Results 51 to 60 of about 29,084 (308)

El origen de la universidad Incluyente en México: Su evolución y retos

Revista Biológico Agropecuaria Tuxpan, 2020
Desde el desarrollo de los tiempos, la educación ha ido evolucionando, ya que esto ha traído la inclusión de alumnos con diversas variantes en su desarrollo, y con esto podemos ver que en México, ha sido una continua inclusión dentro de las formas de ...
Marisa Aideé Ariaza Santillán, Marisol Priscila Palafox Bolívar, Octavio Torres López, Liliana Álvarez Loya, José Emilio Méndez González   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

El jaramillismo

Voces de la educación, 2018
El jaramillismo fue y es, puesto que aún existen decenas o centenas de labriegos que se reclaman jaramillistas, un movimiento social, prioritariamente agrario, que se ubica específicamente en el estado de Morelos y partes de Puebla y Guerrero.
Enrique Ávila Carrillo
doaj  

Desafíos para la inclusión en el aula

Acción y Reflexión Educativa
Esta investigación tiene la intención de identificar cuáles son los desafíos a los que se enfrentaron los docentes en formación, para desarrollar una práctica inclusiva dentro del aula, durante sus prácticas profesionales.
Sergio Hugo Hernández Belmonte
doaj   +1 more source

State of the educational research project: “the efficacy and the quality of skill acquisition in rural education: is this model transferable to different types of schools?”

Educação (Santa Maria. Online), 2012
The paper presents a State of the Art regarding the research project “the efficacy and the quality of skill acquisition in rural education: is this model transferable to different types of schools?” (EDU2009-13460, Subprograma EDUC).
Laura Domingo, Roser Boix Tomàs, Pierre Champollion   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

La presencia del normalismo en la Historia contemporánea de nuestro país

Voces de la educación, 2017
En este artículo, trató de explicar el largo y contradictorio caminar de los profesores de enseñanza básica, desde que México obtiene su independencia de España.
Enrique Ávila Carrillo
doaj