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The Lancet Global Health, 2014 Background: Numerous population-based studies of age-related macular degeneration have been reported around the world, with the results of some studies suggesting racial or ethnic differences in disease prevalence.
Wan Ling Wong, MBiostat +6 more
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Age-Related Macular Degeneration. [PDF]
Nature Reviews Disease Primers, 2021 Age-related macular degeneration (AMD) is the leading cause of legal blindness in the industrialized world. AMD is characterized by accumulation of extracellular deposits, namely drusen, along with progressive degeneration of photoreceptors and adjacent tissues.
C. Thomas, R. Mirza, M. Gill
semanticscholar +3 more sources
Age-related macular degeneration
Clinical Ophthalmology, 2011 Giuseppe Querques¹, Fernando Onofrio Avellis1,2, Lea Querques1,3, Francesco Bandello³, Eric H Souied¹ ¹Service d'Ophtalmologie, Centre Hospitalier Intercommunal Créteil, Université Paris ...
Querques G +4 more
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Sleep, Pain, and Neurodegeneration: A Mendelian Randomization Study
Frontiers in Neurology, 2022 Our aim was to determine whether the genetic liability to sleep and pain-related traits have a causal effect on risk of neurodegeneration in individuals of predominantly European ancestry. We selected five neurodegenerative disorders, namely, age-related
Sandeep Grover +2 more
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Oxidative Stress and Antioxidants in Age-Related Macular Degeneration
Antioxidants, 2023 Oxidative stress plays a crucial role in aging-related eye diseases, including age-related macular degeneration (AMD), cataracts, and glaucoma. With age, antioxidant reparative capacity decreases, and excess levels of reactive oxygen species produce ...
N. Kushwah +4 more
semanticscholar +1 more source
On phagocytes and macular degeneration [PDF]
Progress in Retinal and Eye Research, 2017 Age related macular degeneration (AMD) is a complex multifactorial disease caused by the interplay of age and genetic and environmental risk factors. A common feature observed in early and both forms of late AMD is the breakdown of the physiologically immunosuppressive subretinal environment and the protracted accumulation of mononuclear phagocytes (MP)
Xavier Guillonneau +5 more
openaire +4 more sources
Prevalence of Age-Related Macular Degeneration in the US in 2019.
JAMA ophthalmology, 2022 Importance Age-related macular degeneration (AMD) is a leading cause of vision loss and blindness. AMD prevalence has not been estimated for the US in over a decade and early-stage AMD prevalence estimates are scarce and inconsistently measured ...
David B. Rein +7 more
semanticscholar +1 more source
Innate immune biology in age-related macular degeneration
Frontiers in Cell and Developmental Biology, 2023 Age-related macular degeneration (AMD) is a neurodegenerative disease and a leading cause of irreversible vision loss in the developed world. While not classically described as an inflammatory disease, a growing body of evidence has implicated several ...
Karina Ascunce +4 more
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Autophagy in age-related macular degeneration
Autophagy, 2022 Age-related macular degeneration (AMD) is the leading cause of visual impairment in the aging population with limited understanding of its pathogenesis and a lack of effective treatment.
K. Kaarniranta +5 more
semanticscholar +1 more source
Classification of dry and wet macular degeneration based on the ConvNeXT model
Frontiers in Computational Neuroscience, 2022 PurposeTo assess the value of an automated classification model for dry and wet macular degeneration based on the ConvNeXT model.MethodsA total of 672 fundus images of normal, dry, and wet macular degeneration were collected from the Affiliated Eye ...
Maonian Wu +11 more
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