Results 41 to 50 of about 113,829 (310)

El estatuto del maestro

open access: yesRevista Colombiana de Educación, 2014
En este artículo se discute la intersección de algunos elementos para pensar el estatuto del maestro hoy, a propósito de la tan anhelada búsqueda de la excelencia docente.
Pilar Méndez
doaj   +1 more source

El maestro en la prensa colombiana de finales del siglo XX (1985-1994)

open access: yesPráxis Pedagógica, 2021
Este artículo derivado de la investigación “Imaginarios sociales sobre la figura del maestro (1985-1994)” realiza, a través de un acercamiento documental a las publicaciones de la Casa Editorial El Tiempo, para el periodo mencionado, una descripción de ...
Susana Ramírez-Serna
doaj   +1 more source

Modelos de Maestro para un " Maestro Modelo" [PDF]

open access: yesClío & Asociados. La historia enseñada, 2005
La hipótesis sostiene asimismo que, lejos de constituir un imaginario de baja o nula operatividad institucional, los rasgos del modelo de docente que aparecen en los discursos son la emergencia lingüística de toda una serie de prácticas que tienen aún extraordinaria vigencia en el ámbito escolar.
Maristany, José Javier   +3 more
openaire   +4 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Cosmic rays: direct measurements [PDF]

open access: yes, 2015
This paper is based on the rapporteur talk given at the 34$^th$ International Cosmic Ray Conference (ICRC), on August 6$^th$, 2015. The purpose of the talk and paper is to provide a summary of the most recent results from balloon-borne and space-based ...
Paolo Maestro, Maestro, Paolo
core   +1 more source

Tensiones y agencia en la escuela pública hoy

open access: yesIE Revista de Investigación Educativa de la REDIECH, 2019
El presente artículo es un ejercicio argumentativo en el marco de la investigación “La función social de los maestros/as de secundaria en la escuela pública de Bogotá”.
Ana María Guzmán Mora
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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