Results 51 to 60 of about 32,238 (217)

Microlith Formation In Vitro by Madin Darby Canine Kidney (MDCK) Cells [PDF]

International Journal of Urology, 1996
Background: The mechanism of renal stone genesis as well as the location of stone crystal formation in the kidney remains unclear. Possible sites of stone generation are either in the tubular lumen or tubular cell.Methods: We cultured Madin Darby canine kidney (MDCK), LLC‐PK1 and Magen Krebs Niigata‐28 (MKN‐28) cells in DMEM + 10% FBS medium in a well ...
S, Kageyama, Y, Ohtawara, K, Fujita, T, Watanabe, T, Ushiyama, K, Suzuki, Y, Naito, K, Kawabe   +7 more
openaire   +2 more sources

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Cell membrane disruption stimulates cAMP and Ca2+ signaling to potentiate cell membrane resealing in neighboring cells

Biology Open, 2017
Disruption of cellular plasma membranes is a common event in many animal tissues, and the membranes are usually rapidly resealed. Moreover, repeated membrane disruptions within a single cell reseal faster than the initial wound in a protein kinase A (PKA)
Tatsuru Togo
doaj   +1 more source

Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. [PDF]

, 1990
We studied the cell-surface delivery pathways of newly synthesized membrane glycoproteins in MDCK cells and for this purpose we characterized an endogenous apical integral membrane glycoprotein.
Le Bivic, A, Mostov, K, Rodriguez-Boulan, E, Sambuy, Y   +3 more
core  

MAL/VIP17, a new player in the regulation of NKCC2 in the kidney [PDF]

, 2010
The renal-specific Na+-K+-2Cl- cotransporter (NKCC2) is the major salt transport pathway of the apical membrane of the mammalian thick ascending limb of Henle's loop.
Basco, Davide, Caplan, Michael J., Carmosino, Monica, Forbush, Biff, Procino, Giuseppe, Rizzo, Federica, Schaeren-Wiemers, Nicole, Svelto, Maria, Valenti, Giovanna   +8 more
core   +2 more sources

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

Multigram Scale Synthesis and Anti-Influenza Activity of 3-Indoleacetonitrile Glucosides

Natural Product Communications, 2020
Indole-3-acetonitrile-6- O-β - d -glucopyranoside 1 is a simple alkaloid with anti-influenza A virus activity extracted from Radix isatidis . Herein, a concise and practical total synthetic route of 1 was presented, starting from 6-benzyloxyindole on a ...
Jianghong Dong, Fengmei Yan, Shuang Li, Zewen Li, Yuanhang Qin   +4 more
doaj   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, Volume 13, Issue 26, 8 May 2026.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Intranasal vaccination with an engineered influenza virus expressing the receptor binding subdomain of botulinum neurotoxin provides protective immunity against botulism and influenza

Frontiers in Immunology, 2015
Influenza virus is a negative, segmented RNA virus without DNA intermediate. This makes it safer as a vaccine delivery vector than most DNA viruses that have potential to integrate their genetic elements into host genomes.
Junwei eLi, Diana eDiaz-Arévalo, Yanping eChen, Mingtao eZeng   +3 more
doaj   +1 more source

Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density

Nature Communications, 2023
Changes in tissue geometry during developmental processes are associated with collective migration of cells. Recent experimental and numerical results suggest that these changes could leverage on the coexistence of nematic and hexatic orientational order
Julia Eckert, Benoît Ladoux, René-Marc Mège, Luca Giomi, Thomas Schmidt   +4 more
doaj   +1 more source