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Genomic Characterization of a Slow/Low Maedi Visna Virus

Virus Genes, 2004
The complete genomic sequence of a sheep lentivirus isolate that presents a slow/low phenotype in vitro has been determined. The virus, designated P1OLV, was isolated from lung cells of a naturally infected sheep in Portugal. Three overlapping DNA fragments amplified by PCR, and encompassing the entire viral genome were cloned and sequenced.
Sílvia C, Barros   +5 more
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Investigations of a flock heavily infected with maedi-visna virus

Veterinary Record, 1983
Following the discovery that a flock of sheep in England was infected with the virus of maedi-virus, several seropositive sheep were brought to the Central Veterinary Laboratory and kept isolated and under observation for up to three years before being further examined at necropsy.
L M, Markson, J B, Spence, M, Dawson
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The demonstration of maedi/visna virus in sheep in Great Britain

Veterinary Record, 1979
A virus indistinguishable from that causing maedi/visna has been isolated from a sheep flock in Great Britain. The virus was identified in cell cultures using immunofluorescent and electron microscopical techniques. The complement fixation test and the agar gel immunodiffusion test were used to assess the proportion of serological reactors within the ...
M, Dawson   +6 more
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Development of a candidate DNA vaccine against Maedi-Visna virus

Veterinary Immunology and Immunopathology, 2007
DNA vaccine candidates against Maedi-Visna virus (MVV) infection in ovines were developed as an alternative to conventional vaccines. Candidates were constructed by cloning genes encoding the MVV gag polyprotein and gag proteins p16 and p25 fused to a beta-galactosidase reporter in a plasmid backbone.
Ana M, Henriques   +3 more
openaire   +2 more sources

Evidence for Recombination in the Envelope Gene of Maedi-visna Virus

Virus Genes, 2003
Frequent recombination occurs during replication in all retroviruses examined. This increases the genetic variation in the retroviral population and may be of importance in the evolution of the virus. Maedi-visna virus (MVV), a retrovirus of sheep, has a highly variable envelope gene.
openaire   +2 more sources

A study on lymphocyte activation in maedi-visna virus induced pneumonia

Veterinary Immunology and Immunopathology, 1995
The stage of activation of bronchoalveolar lavage fluid (BALF) lymphocytes and peripheral blood lymphocytes (PBL) from maedi-visna virus (MVV) infected (n = 7) and control (n = 7) sheep was investigated by assessing four parameters of lymphocyte activation; lymphocyte size and complexity, loss of CD5+ T cells, expression of cell surface interleukin-2 ...
I, Begara   +5 more
openaire   +2 more sources

Clinicopathological investigation of primary, uncomplicated maedi-visna virus infection

Veterinary Record, 1992
Maedi-visna virus infection in a flock of sheep in Scotland was associated with respiratory disease, neurological disease, mastitis and lameness. The major clinical signs were dyspnoea (particularly on exercise), progressive fore- and hindlimb ataxia and balance defects, mammary induration and multilimb lameness, occasionally with enlarged carpal ...
N J, Watt   +5 more
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Detection of Maedi-Visna Virus in the Kidneys of Naturally Infected Sheep

Journal of Comparative Pathology, 2006
Infections with maedi-visna virus (MVV) cause progressive inflammation in different organs, mainly the lung, mammary gland, brain and joints. The aim of the present study was to investigate whether the kidney represents a viral target in natural MVV infection. For this, kidney samples from 13 sheep naturally infected with MVV were examined by histology,
K, Angelopoulou   +2 more
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Isolation of a glycoprotein and two structural proteins of maedi-visna virus

Virology, 1979
Abstract A viral glycoprotein of Maedi-Visna virus was purified by affinity chromatography, rate zonal centrifugation, and isoelectric focusing. Furthermore, two structural proteins of the virus were purified by isoelectric focusing and Sephadex gel filtration.
M, Bruns, B, Frenzel
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Neurotoxic mechanisms of transactivating protein Tat of Maedi-Visna virus

Neuroscience Letters, 1995
Infection by lentiviruses such as human immunodeficiency virus (HIV) and Maedi-Visna virus (MVV) is associated with neurodegenerative disorders. We have investigated the neurotoxic mechanisms of a synthetic peptide of transactivating protein tat of MVV in striatal neuronal cultures.
Strijbos, P. J L M   +4 more
openaire   +3 more sources

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