Molecules, 2019 Influenza A viruses leading to infectious respiratory diseases cause seasonal epidemics and sometimes periodic global pandemics. Viral polymerase is an attractive target in inhibiting viral replication, and 4′-ethynyladenosine, which has been ...
Toshifumi Takeuchi +7 more
doaj +1 more source
In vitro potency test for evaluation of Clostridium perfringens type D epsilon toxoid
Arquivos do Instituto BiológicoThe control of enterotoxemia caused by the epsilon toxin, produced by Clostridium perfringenstype D, is based on vaccination with epsilon toxoid. The potency test for this immunogen is conducted using seroneutralization in mice.
Felipe Masiero Salvarini +6 more
doaj +1 more source
CHIMIA, 2004 A selection of the most challenging projects in micro- and nanotechnology tackled at CCS during the last few years are discussed. The ultimate challenge was to localize voltage-gated and ligand-gated ion channels on membranes of living cells by ...
Ursula E. Spichiger-Keller +1 more
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Noncrystalline uric acid inhibits proteoglycan and glycosaminoglycan synthesis in distal tubular epithelial cells (MDCK) [PDF]
, 2010 Hyperuricemia is associated with renal stones, not only consisting of uric acid (UrAc) but also of calcium oxalate (CaOx). Glycosaminoglycans (GAGs) are well-known inhibitors of growth and aggregation of CaOx crystals.
Borges, Fernanda Teixeira +3 more
core +2 more sources
Development of an Enhanced High-Yield Influenza Vaccine Backbone in Embryonated Chicken Eggs
Vaccines, 2023 Vaccination is an efficient approach to preventing influenza virus infections. Recently, we developed influenza A and B virus vaccine backbones that increased the yield of several vaccine viruses in Madin–Darby canine kidney (MDCK) and African green ...
Lizheng Guan +6 more
doaj +1 more source
Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan. [PDF]
PLoS ONE, 2015 A/Narita/1/2009 (A/N) was the first H1N1 virus from the 2009 pandemic (H1pdm) to be isolated in Japan. To better understand and predict the possible development of this virus strain, the effect of passaging A/N was investigated in Madin-Darby canine ...
Akira Ainai +8 more
doaj +1 more source
pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells [PDF]
, 1991 The interaction between late endocytic structures and microtubules in polarized cells was studied using a procedure previously shown to cause microtubule-dependent redistribution of lysosomes in fibroblasts and macrophages (Heuser, J. 1989. J. Cell Biol.
Bacallao, R. +5 more
core +3 more sources
Susceptibility of the C2 canine mastocytoma cell line to the effects of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) [PDF]
, 2009 In the context of bipartite bosonic systems, two notions of classicality of correlations can be defined: P-classicality, based on the properties of the Glauber-Sudarshan P-function; and C-classicality, based on the entropic quantum discord.
Baines, S J +3 more
core +5 more sources
Two DNA aptamers against avian influenza H9N2 virus prevent viral infection in cells. [PDF]
PLoS ONE, 2015 New antiviral therapy for pandemic influenza mediated by the H9N2 avian influenza virus (AIV) is increasingly in demand not only for the poultry industry but also for public health.
Yuewei Zhang +6 more
doaj +1 more source
Characterization of Zn2+ transport in Madin-Darby canine kidney cells
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003 The aim of this study was to characterize the mechanism implicated in Zn(2+) transport in MDCK cells. Trace elements such as Zn(2+), Cd(2+) or Cu(2+) induced MDCK cell depolarization at the micromolar level as demonstrated by bis-oxonol fluorescence and whole-cell patch experiments.
Ducoudret, Olivier +4 more
openaire +3 more sources