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Age-Related Macular Degeneration: Pathophysiology, Management, and Future Perspectives
Ophthalmologica, 2021 Among older adults, age-related macular degeneration (AMD) is a prevalent disabling condition that begins as subtle visual disturbances and can progress to permanent loss of central vision.
R. Flores +4 more
semanticscholar +1 more source
Ranibizumab versus verteporfin for neovascular age-related macular degeneration.
New England Journal of Medicine, 2006 BACKGROUND We compared ranibizumab--a recombinant, humanized, monoclonal antibody Fab that neutralizes all active forms of vascular endothelial growth factor A--with photodynamic therapy with verteporfin in the treatment of predominantly classic ...
David M. Brown +7 more
semanticscholar +1 more source
Dietary fatty acids and lipoproteins on progression of age-related macular degeneration [PDF]
, 2017 Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have revealed that changes on certain dietary fatty acids (FAs) could have useful for AMD management.
Abia González, María del Rocío +5 more
core +3 more sources
Reading in the presence of macular disease: a mini-review. [PDF]
, 2020 PurposeReading is vital to full participation in modern society. To millions of people suffering from macular disease that results in a central scotoma, reading is difficult and inefficient, rendering reading as the primary goal for most patients seeking
Chung, Susana TL
core +1 more source
Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]
, 2012 The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Birke, Kerstin +3 more
core +14 more sources
Age-Related Macular Degeneration: Role of Oxidative Stress and Blood Vessels
International Journal of Molecular Sciences, 2021 Age-related macular degeneration (AMD) is a common irreversible ocular disease characterized by vision impairment among older people. Many risk factors are related to AMD and interact with each other in its pathogenesis.
Yue Ruan, Subao Jiang, A. Gericke
semanticscholar +1 more source
Correlation between retinal function and microstructural foveal changes in intermediate age related macular degeneration [PDF]
, 2017 Purpose: To assess foveal microstructural changes influencing retinal sensitivity (RS) and fixation stability using microperimeter MP-1 in intermediate age-related macular degeneration (AMD).
Carnevale, Carmela +3 more
core +2 more sources
mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV
Cell Communication and Signaling, 2019 Background The mechanistic target of rapamycin (mTOR) pathway is a potential target to inhibit pathologic processes in choroidal neovascularization. However, the exact role of mTOR signaling in the development of CNV remains obscure.
Jin Young Yang +7 more
doaj +1 more source
Medicina, 2022 The pathogeneses of age-related macular degeneration (AMD) and age-related hearing impairment are not yet fully understood. If AMD and age-related hearing impairment are correlated, the cause of both may be a result of a common vulnerability.
Marina Istrate +5 more
doaj +1 more source
International Journal of Molecular Sciences, 2021 Neovascular age-related macular degeneration (exudative or wet AMD) is a prevalent, progressive retinal degenerative macular disease that is characterized by neovascularization of the choroid, mainly affecting the elderly population causing gradual ...
Arunbalaji Pugazhendhi +3 more
semanticscholar +1 more source