Results 61 to 70 of about 79,397 (170)

Plant‐Based Biosynthesis of Metal and Metal Oxide Nanoparticles: An Update on Antimicrobial and Anticancer Activity

ChemBioEng Reviews, Volume 11, Issue 6, December 2024.
When it comes to finding novel ways to battle newly developing pathogenic strains and illnesses, nanoparticles are the first line of defense. Plant‐based nanoparticles are showing more significance over chemically or physically synthesized nanoparticles. Several plant species and their constituent parts have found several applications in medicine. They
Shruti Nandkishor Tanwar, Yatish R. Parauha, Yogesh There, Hendrik C. Swart, Sanjay J. Dhoble   +4 more
wiley   +1 more source

Vinca Alkaloids

International Journal of Preventive Medicine, 2013
Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects.
Maryam Moudi, Rusea Go, Christina Yong Seok Yien, Mohd Nazre   +3 more
doaj  

Genome‐based discovery of pachysiphine synthases in Tabernaemontana elegans

The Plant Journal, Volume 120, Issue 5, Page 1880-1900, December 2024.
Significance Statement While pachysiphine is a monoterpene indole alkaloid of high interest and the precursor of an anti‐Alzheimer compound, its biosynthesis involving the epoxidation of tabersonine remains uncharacterized. By sequencing and assembling the genome of Tabernaemontana elegans, we identified two P450s exhibiting a pachysiphine synthase ...
Enzo Lezin, Mickael Durand, Caroline Birer Williams, Ana Luisa Lopez Vazquez, Thomas Perrot, Nicolas Gautron, Julien Pétrignet, Clément Cuello, Hans J. Jansen, Florent Magot, Sarah Szwarc, Pierre Le Pogam, Mehdi A. Beniddir, Konstantinos Koudounas, Audrey Oudin, Benoit St‐Pierre, Nathalie Giglioli‐Guivarc'h, Chao Sun, Nicolas Papon, Michael Krogh Jensen, Ron P. Dirks, Sarah E. O'Connor, Sébastien Besseau, Vincent Courdavault   +23 more
wiley   +1 more source

Explant origin and growth regulators as determinants of callus performance and terpenoid indole alkaloid accumulation in Catharanthus roseus

BMC Plant Biology
Catharanthus roseus (L.) G. Don (Apocynaceae) is a highly important medicinal plant and a valuable source of diverse pharmacologically active compounds particularly anticancer terpenoid indole alkaloids (TIAs), such as catharanthine (CAT), vinblastine ...
Abeer F. Desouky, Salah El-Din El-Assal, Ahmed Abdelsamad, Abdel-Salam Reda, Nancy Danial, Moemen S. Hanafy   +5 more
doaj   +1 more source

A REVIEW OF CATHARANTHUS ROSEUS: AFRICAN MADAGASCAR PERIWINKLE

Abstract: Catharanthus roseus is an evergreen plant that originated from the islands ofMadagascar. It is known for its antitumor, anti-diabetic, and anti-microbial effects. Many famousphytochemicals, such as vincristine and vinblastine, were isolated from the plant.
Belinda A. Amankwah, M. Wiafe-Kwagyan, Aquel Rene Lopez   +2 more
openaire   +1 more source

The evolution and history of Vinca alkaloids: From the Big Bang to the treatment of pediatric acute leukemia

Pediatric Blood &Cancer, Volume 71, Issue 11, November 2024.
Abstract An attractive flower from the island of Madagascar has in part saved the lives of thousands of children with acute lymphoblastic leukemia (ALL). Random mutations and alterations to the genome led to the evolution of genes encoding enzymes, which would provide the periwinkle flower an arsenal of secondary metabolites to survive within the ...
Jeffrey W. Taub, Steven A. Buck, Ana C. Xavier, Holly Edwards, Larry H. Matherly, Yubin Ge   +5 more
wiley   +1 more source

Parallel evolution of methyltransferases leads to vobasine biosynthesis in Tabernaemontana elegans and Catharanthus roseus

Frontiers in Plant Science
Monoterpenoid indole alkaloids (MIA) are one of the largest and most complex alkaloid class in nature, boasting many clinically significant drugs such as anticancer vinblastine and antiarrhythmic ajmaline.
Maisha Farzana, Matthew Bailey Richardson, Daniel André Ramey Deschênes, Zhan Mai, Destiny Ichechi Njoku, Ghislain Deslongchamps, Yang Qu   +6 more
doaj   +1 more source

Jasmonic Acid Effect on the Fatty Acid and Terpenoid Indole Alkaloid Accumulation in Cell Suspension Cultures of Catharanthus roseus

Molecules, 2014
The stress response after jasmonic acid (JA) treatment was studied in cell suspension cultures of Catharanthus roseus. The effect of JA on the primary and secondary metabolism was based on changes in profiles of fatty acids (FA) and terpenoid indole ...
Guitele Dalia Goldhaber-Pasillas, Natali Rianika Mustafa, Robert Verpoorte   +2 more
doaj   +1 more source

Observations sur la zone subdésertique de Madagascar [PDF]

, 1958
Paulian Renaud. Observations sur la zone sub-désertique de Madagascar . In: La Terre et La Vie, Revue d'Histoire naturelle, tome 12, n°4, 1958. pp.
Paulian, Renaud
core   +1 more source

Development of efficient catharanthus roseus regeneration and transformation system using agrobacterium tumefaciens and hypocotyls as explants

BMC Biotechnology, 2012
Background As a valuable medicinal plant, Madagascar periwinkle (Catharanthus roseus) produces many terpenoid indole alkaloids (TIAs), such as vindoline, ajamlicine, serpentine, catharanthine, vinblastine and vincristine et al. Some of them are important
Wang Quan, Xing Shihai, Pan Qifang, Yuan Fang, Zhao Jingya, Tian Yuesheng, Chen Yu, Wang Guofeng, Tang Kexuan   +8 more
doaj   +1 more source