Results 81 to 90 of about 764,832 (295)

Contenidos Filosóficos y Evaluación en Filosofía: una Apuesta para la Escuela Contemporánea

Praxis & Saber
El artículo presenta los resultados parciales de una investigación que indaga sobre Discursos y prácticas sobre contenidos filosóficos y evaluación en filosofía en la enseñanza de la filosofía y su relación con la formación de estudiantes en ...
Oscar Pulido Cortés, Jorge Anibal Rojas , Deiscy Soraya Montaña   +2 more
doaj   +1 more source

Gran Telescopio Canarias observations of an overdense region of Lyman alpha emitters at z=6.5 [PDF]

, 2017
We present the results of our search near the end of the Reionization Epoch for faint galaxies. This has been done using very deep OSIRIS images obtained at the Gran Telescopio Canarias (GTC).
Gallego Maestro, Jesús, otros, ...
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Integration Policies and cultural rights: Immigration Programmes in the Government of Andalucia [PDF]

, 2010
Se parte del análisis de las limitaciones del gobierno andaluz en el proceso de integración de inmigrantes dado el contexto de discriminación institucionalizada que se ejerce en los niveles estatal y europeo. El gobierno andaluz parte del individualismo
Moreno Maestro, Susana
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Maestro seni tradisi [PDF]

, 2008
Maestro Seni Tradisi Indonesia adalah tokoh-tokoh seni tradisional Indonesia yang terpilih berdasarkan hasil pengamatan dan survei di lapangan serta hasil penilaian dan diskusi mendalam oleh Tim Penilai yang terdiri atas akademisi, pakar, budayawan ...
Hartono, Yusuf Susilo, Hastuti, Rita Sri, Nurhan, Kenedi   +2 more
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Scheduling spacecraft operations [PDF]

A prototype scheduling system named MAESTRO currently under development is being used to explore possible approaches to the spacecraft operations scheduling problem.
Britt, Daniel L., Geoffroy, Amy L., Gohring, John R., Schaefer, Philip R.   +3 more
core   +1 more source