Results 61 to 70 of about 652,724 (310)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Efficacy and safety of Ixazomib-based maintenance therapy after autologous hematopoietic stem cell transplantation in multiple myeloma patients: a retrospective analysis

Frontiers in Medicine
IntroductionThe therapeutic standard for post-autologous stem cell transplantation (ASCT) maintenance in multiple myeloma (MM) is evolving, with daratumumab-based regimens emerging as highly effective. However, access to such therapies remains limited in
Mengyuan Chen, Gang Chen, Jianli Xu, Kaile Zhang, Ruixue Yang, Chunxia Han, Jia Hou, Ming Jiang, Hailong Yuan   +8 more
doaj   +1 more source

Lower Choline-Containing Metabolites/Creatine (Cr) Rise and Failure to Sustain NAA/Cr Levels in the Dorsolateral Prefrontal Cortex Are Associated with Depressive Episode Recurrence under Maintenance Therapy: A Proton Magnetic Resonance Spectroscopy Retrospective Cohort Study

Frontiers in Psychiatry, 2017
BackgroundThe aim of this study was to evaluate the relationship between changes in proton magnetic resonance spectroscopy (1H-MRS) parameters at the start of the index episode recovery phase and at recurrence in patients with recurrent depression who ...
Neven Henigsberg, Helena Šarac, Marko Radoš, Marko Radoš, Milan Radoš, David Ozretić, David Ozretić, Tamara Foro, Viktorija Erdeljić Turk, Pero Hrabač, Maja Bajs Janović, Benedict Rak, Petra Kalember   +12 more
doaj   +1 more source

Adherence to a healthy lifestyle of the Russian population depending on the socio-demographics

Кардиоваскулярная терапия и профилактика, 2020
Aim. To assess the relationship of the population’s adherence to a healthy lifestyle (HLS) with socio-demographics and to carry out a comparative analysis of adherence according to ESSE-RF-1 and ESSE-RF-2 studies.Material and methods.
S. A. Shalnova, S. A. Maksimov, Yu. A. Balanova, S. E. Evstifeeva, A. E. Imaeva, А. V. Kapustina, N. S. Karamnova, G. A. Muromtseva, I. A. Viktorova, N. N. Prishchepa, A. N. Redko, S. S. Yakushin, O. M. Drapkina   +12 more
doaj   +1 more source

Psychological treatments in schizophrenia: I. Meta-analysis of family intervention and cognitive behaviour therapy

, 2002
Background. While there is a growing body of evidence on the efficacy of psychological interventions for schizophrenia, this meta-analysis improves upon previous systematic and meta-analytical reviews by including a wider range of randomized controlled ...
Pilling, S., Geddes, J., Morgan, C, Geddes, J, Kuipers, E, Bebbington, P., Garety, P, Morgan, C., Orbach, G., Garety, P., Bebbington, P, Garety, P; id_orcid, Pilling, S, Orbach, G, Kuipers, E; id_orcid, Kuipers, E.   +15 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Disease Burden and Healthcare Utilization Among Patients with Chronic Obstructive Pulmonary Disease (COPD) in England

International Journal of COPD, 2022
Leah B Sansbury,1 David A Lipson,2,3 Chanchal Bains,4 Glenn A Anley,5 Kieran J Rothnie,4 Afisi S Ismaila6,7 1Value Evidence and Outcomes, Epidemiology, R&D Global Medical, GlaxoSmithKline, Research Triangle Park, NC, USA; 2Respiratory Clinical Sciences ...
Sansbury LB, Lipson DA, Bains C, Anley GA, Rothnie KJ, Ismaila AS   +5 more
doaj  

Discontinuation of maintenance therapy against toxoplasma encephalitis in AIDS patients with sustained response to anti-retroviral therapy

, 2006
Discontinuation of maintenance therapy against toxoplasma encephalitis (TE) for individuals infected with human immunodeficiency virus (HIV) who are receiving successful anti-retroviral therapy is considered safe.
Christen, A, Opravil, M, Swiss, HIV Cohort Study, Christen, A., Bertschy, S, Schiffer, V, Schmid, P., Furrer, H, Furrer, H., Opravil, M., Cavassini, M., Schmid, P, Flepp, M, Cavassini, M, Bernasconi, E, Schiffer, V., Bertschy, S., Chave, J-P., Chave, JP, Flepp, M., Bernasconi, E.   +20 more
core   +1 more source

A retrospective comparative study of three data modelling techniques in anticoagulation therapy. [PDF]

, 2008
Three types of data modelling technique are applied retrospectively to individual patients’ anticoagulation therapy data to predict their future levels of anticoagulation.
Angelov, Plamen, Costas Xydeas, Xydeas, C., McDonald, Simon, Plamen Angelov, Simon McDonald   +5 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source