Results 91 to 100 of about 990 (199)

Controversial issues in the management of hyperprolactinemia and prolactinomas – An overview by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism

open access: yesArchives of Endocrinology and Metabolism
Prolactinomas are the most common pituitary adenomas (approximately 40% of cases), and they represent an important cause of hypogonadism and infertility in both sexes.
Lucio Vilar   +24 more
doaj   +1 more source

Macroprolactin - rational use of screening test in diagnostic of hyperprolactinaemia [PDF]

open access: yes, 2018
Određivanje koncentracije prolaktina u serumu ima najveći klinički značaj u diferencijalnoj dijagnostici hiperprolaktinemije. Budući da je fiziologija djelovanja i regulacije lučenja prolaktina u krvi vrlo složena, postoje različiti čimbenici koji utječu
Šostarić, Milica
core  

Assessment of macroprolactinemia by polyethylene glycol precipitation method

open access: yes, 2014
BackgroundMacroprolactin is a molecule that results from association between monomeric prolactin (PRL) and immunoglobulin G (IgG). It has longer half-life and is considered biologically inactive, although it retains immunoreactivity, being detected in ...
Pacheco, Ana   +4 more
core   +1 more source

Postmenopausal Hook Effect

open access: yesEndocrinology Research and Practice, 2018
Introduction: Prolactinoma is the most common functional pituitary adenoma. The degree of serum prolactin (PRL) is correlated with the size of adenoma and the PRL level is usually >250 ng/dL in macroprolactinomas.
Rumeysa Çolak   +6 more
doaj   +1 more source

Should macroprolactin be measured in all hyperprolactinaemic sera? [PDF]

open access: yesClinical Endocrinology, 2009
SummaryMacroprolactin is a nonbioactive prolactin isoform usually composed of a monomer of prolactin and a IgG molecule which has a prolonged clearance rate similar to that of the immunoglobulins. Macroprolactinaemia, hyperprolactinaemia entirely accounted for by the presence of macroprolactin, is estimated to account for approximately 10% of all ...
openaire   +2 more sources

Patients with macroprolactinaemia : clinical and radiological features

open access: yes, 2007
Background: Macroprolactinaemia may represent a relevant cause of misdiagnosis, unnecessary investigation and inappropriate treatment. The aim of this study was to investigate the clinical and neuroradiological characteristics of patients with and ...
A. Spada   +6 more
core   +1 more source

Macroprolactinemia and Empty Sella Syndrome

open access: yesThe Pan African Medical Journal, 2017
Macroprolactinemia is a polymeric form of prolactin-release, causing mildly symptomatic clinical pictures. The former can be isolated or associated with other causes of hyperprolactinemia. The association with an empty sella syndrome is rare. We report a
Ach Taieb   +5 more
doaj   +1 more source

The lmportance of Macroprolactin in the Differential Diagnosis of Hyperprolactinemia

open access: yes, 2020
The aim of this study: To evaluate the significance of macroprolactin for differential diagnosis of hyperprolactinemia. Objectives of work: 1. To estimate the frequency of macroprolactinaemia in patients with hyperprolactinemia. 2.
Jašmontaitė, Vaida
core  

Prolactin and Macroprolactin in Systemic Lupus Erythematosus (SLE) [PDF]

open access: yes, 2005
Existem fortes evidências sobre a influência dos hormônios sexuais na imunidade e na apresentação de doenças auto-imunes, entre elas o lúpus eritematoso sistêmico (LES).
Tiskievicz, Fabiane   +3 more
core  

Detection of molecular variants of prolactin in human serum, evaluation of a method based on ultrafiltration

open access: yes, 2007
BackgroundIn human blood, there are several molecular variants of prolactin with different biological effects. There is a need for new methods to detect and quantify these variants in order to fully understand the pathophysiological role of prolactin ...
Arvidsson, Britt-Marie,   +4 more
core   +1 more source

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