Results 11 to 20 of about 802 (183)

Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature [PDF]

Case Reports in Endocrinology, 2016
Background. Macroprolactinemia is defined as predominance of high molecular weight prolactin forms in the circulation. Although macroprolactin is considered as a biologically inactive molecule, some authorities suggest treatment in symptomatic cases ...
Fatma Dilek Dellal, Didem Ozdemir, Cevdet Aydin, Gulfem Kaya, Reyhan Ersoy, Bekir Cakir   +5 more
doaj   +5 more sources

Macroprolactinemia: Diagnostic, Clinical, and Pathogenic Significance [PDF]

Clinical and Developmental Immunology, 2012
Macroprolactinemia is characterized by a large molecular mass of PRL (macroprolactin) as the main molecular form of PRL in sera, the frequent elevation of serum PRL (hyperprolactinemia), and the lack of symptoms.
Akira Shimatsu, Naoki Hattori
doaj   +5 more sources

Macroprolactinemia: a New Cause of Hyperprolactinemia

Journal of Pharmacological Sciences, 2003
Hyperprolactinemia is not only seen in pregnancy but also in several pathological conditions such as prolactin (PRL) secreting pituitary adenoma (prolactinoma), intracranial tumors compressing the pituitary stalk or hypothalamus, and PRL stimulative ...
Naoki Hattori
doaj   +6 more sources

Prevalence of Macroprolactinemia in People Detected to Have Hyperprolactinemia. [PDF]

J Lab Physicians, 2021
AbstractBackground Macroprolactinemia is an analytic laboma encountered as a part of prolactin assay. No data are available on the burden of macroprolactinemia in Indians. This study aimed to determine the prevalence and predictors of macroprolactinemia among people with hyperprolactinemia.Methods Consecutive patients detected to have serum prolactin ...
Sharma LK, Dutta D, Sharma N, Kulshreshtha B, Lal S, Sethi R.   +5 more
europepmc   +5 more sources

Macroprolactinemia in a Patient with Invasive Macroprolactinoma: A Case Report and Minireview [PDF]

Case Reports in Endocrinology, 2013
Background. Macroprolactin, the high-molecular prolactin isoform, is considered to be an inactive in vivo product with extrapituitary origin. Patients with macroprolactinemia are usually asymptomatic, with negative pituitary imaging. Based on these data,
Atanaska Elenkova, Zdravka Abadzhieva, Nikolai Genov, Vladimir Vasilev, Georgi Kirilov, Sabina Zacharieva   +5 more
doaj   +5 more sources

Importance of macroprolactinemia in hyperprolactinemia [PDF]

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2014
Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G. The term 'macroprolactinemia' is used when the concentration of macroprolactin exceeds 60% of the total serum prolactin concentration determined by polyethylene glycol precipitation.
Anderson, Beda-Maluga, Beltran, Bjoro, Bonhoff, Can, D. Pavičić-Baldani, Elenkova, Espinoza, Fahie-Wilson, Fahie-Wilson, Gibney, Glezer, Glezer, Hattori, Hattori, Hattori, Hattori, Hattori, Hattori, Hauache, Isik, J-M. Šarić, J. Blajić, J. Juras, Jackson, Kavanagh, Kavanagh-Wright, Kramer, Leslie, Lewandowski, Lu, M. Kasum, Marrack, McCudden, Olukoga, P. Stanić, Radavelli-Bagatini, S. Orešković, Shimatsu, Suliman, Thirunavakkarasu, Vallette-Kasic, Vilar, Wallace, Whittaker   +45 more
core   +6 more sources

Macroprolactinaemiával társuló hypophysismacroadenoma kezelése quinagoliddal = Macroprolactinemia associated with pituitary macroadenoma: treatment with quinagolide [PDF]

Orvosi Hetilap, 2010
A jelenlegi általános nézet szerint a makroprolaktin biológiailag inaktív molekula, ezért szérumkoncentrációjának növekedése aligha bír patológiai jelentőséggel.
Czirják, Sándor, Kender, Zoltán, Lakatos, Gergely, Rácz, Károly, Szücs, Nikolette   +4 more
core   +6 more sources

Levodopa-refractory hyperprolactinemia and pituitary findings in inherited disorders of biogenic amine metabolism [PDF]

Journal of Inherited Metabolic Disease, Volume 47, Issue 3, Page 431-446, May 2024., 2023
Elevated serum prolactin concentrations occur in inherited disorders of biogenic amine metabolism because dopamine deficiency leads to insufficient inhibition of prolactin secretion.
Porta, F
core   +5 more sources

A case report of multiple endocrine neoplasia type 1 and autoimmune disease: Coincidence or correlation? [PDF]

Medicine (Baltimore), 2021
Rationale:Multiple Endocrine Neoplasia type 1 (MEN1) is a familial syndrome that results from the disruption of a tumor suppressor protein called MENIN.
Chaves C, Nunes da Silva T, Dias Pereira B, Anselmo J, Claro I, Cavaco BM, Saramago A, Leite V.   +7 more
europepmc   +3 more sources

Frequency of Macroprolactinemia in Hyperprolactinemic Women Presenting with Menstrual Irregularities, Galactorrhea, and/or Infertility: Etiology and Clinical Manifestations

International Journal of Endocrinology, 2013
Aim. To determine the frequency of macroprolactinemia, its etiology, and the clinical manifestations in patients with hyperprolactinemia presenting with menstrual irregularities, galactorrhea, and/or infertility who were attended by the gynecology ...
Alfredo Leaños-Miranda, Karla Leticia Ramírez-Valenzuela, Inova Campos-Galicia, Rosario Chang-Verdugo, Lizbeth Zarela Chinolla-Arellano   +4 more
doaj   +2 more sources