Results 1 to 10 of about 120,090 (336)
Real world pharmacovigilance assessment of drug related macular degeneration risks [PDF]
Scientific ReportsMacular degeneration is a leading cause of irreversible vision loss, significantly impacting quality of life. To enhance clinical practice and reduce the risk of drug-related macular degeneration, we analyzed drug-related trends using real-world data ...
Xiaodong Chen +9 more
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Age-related macular degeneration
Clinical Ophthalmology, 2011 Giuseppe Querques¹, Fernando Onofrio Avellis1,2, Lea Querques1,3, Francesco Bandello³, Eric H Souied¹ ¹Service d'Ophtalmologie, Centre Hospitalier Intercommunal Créteil, Université Paris ...
Querques G +4 more
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Sleep, Pain, and Neurodegeneration: A Mendelian Randomization Study
Frontiers in Neurology, 2022 Our aim was to determine whether the genetic liability to sleep and pain-related traits have a causal effect on risk of neurodegeneration in individuals of predominantly European ancestry. We selected five neurodegenerative disorders, namely, age-related
Sandeep Grover +2 more
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On phagocytes and macular degeneration [PDF]
Progress in Retinal and Eye Research, 2017 Age related macular degeneration (AMD) is a complex multifactorial disease caused by the interplay of age and genetic and environmental risk factors. A common feature observed in early and both forms of late AMD is the breakdown of the physiologically immunosuppressive subretinal environment and the protracted accumulation of mononuclear phagocytes (MP)
Xavier Guillonneau +5 more
openaire +8 more sources
Innate immune biology in age-related macular degeneration
Frontiers in Cell and Developmental Biology, 2023 Age-related macular degeneration (AMD) is a neurodegenerative disease and a leading cause of irreversible vision loss in the developed world. While not classically described as an inflammatory disease, a growing body of evidence has implicated several ...
Karina Ascunce +4 more
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Classification of dry and wet macular degeneration based on the ConvNeXT model
Frontiers in Computational Neuroscience, 2022 PurposeTo assess the value of an automated classification model for dry and wet macular degeneration based on the ConvNeXT model.MethodsA total of 672 fundus images of normal, dry, and wet macular degeneration were collected from the Affiliated Eye ...
Maonian Wu +11 more
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PLoS ONE, 2021 ObjectiveThis study aimed to investigate the risk of Alzheimer's disease among patients with age-related macular degeneration and its association with confounding comorbidities.MethodThis was a population-based, retrospective cohort study.
Li-Yen Wen +9 more
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Juvenile Macular Degenerations [PDF]
Seminars in Pediatric Neurology, 2017 In this article, we review the following 3 common juvenile macular degenerations: Stargardt disease, X-linked retinoschisis, and Best vitelliform macular dystrophy. These are inherited disorders that typically present during childhood, when vision is still developing.
Anne Moskowitz +6 more
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Age Related Macular Degeneration and Total Hip Replacement Due to Osteoarthritis or Fracture: Melbourne Collaborative Cohort Study. [PDF]
PLoS ONE, 2015 Osteoarthritis is the leading cause of total hip replacement, accounting for more than 80% of all total hip replacements. Emerging evidence suggests that osteoarthritis has a chronic inflammatory component to its pathogenesis similar to age-related ...
Elaine W Chong +8 more
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Generative mathematical modelling to demonstrate virtual simulations of neovascular age related macular degeneration. [PDF]
PLoS ONE, 2017 To develop a generative mathematical model of wet age-related macular degeneration (AMD) and model the impact of injections of anti-vascular endothelial growth factor to virtual patients with the condition.We isolated key pathophysiological components of
David Hoyle, Tariq Mehmood Aslam
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