Results 51 to 60 of about 2,477 (190)

Evaluation of Quercus infectoria Phytoconstituents Against Oral Cancer: Network Pharmacology, Docking Simulation, and In Vitro Cytotoxicity Assay

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
This study illustrates a workflow exploring Quercus infectoria against oral cancer through network pharmacology, target prediction, molecular docking, DFT, molecular dynamics, and pathway enrichment. Molecular docking showed strong binding affinities of Nyctanthic acid and β‐Glucogallin with AKT1 and GAPDH, respectively, with the Nyctanthic acid‐AKT1 ...
Priyanka Kamaria, Priyanka Tiwari, Prabitha Prabhakaran, Sakshi Bhardwaj, Krishna Kolachi, Shankar Thapa   +5 more
wiley   +1 more source

Molecular and Biochemical Analysis of a Madagascar Periwinkle Root-Specific Minovincinine-19-Hydroxy-O-Acetyltransferase [PDF]

Plant Physiology, 2001
Abstract The terminal steps in the biosynthesis of the monoterpenoid indole alkaloids vindoline and minovincinine are catalyzed by separate acetyl coenzyme A-dependent O-acetyltransferases in Madagascar periwinkle (Catharanthus roseus G. Don).
P, Laflamme, B, St-Pierre, , De Luca V
openaire   +2 more sources

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.
ABSTRACT Cancer is a major global health concern. Therefore, new treatment options are needed. The phytochemicals have different chemical structures. It also exhibits several other biological activities. Therefore, these compounds are promising anticancer agents. This review aims to identify and assess new candidates for anticancer therapy. Researchers
Alaa A. A. Aljabali, Mohammad A. Obeid, Rasha M. Bashatwah, Esam Qnais, Omar Gammoh, Abdelrahim Alqudah, Vijay Mishra, Yachana Mishra, Mohammad Ahmed Khan, Suhel Parvez, Mohamed El‐Tanani, Taher Hatahet   +11 more
wiley   +1 more source

Exogenous stimulation of Tanacetum vulgare roots with pipecolic acid leads to tissue‐specific responses in terpenoid composition

Plant Biology, Volume 27, Issue 5, Page 891-902, August 2025.
Tissue‐specific changes in terpenoid patterns in tansy are induced by simulated induction of systemic acquired resistance using pipercolic acid. Abstract Tanacetum vulgare L., tansy, is a perennial plant with highly variable terpenoid composition, with mono‐ and sesquiterpenoids being the most abundant.
H. Rahimova, R. Heinen, B. Weber, W. W. Weisser, J.‐P. Schnitzler   +4 more
wiley   +1 more source

Role of LEAFLESS, an AP2/ERF family transcription factor, in the regulation of trichome specialized metabolism

New Phytologist, Volume 247, Issue 2, Page 774-790, July 2025.
Summary Acylsugars, specialized metabolites produced by trichomes of many solanaceous species, provide protection against biotic and abiotic stresses. Many acylsugar metabolic enzymes have been identified; however, regulatory factors remain unknown.
Sabyasachi Mandal, Yohannes H. Rezenom, Thomas D. McKnight   +2 more
wiley   +1 more source

Ultrastructural features of Catharanthus roseus leaves infected with cucumber mosaic virus [PDF]

, 2012
Catharanthus roseus var. rosea, infected with Malaysian isolate of cucumber mosaic virus (CMV-MP), exhibited leaf mosaic, leaf deformation and malformed flowers.
Hashim, Habibuddin, Lau, Wei Hong, Mamat, Mazidah, Tan, Yee How, Yusoff, Khatijah   +4 more
core  

EFFECT OF AUXIN AND CYTOKININ ON VINCRISTINE PRODUCTION BY CALLUS CULTURES OF CATHARANTHUS ROSEUS L. (APOCYNACEAE)

Tropical and Subtropical Agroecosystems, 2009
Callus cultures of Catharanthus roseus L. were established to verify whether they produce vincristine as the intact plant. Different growth regulator combinations were applied to Murashige and Skoog (MS) medium to influence the level of production of ...
Chinnamadasamy Kalidass, Veerabahu Ramasamy Mohan, Arjunan Daniel   +2 more
doaj  

Phylogeny and bioprospecting: The diversity of medicinal plants used in cancer management

PLANTS, PEOPLE, PLANET, Volume 7, Issue 1, Page 147-158, January 2025.
As the second‐leading cause of mortality worldwide, cancer is a major focus of drug discovery research. Traditional plant knowledge can guide the search for undiscovered compounds, but the efficacy of this approach for cancer, a highly complex disease affecting diverse tissues, is unknown.
Jamie B. Thompson, Julie A. Hawkins
wiley   +1 more source

Cell‐type‐aware regulatory landscapes governing monoterpene indole alkaloid biosynthesis in the medicinal plant Catharanthus roseus

New Phytologist, Volume 245, Issue 1, Page 347-362, January 2025.
Summary In plants, the biosynthetic pathways of some specialized metabolites are partitioned into specialized or rare cell types, as exemplified by the monoterpenoid indole alkaloid (MIA) pathway of Catharanthus roseus (Madagascar Periwinkle), the source of the anticancer compounds vinblastine and vincristine. In the leaf, the C.
Chenxin Li, Maite Colinas, Joshua C. Wood, Brieanne Vaillancourt, John P. Hamilton, Sophia L. Jones, Lorenzo Caputi, Sarah E. O'Connor, C. Robin Buell   +8 more
wiley   +1 more source

Plant‐Based Biosynthesis of Metal and Metal Oxide Nanoparticles: An Update on Antimicrobial and Anticancer Activity

ChemBioEng Reviews, Volume 11, Issue 6, December 2024.
When it comes to finding novel ways to battle newly developing pathogenic strains and illnesses, nanoparticles are the first line of defense. Plant‐based nanoparticles are showing more significance over chemically or physically synthesized nanoparticles. Several plant species and their constituent parts have found several applications in medicine. They
Shruti Nandkishor Tanwar, Yatish R. Parauha, Yogesh There, Hendrik C. Swart, Sanjay J. Dhoble   +4 more
wiley   +1 more source