Results 171 to 180 of about 2,017 (204)
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The demonstration of maedi/visna virus in sheep in Great Britain
Veterinary Record, 1979A virus indistinguishable from that causing maedi/visna has been isolated from a sheep flock in Great Britain. The virus was identified in cell cultures using immunofluorescent and electron microscopical techniques. The complement fixation test and the agar gel immunodiffusion test were used to assess the proportion of serological reactors within the ...
M, Dawson +6 more
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A study on lymphocyte activation in maedi-visna virus induced pneumonia
Veterinary Immunology and Immunopathology, 1995The stage of activation of bronchoalveolar lavage fluid (BALF) lymphocytes and peripheral blood lymphocytes (PBL) from maedi-visna virus (MVV) infected (n = 7) and control (n = 7) sheep was investigated by assessing four parameters of lymphocyte activation; lymphocyte size and complexity, loss of CD5+ T cells, expression of cell surface interleukin-2 ...
I, Begara +5 more
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Clinicopathological investigation of primary, uncomplicated maedi-visna virus infection
Veterinary Record, 1992Maedi-visna virus infection in a flock of sheep in Scotland was associated with respiratory disease, neurological disease, mastitis and lameness. The major clinical signs were dyspnoea (particularly on exercise), progressive fore- and hindlimb ataxia and balance defects, mammary induration and multilimb lameness, occasionally with enlarged carpal ...
N J, Watt +5 more
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Isolation of a glycoprotein and two structural proteins of maedi-visna virus
Virology, 1979Abstract A viral glycoprotein of Maedi-Visna virus was purified by affinity chromatography, rate zonal centrifugation, and isoelectric focusing. Furthermore, two structural proteins of the virus were purified by isoelectric focusing and Sephadex gel filtration.
M, Bruns, B, Frenzel
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Detection of Maedi-Visna Virus in the Kidneys of Naturally Infected Sheep
Journal of Comparative Pathology, 2006Infections with maedi-visna virus (MVV) cause progressive inflammation in different organs, mainly the lung, mammary gland, brain and joints. The aim of the present study was to investigate whether the kidney represents a viral target in natural MVV infection. For this, kidney samples from 13 sheep naturally infected with MVV were examined by histology,
K, Angelopoulou +2 more
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Breed susceptibility to ovine progressive pneumonia (maedi/visna) virus
Veterinary Microbiology, 1986In this retrospective study of breed differences in susceptibility to disease caused by ovine progressive pneumonia (OPP) virus, 29 Border Leicester sheep were compared with 46 Columbia sheep. As judged by frequency and severity of clinical signs and lesions attributable to the infection, Border Leicester sheep were markedly more susceptible than ...
R C, Cutlip +3 more
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Development of a candidate DNA vaccine against Maedi-Visna virus
Veterinary Immunology and Immunopathology, 2007DNA vaccine candidates against Maedi-Visna virus (MVV) infection in ovines were developed as an alternative to conventional vaccines. Candidates were constructed by cloning genes encoding the MVV gag polyprotein and gag proteins p16 and p25 fused to a beta-galactosidase reporter in a plasmid backbone.
Ana M, Henriques +3 more
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Evidence for Recombination in the Envelope Gene of Maedi-visna Virus
Virus Genes, 2003Frequent recombination occurs during replication in all retroviruses examined. This increases the genetic variation in the retroviral population and may be of importance in the evolution of the virus. Maedi-visna virus (MVV), a retrovirus of sheep, has a highly variable envelope gene.
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Expression of the SU glycoprotein of maedi visna virusin baculovirus
Archives of Virology, 1997The envelope glycoprotein, gp 135, of the ovine lentivirus maedi visna virus is the main target for a specific antibody response in vivo, however, little is known about the specific regions of gp 135 which elicit this response. Research on the function of gp 135 has been hampered by the lack of reagents to study such structure/function relationships ...
P, Carter, R G, Dalziel
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Immune responses to maedi-visna virus
2018Maedi-visna infected sheep develop detectable levels of anti-viral antibody by 4-6 weeks after experimental infection. These antibodies are directed against the envelope and core structural proteins of the virus and initially are of the IgM isotype, but later switch to IgG. These IgG anti-visna antibodies are restricted to the IgGj subclass.
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