Results 41 to 50 of about 9,537,434 (312)
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
BackgroundThe JAVELIN Bladder 100 phase 3 trial demonstrated the efficacy and safety of avelumab administered as first-line (1L) maintenance treatment in patients with advanced urothelial carcinoma (UC) without disease progression after 1L platinum-based
Se Hoon Park +9 more
doaj +1 more source
Background and purpose: In recent years, drug therapies have played an increasing role in management of drug-related crimes due to decrease in efficacy of other anti-crime methods.
Arash Naghipour +4 more
doaj
Background Mantle cell lymphoma (MCL) is an uncommon heterogeneous subtype of B cell non‐Hodgkin lymphoma, and clinical features in MCL appear regional characteristics.
Ping Yang +19 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Maintenance treatment in multiple myeloma
Maintenance chemotherapy has failed to demonstrate any benefit [1, 2]. Corticosteroid maintenance was found to prolong the duration of response; however, the effect on survival was controversial [3, 4]. Interferon-a represented a great hope in the 1980s but metaanalysis of randomized trials showed a modest increase in progression-free survival (PFS ...
openaire +2 more sources
Testing the cognitive-behavioural maintenance models across DSM-5 bulimic-type eating disorder diagnostic groups: A multi-centre study [PDF]
The original cognitive-behavioural (CB) model of bulimia nervosa, which provided the basis for the widely used CB therapy, proposed that specific dysfunctional cognitions and behaviours maintain the disorder.
Zanetti, M. Assunta +17 more
core +1 more source
Parental functioning during maintenance treatment for childhood acute lymphoblastic leukemia:Effects of treatment intensity and dexamethasone pulses [PDF]
Background During maintenance treatment, Dutch pediatric patients with medium-risk (MR) acute lymphoblastic leukemia (ALL) receive intravenous chemotherapy and cyclic dexamethasone. Dexamethasone affects child's sleep and behavior.
Steur, Lindsay M. H. +24 more
core +2 more sources
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Comparison of Family Empowerment between Patients with Relapse and Patients with Sustained Maintenance Treatment [PDF]
Objective: The aim of this study was to compare family empowerment between the patients with relapse and the ones with sustained maintenance treatment among drug addicts in Tabriz.
Lila moghadam, Khalil Esmaillopour
doaj

