Results 1 to 10 of about 433 (148)
Establishment of reference intervals of monomeric prolactin to identify macroprolactinemia in Chinese patients with increased total prolactin [PDF]
Background Macroprolactin is responsible for pseudohyperprolactinemia and is a common pitfall of the prolactin immunoassay. We aimed to determine the frequency of macroprolactinemia in Chinese hyperprolactinemic patients using monomeric prolactin ...
Yao Hu+8 more
doaj +4 more sources
Prevalence of Macroprolactinemia in People Detected to Have Hyperprolactinemia. [PDF]
AbstractBackground Macroprolactinemia is an analytic laboma encountered as a part of prolactin assay. No data are available on the burden of macroprolactinemia in Indians. This study aimed to determine the prevalence and predictors of macroprolactinemia among people with hyperprolactinemia.Methods Consecutive patients detected to have serum prolactin ...
Sharma LK+5 more
europepmc +5 more sources
Macroprolactinemia: a mini-review and update on clinical practice [PDF]
Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine Koniares, M.D.+4 more
doaj +4 more sources
Laboratory and clinical significance of macroprolactinemia in women with hyperprolactinemia
The role of macroprolactinemia in women with hyperprolactinemia is currently controversial and can lead to clinical dilemmas, depending upon the origin of macroprolactin, the presence of hyperprolactinemic symptoms and monomeric prolactin (PRL) levels ...
Miro Kasum+5 more
doaj +5 more sources
Macroprolactinemia in childhood and adolescence: a cause of hyperprolactinemia
Human prolactin consists of multiple forms of different sizes including three major prolactin (PRL) species, termed as little, big, and big-big PRL.
Filiz Tütüncüler+3 more
doaj +5 more sources
Macroprolactinemia and Empty Sella Syndrome [PDF]
Macroprolactinemia is a polymeric form of prolactin-release, causing mildly symptomatic clinical pictures. The former can be isolated or associated with other causes of hyperprolactinemia. The association with an empty sella syndrome is rare. We report a
Ach Taieb+5 more
doaj +4 more sources
Macroprolactinemia: a New Cause of Hyperprolactinemia
Hyperprolactinemia is not only seen in pregnancy but also in several pathological conditions such as prolactin (PRL) secreting pituitary adenoma (prolactinoma), intracranial tumors compressing the pituitary stalk or hypothalamus, and PRL stimulative ...
Naoki Hattori
doaj +6 more sources
Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia
Macroprolactinemia is often a cause of misdiagnosis, unnecessary expensive investigation, and unsuitable treatment. The aim of the present study was to investigate the clinical findings and the concentrations of macroprolactin in patients with ...
Murat Can+4 more
doaj +6 more sources
A dosagem de prolactina é teste de rotina em numerosas condições da prática clínica, e o encontro de hiperprolactinemia pode desencadear outros protocolos diagnósticos mais complexos e custosos. A prolactina é um hormônio bastante heterogêneo e, do ponto de vista de peso molecular, existem três formas principais em circulação: monômero de 23kDa, dímero
José Gilberto H. Vieira
openalex +6 more sources
Macroprolactinemia Revisited: A Study on 106 Patients [PDF]
The predominance of high molecular weight PRL, or macroprolactinemia, has long been known in hyperprolactinemic patients with maintained fertility. Among 1,106 consecutive patients investigated for hyperprolactinemia in our center over a 10-yr period, serum PRL chromatography was performed in 368 cases because of discordant clinical, biological, or ...
S. Vallette-Kasic
+6 more sources