Results 91 to 100 of about 5,297,615 (283)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Langevin theory of absorbing phase transitions with a conserved magnitude

open access: yes, 2003
The recently proposed Langevin equation, aimed to capture the relevant critical features of stochastic sandpiles, and other self-organizing systems is studied numerically.
Constantino A. da Silva Santos   +12 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Medication Administration Errors and Associated Factors Among Nurses

open access: yesInternational Journal of General Medicine, 2020
Dejene Tsegaye,1 Girma Alem,1 Zenaw Tessema,2 Wubet Alebachew3 1Department of Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos,
Tsegaye D   +3 more
doaj  

ABOUT A POSSIBLE CONNECTION BETWEEN EARTHQUAKES AND LUNAR-SOLAR GRAVITY VARIATIONS

open access: yesИзвестия высших учебных заведений: Геология и разведка, 2018
A possible correlation between the destructive earthquakes of magnitude M = 7 and above and luni-solar gravity variations between 1975 and 2015 has been analyzed.
Yu. V. Antonov
doaj   +1 more source

On the Color Magnitude Relation of Early-type Galaxies

open access: yes, 2009
In this letter we present a study of the color magnitude relation of 468 early-type galaxies in the Virgo Cluster with Sloan Digital Sky Survey imaging data.
Adelman-McCarthy   +29 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Comparative Analysis Of Accelerometer Sensor And Piezoelectric Sensor Capabilities In The Early Warning System Earthquake Disaster

open access: yesJournal of Electrical Engineering and Computer
An earthquake is a vibration or shock caused by a sudden release of energy from within the earth, which produces seismic waves. The Indonesian region is currently vulnerable to volcanic and tectonic earthquakes due to the Pacific Ring of Fire, where the ...
Yoses Manuel   +2 more
doaj   +1 more source

MATHEMATICAL MODEL FOR CALCULATING ENERGY CLASS, INTENSITY AND MAGNITUDE OF THE EARTHQUAKE REAL TIME

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2016
The mathematical dependence, allowing a nomogram based on T.G. Rautian calculates real-time energy class, magnitude and intensity of earthquakes.
G. K. Aslanov   +3 more
doaj   +1 more source

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