Results 21 to 30 of about 31,301 (262)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Atypical diffuse white matter changes in a patient with anti-GQ1B spectrum disorder: A case report

Radiology Case Reports
This case report has the objective to describe clinical presentation, imaging findings and management of a patient with a GQ1B related disorder, presenting with features involving the peripheral nervous system (autonomic dysfunction, acute flaccid ...
Ana Luisa Faria Donadon, MD, Matheus Alves da Silva, MD, Amanda Miranda de Mendonça, MD, Rafael Bragança Rodrigues Matias, MD, Eduardo Mesquita de Souza, MD, Alex Araújo Fernandes, MD, Matheus Luís Braga Munareto, MD, Andre Luiz Guimaraes de Queiroz, MD, Karla Danielle Ferreira Lima, MD, Danielly Viana Monteiro Santos, MD, Victor Hugo Rocha Marussi, MD, Alex Machado Baeta, PhD   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Sebastián de Vivanco: El último gran maestro de música del Siglo de Oro en Salamanca

Studia Historica: Historia Moderna, 2023
En homenaje al 400 aniversario de la muerte del músico y docente Sebastián de Vivanco, se reivindicará su figura completando algunos datos biográficos y de su labor en torno a su etapa fundamental en Salamanca; una ciudad que venía de experimentar un ...
Javier Cruz Rodríguez
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Sobre el maestro, el entrenamiento, el cuidado de sí y el decir veraz

Praxis & Saber, 2019
En estas notas editoriales se hace un reconocimiento al maestro como forma y sujeto de la educación contemporánea que sobrevive a los embates de la mercantilización y el mercado que circula en la sociedad —en términos generales— y en la educación —como ...
Oscar Pulido Cortés
doaj   +1 more source

La vocación en la identidad del maestro de Educación Infantil: una revisión de la última década

Revista Electrónica en Educación y Pedagogía, 2020
Este trabajo constituye una aproximación al papel que juega la vocación docente en el proceso de construcción de la identidad profesional del maestro/a de Educación Infantil. Para ello, se ha realizado una revisión sistemática de la producción científica
Eduardo Romero Sánchez, Laura Gil Martínez, Esperanza Almagro Durán   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Maestros of anesthesia

eLife
Microglia regulate anesthesia by altering the activity of neurons in specific regions of the brain via a purinergic receptor.
Romeesa Khan, Rodney M Ritzel
openaire   +4 more sources