Macroprolactinemia in childhood and adolescence: a cause of hyperprolactinemia [PDF]
The Turkish Journal of Pediatrics, 2006 Human prolactin consists of multiple forms of different sizes including three major prolactin (PRL) species, termed as little, big, and big-big PRL.
Filiz Tütüncüler +3 more
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The Correlation Between DRD2 and COMT Gene Polymorphisms, HPT and HPG Axes Functions, and Antipsychotic Drug-Induced Hyperprolactinemia and Macroprolactinemia [PDF]
Neuropsychiatric Disease and TreatmentZhenhua Wang,1 Jing Li,2 Haizhi Chen,1 Haiying Jin,1 Shiliang Wang,1 Xuqiang Hu1 1Department of Psychiatry, Huzhou Third Municipal Hospital, the Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, People’s Republic of China; 2Center for Disease ...
Wang Z +5 more
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Macroprolactinemia in patients with hyperprolactinemia: an experience from a single tertiary center [PDF]
The Pan African Medical Journal, 2020 Macroprolactinemia frequently causes misdiagnosis, unnecessary investigation and inappropriate treatment in hyperprolactinemic patients. Aim of this study is to investigate the prevalence and clinical characteristics of Thai patients with ...
Phronpan Chutpiboonwat +5 more
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Establishment of reference intervals of monomeric prolactin to identify macroprolactinemia in Chinese patients with increased total prolactin [PDF]
BMC Endocrine Disorders, 2021 Background Macroprolactin is responsible for pseudohyperprolactinemia and is a common pitfall of the prolactin immunoassay. We aimed to determine the frequency of macroprolactinemia in Chinese hyperprolactinemic patients using monomeric prolactin ...
Yao Hu +8 more
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The Effect of Metformin on Pituitary Function in Postmenopausal Women with Subclinical Hypothyroidism and Macroprolactinemia: A Single-Center Prospective Case–Control Study [PDF]
PharmaceuticalsBackground/Objectives: Metformin inhibits secretory function of overactive thyrotrophs, gonadotrophs, and lactotrophs. The clinical significance of an excess of high-molecular-weight prolactin (macroprolactinemia) remains unclear.
Robert Krysiak +3 more
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Usefulness of prolactin levels in predicting the etiology of hyperprolactinemia in a cohort of 770 patients [PDF]
Archives of Endocrinology and MetabolismObjective Determining the etiology of hyperprolactinemia is fundamental for selecting the most appropriate treatment strategy. The aim of this study was to evaluate the usefulness and accuracy of prolactin levels in predicting the etiology of ...
Lucio Vilar +18 more
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Macroprolactinemia: a mini-review and update on clinical practice [PDF]
F&S Reports, 2023 Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine Koniares, M.D. +4 more
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Laboratory and clinical significance of macroprolactinemia in women with hyperprolactinemia
Taiwanese Journal of Obstetrics & Gynecology, 2017 The role of macroprolactinemia in women with hyperprolactinemia is currently controversial and can lead to clinical dilemmas, depending upon the origin of macroprolactin, the presence of hyperprolactinemic symptoms and monomeric prolactin (PRL) levels ...
Miro Kasum +5 more
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Serum prolactin revisited:parametric reference intervals and cross platform evaluation of polyethylene glycol precipitation-based methods for discrimination between hyperprolactinemia and macroprolactinemia [PDF]
, 2017 Background:Hyperprolactinemia diagnosis and treatment is often compromised by the presence of biologically inactive and clinically irrelevant higher-molecular-weight complexes of prolactin, macroprolactin.
Overgaard, Martin +1 more
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Position statement on macroprolactinemia from the Department of Neuroendocrinology of the Brazilian Society of Endocrinology and Metabolism (SBEM) and the Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) [PDF]
Archives of Endocrinology and MetabolismMeasurement of serum prolactin levels is a common practice in clinical settings, particularly among women of reproductive age. In cases of hyperprolactinemia, identifying macroprolactinemia can help prevent unnecessary investigation and inappropriate ...
Andrea Glezer +10 more
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