Results 61 to 70 of about 148,513 (305)

Entrevista maestro Alexander Amézquita

open access: yes, 2019
Maestro en Artes musicales con énfasis en Arreglos y Composición de la facultad de artes de la Universidad Distrital, saxofonista y Director coral y orquestal.
Carlos, Edwin
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Sentipensando la Esperanza Pedagógica. Maestras y maestros sureando, de pie y resistiendo

open access: yesTrenzar, 2020
La presente reflexión nace del diálogo entre dos maestros sentipensantes, quienes creen en la esperanza del cambio y de cómo ésta se configura en punto de partida para generar procesos transformativos con otras y otros ante una educación que se nos ...
Deyby Espinosa Gómez   +1 more
doaj  

Dinamización de la asignatura de Fotónica del Grado en Física

open access: yes, 2023
Memoria final del proyecto de innovación docente Convocatoria 2022/2023 Nº de proyecto: 76 Dinamización de la asignatura de Fotónica del Grado en Física.
Martínez Matos, Óscar   +5 more
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Mario Emilio Dihigo Llanos: legado y vigencia

open access: yesRevista Médica Electrónica, 2015
En 2014 se cumplieron 129 años del nacimiento del Dr. Mario Emilio Dihigo Llanos (1895-1976), reconocido médico y profesor. Con el objetivo de rendirle un merecido homenaje, se realizó este trabajo.
Miriam Gloria Elizarde Gálvez   +3 more
doaj  

Francesco Venezia, maestro di spazi e affioramenti di memoria.

open access: yes, 2011
L'architettura e la filosofia di Francesco Venezia, maestro di spazi e affioramenti di ...
LENCI, Ruggero
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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