Macroprolactinemia in childhood and adolescence: a cause of hyperprolactinemia [PDF]
The Turkish Journal of Pediatrics, 2006 Human prolactin consists of multiple forms of different sizes including three major prolactin (PRL) species, termed as little, big, and big-big PRL.
Filiz Tütüncüler +3 more
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Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia [PDF]
Kaohsiung Journal of Medical Sciences, 2011 Macroprolactinemia is often a cause of misdiagnosis, unnecessary expensive investigation, and unsuitable treatment. The aim of the present study was to investigate the clinical findings and the concentrations of macroprolactin in patients with ...
Murat Can +4 more
doaj +7 more sources
The Correlation Between DRD2 and COMT Gene Polymorphisms, HPT and HPG Axes Functions, and Antipsychotic Drug-Induced Hyperprolactinemia and Macroprolactinemia [PDF]
Neuropsychiatric Disease and TreatmentZhenhua Wang,1 Jing Li,2 Haizhi Chen,1 Haiying Jin,1 Shiliang Wang,1 Xuqiang Hu1 1Department of Psychiatry, Huzhou Third Municipal Hospital, the Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, People’s Republic of China; 2Center for Disease ...
Wang Z +5 more
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Establishment of reference intervals of monomeric prolactin to identify macroprolactinemia in Chinese patients with increased total prolactin [PDF]
BMC Endocrine Disorders, 2021 Background Macroprolactin is responsible for pseudohyperprolactinemia and is a common pitfall of the prolactin immunoassay. We aimed to determine the frequency of macroprolactinemia in Chinese hyperprolactinemic patients using monomeric prolactin ...
Yao Hu +8 more
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Macroprolactinemia in patients with hyperprolactinemia: an experience from a single tertiary center [PDF]
The Pan African Medical Journal, 2020 Macroprolactinemia frequently causes misdiagnosis, unnecessary investigation and inappropriate treatment in hyperprolactinemic patients. Aim of this study is to investigate the prevalence and clinical characteristics of Thai patients with ...
Phronpan Chutpiboonwat +5 more
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The Effect of Metformin on Pituitary Function in Postmenopausal Women with Subclinical Hypothyroidism and Macroprolactinemia: A Single-Center Prospective Case–Control Study [PDF]
PharmaceuticalsBackground/Objectives: Metformin inhibits secretory function of overactive thyrotrophs, gonadotrophs, and lactotrophs. The clinical significance of an excess of high-molecular-weight prolactin (macroprolactinemia) remains unclear.
Robert Krysiak +3 more
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Macroprolactinemia: a mini-review and update on clinical practice [PDF]
F&S Reports, 2023 Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine Koniares, M.D. +4 more
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Laboratory and clinical significance of macroprolactinemia in women with hyperprolactinemia
Taiwanese Journal of Obstetrics & Gynecology, 2017 The role of macroprolactinemia in women with hyperprolactinemia is currently controversial and can lead to clinical dilemmas, depending upon the origin of macroprolactin, the presence of hyperprolactinemic symptoms and monomeric prolactin (PRL) levels ...
Miro Kasum +5 more
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Usefulness of prolactin levels in predicting the etiology of hyperprolactinemia in a cohort of 770 patients [PDF]
Archives of Endocrinology and MetabolismObjective Determining the etiology of hyperprolactinemia is fundamental for selecting the most appropriate treatment strategy. The aim of this study was to evaluate the usefulness and accuracy of prolactin levels in predicting the etiology of ...
Lucio Vilar +18 more
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Antipsychotics-induced hyperprolactinemia and screening for macroprolactin. [PDF]
Biochem Med (Zagreb), 2021 Introduction: High prolactin (PRL) concentrations are found in laboratory test results of patients on majority of antipsychotic drugs. Prevalence rates and degrees of severity of hyperprolactinemia (HPRL) based on PRL concentration may depend on the ...
Ruljancic N +7 more
europepmc +3 more sources