Results 81 to 90 of about 728,274 (341)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Clarifying the influence of albumin on the initial stages of magnesium corrosion in Hank's balanced salt solution

open access: yesJournal of Magnesium and Alloys, 2021
The corrosion behavior of Mg, a promising biodegradable metallic material, in protein-containing pseudophysiological environment is still not fully understood.
Di Mei   +3 more
doaj  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Magnesium [PDF]

open access: yesJournal of Pain and Symptom Management, 2013
Vincent, Crosby   +4 more
openaire   +3 more sources

The role and significance of Magnesium in modern day research-A review

open access: yesJournal of Magnesium and Alloys, 2021
S. V. Prasad   +5 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Enhanced mechanical properties and degradation rate of Mg–Ni–Y alloy by introducing LPSO phase for degradable fracturing ball applications

open access: yesJournal of Magnesium and Alloys, 2020
In this work, as-cast Mg–Ni–Y alloys were proposed to develop a feasible material for fracturing balls, and their mechanical performance and corrosion behavior were systematically investigated.
Jingfeng Wang   +8 more
doaj  

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