Results 121 to 130 of about 103,106 (291)

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu   +9 more
wiley   +1 more source

Rare genetic variation in adults with surgically treated temporal lobe epilepsy: An exome sequencing study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To determine the frequency of monogenic variants and pathogenic copy number variants (CNVs) in adults with surgically treated temporal lobe epilepsy (TLE). Methods We performed exome sequencing (ES), including CNV analysis, in 45 adults with TLE who had previously undergone epilepsy surgery.
Antonia P. Pirker   +12 more
wiley   +1 more source

Air pollution exposure during training impairs performance in Thoroughbred racehorses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ambient air pollution contributes substantially to human morbidity and mortality, and athletes are recognised as a particularly vulnerable group. However, little is known about the impact of air pollution on equine athletes. Objectives To explore the relationship between air pollution exposure during the pre‐competition training ...
Danielle Scott   +4 more
wiley   +1 more source

The Turkish Version of Multidimensional Assessment of Fatigue and Fatigue Severity Scale is Reproducible and Correlated With Other Outcome Measures in Patients With Systemic Sclerosis

open access: yesThe Turkish Journal of Gastroenterology, 2016
Objectives: This study aims to evaluate the reproducibility of Turkish versions of multidimensional assessment of fatigue (MAF) and fatigue severity scales (FSS) and the relationship between health related quality of life, disability, and psychological ...
Kevser GÖK   +3 more
doaj  

Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan   +4 more
wiley   +1 more source

MAF induction by Ebolavirus.

open access: yes
We studied Ebolavirus infection transcriptome-wide across multiple systems to monitor transcriptional dynamics following controlled infection. We report here induction of the nuclear factor MAF in cells following infection with Ebolavirus: in primary human hepatocytes, and in hepatocytes derived from induced pluripotent stem cells.
openaire   +1 more source

Using a wearable electrocardiogram (ECG) patch adapted for 7‐day monitoring in the horse

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Arrhythmias can cause poor performance and sudden death in horses. Long‐term (>24 h) electrocardiogram (ECG) monitoring has been used to identify arrhythmias in humans and is superior to short‐term monitoring for transient arrhythmia detection. Televet is the current equine gold‐standard ECG device. The Cardea SOLO™ (CS) is a single‐
Tatiana Delecave Dias   +3 more
wiley   +1 more source

Targeting the Liquid–Liquid Separation Region of c‐Maf for Treating Chromosomal Translocations in Multiple Myeloma

open access: yesMedComm
Multiple myeloma (MM), as an incurable hematologic malignancy, is driven by chromosomal translocations. Recent research suggests that targeting phase separation may offer a new therapeutic vulnerability for MM.
Ze Wang   +11 more
doaj   +1 more source

Role of MAF in bone metastasis [PDF]

open access: yes, 2017
The identification of genes that mediate metastasis is pivotal to better understand the mechanism, to develop novel drugs and to stratify patients with highest risk and consecutively administrate them preventive treatments.
Bellmunt i Tarragó, Anna
core  

Monitoring and assessment for obstructive sleep apnea

open access: yesFlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu   +6 more
wiley   +1 more source

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