Results 111 to 120 of about 183,801 (267)
A variance components factor model for genetic association studies: a Bayesian analysis.
, 2010 Studies of gene-trait associations for complex diseases often involve multiple traits that may vary by genotype groups or patterns. Such traits are usually manifestations of lower-dimensional latent factors or disease syndromes.
Nonyane, BAS, Whittaker, JC
core +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton +217 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Penggunaan Cendawan Mikoriza Arbuskula (Cma) Untuk Mengendalikan Fusarium Oxysporum F.sp. Cubense Dan Nematoda Radopholus Similis Pada Tanaman Pisang Barangan (Musa Paradisiaca L.) Di Rumah Kaca [PDF]
, 2013 The use of mycorrhizal arbuscula fungi (MAF) to control the Fusarium oxysporum f.sp.cubense and Radopholus similis on Barangan banana (Musa paradisiaca L.) in glasshouse.The research was to knew the effectivity of MAF in controling Fusarium wilt and R ...
Ambarwulan, R. (Rini) +2 more
core
Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort
Annals of Neurology, EarlyView.Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov +42 more
wiley +1 more source
Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?
Annals of Neurology, EarlyView.Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano +20 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective SOD1 is the second most frequently mutated gene in European patients with amyotrophic lateral sclerosis (ALS). Given the recent authorization of SOD1‐targeted antisense oligonucleotides for SOD1‐ALS, prompt screening for SOD1 mutations in patients with ALS patients is highly recommended.
Delia Gagliardi +9 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Dicynodonts (Anomodontia: Dicynodontia) were one of the main groups of terrestrial tetrapods in Permian and Triassic faunas. In Brazil, the genus Dinodontosaurus is one of the most common tetrapod taxon in the Triassic Santa Maria Supersequence. This genus has a complex taxonomic history and is represented in the Triassic of both Argentina and
Julia Lara Rodrigues de Souza +5 more
wiley +1 more source
Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak
Animal Research and One Health, EarlyView.Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan +15 more
wiley +1 more source
Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep
Animal Research and One Health, EarlyView.Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang +3 more
wiley +1 more source