Comparison of urinary prolactin and serum/urine prolactin ratio in hyperprolactinemic and macroprolactinemic patients [PDF]
Background Biologically, the monomeric form of prolactin is the most active. In measurement methods, all forms of prolactin are included in the assay; therefore, the presence of macroprolactin, causes a false increase in prolactin and misdiagnosis of ...
Behnam Ein-Mozaffari +8 more
doaj +2 more sources
Macroprolactinemia: a New Cause of Hyperprolactinemia
Hyperprolactinemia is not only seen in pregnancy but also in several pathological conditions such as prolactin (PRL) secreting pituitary adenoma (prolactinoma), intracranial tumors compressing the pituitary stalk or hypothalamus, and PRL stimulative ...
Naoki Hattori
doaj +4 more sources
Objectives: Macroprolactin (macroPRL) excess is an important cause of hyperprolactinemia. Several prolactin assays have high reactivity to macroPRL. However, macroPRL screening is not routinely performed in many labs.
Abdulla Al Nuaimi +4 more
doaj +5 more sources
The importance of routine screening for macroprolactin in symptomatic patients with idiopathic hyperprolactinemia [PDF]
Objective: To evaluate the importance of screening for macroprolactin in symptomatic patients with apparent idiopathic hyperprolactinemia. Methods: During 20 months, the prevalence of macroprolactinemia was evaluated among consecutive symptomatic female
Lucio Vilar +11 more
doaj +3 more sources
Mild hyperprolactinemia in women with polycystic ovary syndrome. Insights from a large cross-sectional study [PDF]
Background: Hyperprolactinemia is an exclusion criterion for polycystic ovary syndrome (PCOS), albeit PCOS itself is argued to induce mild hyperprolactinemia.
Manuel Luque-Ramírez +6 more
doaj +2 more sources
Persistent idiopathic prolactin elevation merits macroprolactin estimation: A case report and review of literature [PDF]
The prevalence of hyperprolactinemia ranges from about 0.4% in an unselected adult population to as high as 9%–17% in women with reproductive disorders. It may cause infertility in about 11% of the oligospermic males.
Krishnaprabha Gautam +5 more
doaj +2 more sources
A macroprolactinemia--da determinação laboratorial ao seu significado clínico.
Since prolactin (PRL) (a hormone produced by the anterior pituitary) was first identificated, the existence of hyperprolactinemic syndrome has been recognized.
Catarina Matos +2 more
doaj +2 more sources
Macroprolactinemia e hiperprolactinemia intermediária: manifestações clínicas e achados radiológicos Macroprolactinemia and intermediate hyperprolactinemia: clinical manifestations and image [PDF]
OBJETIVOS: Caracterizar as pacientes com valores indeterminados de hiperprolactinemia (teste de PEG para identificação de macroprolactinemias com recuperação entre 30 e 65%) (PRLi) ou macroprolactinemia (PRLm), quanto às características clínicas, como ...
Ana Carolina Japur de Sá Rosa-e-Silva +5 more
doaj +3 more sources
A case report of multiple endocrine neoplasia type 1 and autoimmune disease: Coincidence or correlation? [PDF]
Rationale:Multiple Endocrine Neoplasia type 1 (MEN1) is a familial syndrome that results from the disruption of a tumor suppressor protein called MENIN.
Chaves C +7 more
europepmc +3 more sources
Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia
Macroprolactinemia is often a cause of misdiagnosis, unnecessary expensive investigation, and unsuitable treatment. The aim of the present study was to investigate the clinical findings and the concentrations of macroprolactin in patients with ...
Murat Can +4 more
doaj +2 more sources

