Results 11 to 20 of about 433 (148)
Macroprolactinemia: Diagnostic, Clinical, and Pathogenic Significance [PDF]
Clinical and Developmental Immunology, 2012 Macroprolactinemia is characterized by a large molecular mass of PRL (macroprolactin) as the main molecular form of PRL in sera, the frequent elevation of serum PRL (hyperprolactinemia), and the lack of symptoms.
Akira Shimatsu, Naoki Hattori
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Macroprolactinemia in a Patient with Invasive Macroprolactinoma: A Case Report and Minireview [PDF]
Case Reports in Endocrinology, 2013 Background. Macroprolactin, the high-molecular prolactin isoform, is considered to be an inactive in vivo product with extrapituitary origin. Patients with macroprolactinemia are usually asymptomatic, with negative pituitary imaging. Based on these data,
Atanaska Elenkova +5 more
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Macroprolactinemia in patients with hyperprolactinemia: an experience from a single tertiary center [PDF]
The Pan African Medical Journal, 2020 Macroprolactinemia frequently causes misdiagnosis, unnecessary investigation and inappropriate treatment in hyperprolactinemic patients. Aim of this study is to investigate the prevalence and clinical characteristics of Thai patients with ...
Phronpan Chutpiboonwat +5 more
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Importance of macroprolactinemia in hyperprolactinemia [PDF]
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2014 Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G. The term 'macroprolactinemia' is used when the concentration of macroprolactin exceeds 60% of the total serum prolactin concentration determined by polyethylene glycol precipitation.
Miro Kasum +6 more
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Persistent idiopathic prolactin elevation merits macroprolactin estimation: A case report and review of literature [PDF]
Journal of Human Reproductive Sciences, 2021 The prevalence of hyperprolactinemia ranges from about 0.4% in an unselected adult population to as high as 9%–17% in women with reproductive disorders. It may cause infertility in about 11% of the oligospermic males.
Krishnaprabha Gautam +5 more
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International Journal of Endocrinology, 2013 Aim. To determine the frequency of macroprolactinemia, its etiology, and the clinical manifestations in patients with hyperprolactinemia presenting with menstrual irregularities, galactorrhea, and/or infertility who were attended by the gynecology ...
Alfredo Leaños-Miranda +4 more
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Metoclopramide Test in Hyperprolactinemic Women With Polycystic Ovarian Syndrome: Old Wine Into New Bottles? [PDF]
Frontiers in Endocrinology, 2022 IntroductionPolycystic ovarian syndrome (PCOS) is the most frequent etiology of anovulation, hyperandrogenism and infertility in women. Its pathophysiology remains poorly elucidated.
Claire Rodier +11 more
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Case Reports in Endocrinology, 2016 Background. Macroprolactinemia is defined as predominance of high molecular weight prolactin forms in the circulation. Although macroprolactin is considered as a biologically inactive molecule, some authorities suggest treatment in symptomatic cases ...
Fatma Dilek Dellal +5 more
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Macroprolactinemia in a young man and review of the literature [PDF]
HORMONES, 2003 A 21-year old man, complaining of headaches and fatigue, with a negative past medical history and a normal clinical examination, underwent a hormonal investigation which revealed hyper-prolactinemia and intact pituitary-gonadal axis. Drug-induced hyperprolactinemia was excluded. Pituitary magnetic resonance imaging indicated a microadenoma in the right
Evangeline Vassilatou +3 more
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The Clinical Characteristics of Macroprolactinemia [PDF]
Journal of Korean Society of Endocrinology, 2005 Background: Prolactin has been identified by gel chromatography to exist is three different forms in human serum; monomeric prolactin (molecular mass 23 kDa), big prolactin (molecular mass 50~60 kDa) and big big prolactin, otherwise known as macroprolactin (molecular mass 150~170 kDa).
Young Ju Choi +8 more
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