Results 51 to 60 of about 101,022 (282)
Voces de la educación, 2018 El jaramillismo fue y es, puesto que aún existen decenas o centenas de labriegos que se reclaman jaramillistas, un movimiento social, prioritariamente agrario, que se ubica específicamente en el estado de Morelos y partes de Puebla y Guerrero.
Enrique Ávila Carrillo
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2023 En estos turbulentos días se escuchan voces encontradas que buscan soluciones. Entre esas voces aparecen las de los maestros quienes, cada día, toman más importancia en nuestra sociedad.
Huertas, Rodrigo +4 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Educação (Santa Maria. Online), 2012 The paper presents a State of the Art regarding the research project “the efficacy and the quality of skill acquisition in rural education: is this model transferable to different types of schools?” (EDU2009-13460, Subprograma EDUC).
Laura Domingo +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
La presencia del normalismo en la Historia contemporánea de nuestro país
Voces de la educación, 2017 En este artículo, trató de explicar el largo y contradictorio caminar de los profesores de enseñanza básica, desde que México obtiene su independencia de España.
Enrique Ávila Carrillo
doaj
Investigaciones Geográficas, 2012 En este documento se exponen los conceptos básicos que ayudan a entender otra forma de gestionar la Zona Metropolitana del Valle de México (ZMVM). Con el objetivo de descifrar el comportamiento de los agentes que intervienen en la ZMVM se abordan los ...
Jesús Rodríguez Rodríguez +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source