New Frontiers in Retina: highlights of the 2020 angiogenesis, exudation and degeneration symposium
We summarize the most important findings presented at the 2020 angiogenesis, exudation and degeneration symposium in five topic areas: (1) epidemiology of retinal vascular disease and macular degeneration; (2) dry AMD and geographic atrophy; (3 ...
Carmen A. Puliafito, Charles C. Wykoff
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Extracellular vesicles as a potential therapeutic for age-related macular degeneration
Age-related macular degeneration is a major global cause of central visual impairment and severe vision loss. With an aging population, the already immense economic burden of costly anti-vascular endothelial growth factor treatment is likely to increase.
Lorraine L. C. Chow, Ben Mead
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Widening use of dexamethasone implant for the treatment of macular edema [PDF]
Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis.
Avitabile T.+9 more
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Recent advances of exosomes in age-related macular degeneration
Exosomes are 30–150 nm extracellular vesicles that are secreted by almost all types of cells. Exosomes contain a variety of biologically active substances, such as proteins, nucleic acids, and lipids, and are important in the intercellular communication ...
Feng Gu, Jiyu Jiang, Peng Sun
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Blindness incidence in Germany - A population-based study from Württemberg-Hohenzollern [PDF]
Few data on the incidence of blindness in Germany are available. We analysed causes of legal blindness for the region Württemberg-Hohenzollern (population 5.5 million) in order to help fill in this gap.
Klauss, V.+4 more
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Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review
Age related macular degeneration is a leading cause of vision loss and an increasing problem of disability throughout the world among adults. That revue covers historical points, risk factors, pathogenesis, classification and current treatment ways of ...
A. N. Kulikov+2 more
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Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]
Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria+5 more
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Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Birke, Kerstin+3 more
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Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration
The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration.
Francisco Bosch-Morell+9 more
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