Results 21 to 30 of about 32,238 (217)

Ion Channels in Madin-Darby Canine Kidney Cells

Kidney and Blood Pressure Research, 1990
Ion channels in Madin-Darby canine kidney cells serve transepithelial chloride transport and probably cell volume regulation. Three distinct potassium channels and one anion channel have been revealed by patch clamp studies in Madin-Darby canine kidney cells. The potassium channels are activated by an increase in intracellular calcium activity.
F. Lang, F. Friedrich, M. Paulmichl, W. Schobersberger, A. Jungwirth, M. Ritter, M. Steidl, H. Weiss, E. Wöll, E. Tschernko, R. Paulmichl, C. Hallbrucker   +11 more
openaire   +2 more sources

Claudins in the Renal Collecting Duct [PDF]

, 2019
The renal collecting duct fine-tunes urinary composition, and thereby, coordinates key physiological processes, such as volume/blood pressure regulation, electrolyte-free water reabsorption, and acid-base homeostasis.
Leiz, Janna, Schmitt-Ott, Kai M.
core   +1 more source

APOPTOSIS STUDY OF INDONESIAN AVIAN INFLUENZA VIRUS SUBTYPE H5N1 IN MADIN-DARBY CANINE KIDNEY CELLS

Jurnal Kedokteran Hewan, 2017
This study aimed to determine the ability of highly pathogenic avian influenza virus (HPAI) virus subtype H5N1 originated from Indonesia to induce apoptosis in Madin-Darby Canine Kidney (MDCK) cells.
NLP Indi Dharmayanti, Dwi Rillah Ukhti, Farida Syamsiah, Risza Hartawan   +3 more
doaj   +1 more source

Ca2+ movement and apoptosis induced by deltamethrin in Madin–Darby canine kidney canine renal tubular cells

Kaohsiung Journal of Medical Sciences, 2015
This study explored the effect of deltamethrin, a pesticide, on free Ca2+ concentration [Ca2+]i, viability, and apoptosis in Madin–Darby canine kidney (MDCK) canine renal tubular cells.
Fang-Jin Liu, Chiang-Ting Chou, Jin Shiung Cheng, Hong-Tai Chang, Wei-Zhe Liang, Chun-Chi Kuo, Soong-Yu Kuo, Daih-Huang Kuo, Pochuen Shieh, Fang-Rong Chang, Chung-Ren Jan   +10 more
doaj   +1 more source

Identification of glycosylated marker proteins of epithelial polarity in MDCK cells by homology driven proteomics [PDF]

, 2006
BACKGROUND: MDCK cells derived from canine kidney are an important experimental model system for investigating epithelial polarity in mammalian cells. Monoclonal antibodies against apical gp114 and basolateral p58 have served as important tools in these ...
Fullekrug, J., Shevchenko, A., Shevchenko, A., Simons, K.   +3 more
core   +1 more source

Lixazinone Stimulates Mitogenesis of Madin-Darby Canine Kidney Cells

Experimental Biology and Medicine, 2006
Polycystic kidney diseases (PKD) are characterized by excessive proliferation of renal tubular epithelial cells, development of fluid-filled cysts, and progressive renal insufficiency. cAMP inhibits proliferation of normal renal tubular epithelial cells but stimulates proliferation of renal tubular epithelial cells derived from patients with PKD. Madin-
Jingfei, Cheng, Michael A, Thompson, Henry J, Walker, Catherine E, Gray, Gina M, Warner, Wei, Zhou, Joseph P, Grande   +6 more
openaire   +2 more sources

Involvement of Intracellular Ca2+ in the Regulatory Volume Decrease After Hyposmotic Swelling in MDCK Cells

Journal of Pharmacological Sciences, 2007
We examined the source of Ca2+ involved in the volume regulation of Madin-Darby canine kidney (MDCK) cells with confocal microscopy and fluoroprobes. Hyposmosis induced a transient increase in cell volume, as well as cytoplasmic Ca2+, which peaked at 3 ...
Naoko Iida-Tanaka, Iyuki Namekata, Megumi Kaneko, Miku Tamura, Toru Kawanishi, Ryu Nakamura, Koki Shigenobu, Hikaru Tanaka   +7 more
doaj   +1 more source

A conserved LDL-receptor motif regulates corin and CD320 membrane targeting in polarized renal epithelial cells

eLife, 2020
Selective protein distribution on distinct plasma membranes is important for epithelial cell function. To date, how proteins are directed to specific epithelial cell surface is not fully understood. Here we report a conserved DSSDE motif in LDL-receptor (
Ce Zhang, Yue Chen, Shijin Sun, Yikai Zhang, Lina Wang, Zhipu Luo, Meng Liu, Liang Dong, Ningzheng Dong, Qingyu Wu   +9 more
doaj   +1 more source

Substrate Stiffness Determines the Establishment of Apical-Basal Polarization in Renal Epithelial Cells but Not in Tubuloid-Derived Cells

Frontiers in Bioengineering and Biotechnology, 2022
Mechanical guidance of tissue morphogenesis is an emerging method of regenerative medicine that can be employed to steer functional kidney architecture for the purpose of bioartificial kidney design or renal tissue engineering strategies.
Maria J. Hagelaars, Maria J. Hagelaars, Fjodor A. Yousef Yengej, Fjodor A. Yousef Yengej, Marianne C. Verhaar, Maarten B. Rookmaaker, Sandra Loerakker, Sandra Loerakker, Carlijn V. C. Bouten, Carlijn V. C. Bouten   +9 more
doaj   +1 more source

Urinary secretion and extracellular aggregation of mutant uromodulin isoforms [PDF]

, 2012
Uromodulin is exclusively expressed in the thick ascending limb and is the most abundant protein secreted in urine where it is found in high-molecular-weight polymers.
Amoroso A, Bachi A, Benoni S, Bernascone I, Campo A, Caridi G, Cattaneo A, De Marchi M, Ghiggeri GM, Giachino D, Izzi C, Murtas C, Rampoldi L, Santambrogio S, Schaeffer C, Scolari F, Trudu M   +16 more
core   +1 more source