Results 11 to 20 of about 525,552 (330)

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

open access: yesThe Lancet Global Health, 2014
Background: Numerous population-based studies of age-related macular degeneration have been reported around the world, with the results of some studies suggesting racial or ethnic differences in disease prevalence.
Wan Ling Wong, MBiostat   +6 more
doaj   +2 more sources

Effect of High-Dose Intravitreal Aflibercept, 8 mg, in Patients With Neovascular Age-Related Macular Degeneration

open access: yesJAMA ophthalmology, 2023
This randomized clinical trial assesses the safety and efficacy of aflibercept, 8 mg, in patients with neovascular age-related macular degeneration.
C. Wykoff   +76 more
semanticscholar   +1 more source

Oxidative Stress and Antioxidants in Age-Related Macular Degeneration

open access: yesAntioxidants, 2023
Oxidative stress plays a crucial role in aging-related eye diseases, including age-related macular degeneration (AMD), cataracts, and glaucoma. With age, antioxidant reparative capacity decreases, and excess levels of reactive oxygen species produce ...
N. Kushwah   +4 more
semanticscholar   +1 more source

Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degeneration

open access: yesNeural Regeneration Research, 2023
Age-related macular degeneration is a primary cause of blindness in the older adult population. Past decades of research in the pathophysiology of the disease have resulted in breakthroughs in the form of anti-vascular endothelial growth factor therapies
M. Maurya   +6 more
semanticscholar   +1 more source

Prevalence of Age-Related Macular Degeneration in the US in 2019.

open access: yesJAMA ophthalmology, 2022
Importance Age-related macular degeneration (AMD) is a leading cause of vision loss and blindness. AMD prevalence has not been estimated for the US in over a decade and early-stage AMD prevalence estimates are scarce and inconsistently measured ...
David B. Rein   +7 more
semanticscholar   +1 more source

Autophagy in age-related macular degeneration

open access: yesAutophagy, 2022
Age-related macular degeneration (AMD) is the leading cause of visual impairment in the aging population with limited understanding of its pathogenesis and a lack of effective treatment.
K. Kaarniranta   +5 more
semanticscholar   +1 more source

Lutein and Zeaxanthin and Their Roles in Age-Related Macular Degeneration—Neurodegenerative Disease

open access: yesNutrients, 2022
Lutein and zeaxanthin belong to the xanthophyll family of carotenoids, which are pigments produced by plants. Structurally, they are very similar, differing only slightly in the arrangement of atoms.
M. Mrowicka   +3 more
semanticscholar   +1 more source

The complement system in age-related macular degeneration

open access: yesCellular and Molecular Life Sciences, 2021
Age-related macular degeneration (AMD) is a chronic and progressive degenerative disease of the retina, which culminates in blindness and affects mainly the elderly population.
A. Armento, M. Ueffing, Simon J. Clark
semanticscholar   +1 more source

Age-Related Macular Degeneration: Pathophysiology, Management, and Future Perspectives

open access: yesOphthalmologica, 2021
Among older adults, age-related macular degeneration (AMD) is a prevalent disabling condition that begins as subtle visual disturbances and can progress to permanent loss of central vision.
R. Flores   +4 more
semanticscholar   +1 more source

Multimodal deep learning with feature level fusion for identification of choroidal neovascularization activity in age‐related macular degeneration

open access: yesActa ophthalmologica, 2021
This study aimed to determine the efficacy of a multimodal deep learning (DL) model using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) images for the assessment of choroidal neovascularization (CNV) in ...
Kai Jin   +9 more
semanticscholar   +1 more source

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