral function. The murine cytomegalovirus (MCMV) gene M36 is a sequence and functional homologue of the human cytomegalovirus gene UL36, and it encodes an inhibitor of apoptosis that binds to ...
A Orvedahl, A Schaap-Nutt, A Skaletskaya, AL McCormick, C Mack, C Menard, Carlos A. Guzmán, CE Patterson, D Arnoult, D Lembo, HG Burgert, I Jurak, J Bertin, JL Davignon, JW Upton, L Cicin-Sain, L Cicin-Sain, Linda Ebermann, LK Hanson, Luka Čičin-Šain, M Chaumorcel, M Reboredo, Michele Barry, MJ Reddehase, ML Nguyen, N van Rooijen, N van Rooijen, N van Rooijen, Nico van Rooijen, P Lucin, PM Fliss, Rosaely Casalegno-Garduño, S Hamano, Ulrich Koszinowski, VS Goldmacher, W Brune, W Brune, WJ Kaiser, Zsolt Ruzsics   +38 more
core   +6 more sources