Results 61 to 70 of about 31,301 (262)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Revista Española de PedagogíaLa calidad educativa es una integralidad del currículo en la escuela, ya que abarca todos los aspectos de la vida escolar y su contexto. Esto implica orientar los principios e ideales hacia el centro del conocimiento. En nuestra realidad escolar, uno de
Nelson Eduardo Cardona Muñoz
doaj
Pensamiento Palabra y Obra, 2018 Este art.culo es el resultado de un proceso de investigaci.n que inicio en el a.o 2010 en la comuna trece de Cali, en el barrio los lagos I, con el grupo folclórico Integración Pacífico.
John Alexis Rengifo Carpintero +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Problems and notes for a critical history of schooling
Avances en Supervisión Educativa, 2013 Escribir un artículo sobre la escolarización desde una perspectiva histórica y crítica es un reto sugerente, pero bastante ambicioso. Por ello es preciso imponer desde el principio unos límites realistas y hacer un ejercicio de modestia (también podría ...
Julio Mateos Montero
doaj
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
"Maestro e inventor". Vivencias de un maestro nacional
Cabás, 2011 "Maestro e invertor". Vivencias de un maestro nacional.
José Luis Calderón Fernández
doaj