Results 21 to 30 of about 9,537,434 (312)

Patient and Physician Preferences for Acute Myeloid Leukemia Maintenance Treatments Following Hematopoietic Stem Cell Transplantation

Patient Preference and Adherence, 2023
Lalit Saini,1 James D Griffin,2 Bhavik J Pandya,3 Manasee V Shah,3 Mo Zhou,4 Hongbo Yang,4 Yan Song,4 Deborah A Marshall5 1London Health Sciences Centre, London, Ontario, Canada; 2Dana-Farber Cancer Institute, Boston, MA, USA; 3Astellas Pharma, Inc ...
Saini L, Griffin JD, Pandya BJ, Shah MV, Zhou M, Yang H, Song Y, Marshall DA   +7 more
doaj  

Rationale and design of a multicenter, randomized phase II trial of durvalumab with or without multitarget tyrosine kinase inhibitor as maintenance treatment in extensive‐stage small‐cell lung cancer patients (DURABLE study)

The Clinical Respiratory Journal, 2023
Introduction Durvalumab is a check‐point inhibitor against programmed death ligand‐1 (PD‐L1), and anlotinib is a new orally administered multitarget tyrosine kinase inhibitor (TKI). Both agents have been approved in China. Preclinical and clinical trials
Bo Zhang, Hua Zhong, Chunlei Shi, Zhiqiang Gao, Runbo Zhong, Aiqin Gu, Weimin Wang, Tianqing Chu, Liwen Xiong, Wei Zhang, Huimin Wang, Xueyan Zhang, Baohui Han   +12 more
doaj   +1 more source

Long-term survival in metastatic gastric cancer patient with Apatinib plus S-1 maintenance treatment following first-line chemotherapy—case report

Frontiers in Oncology
AimGastric cancer is the third leading cause of cancer-related mortality and the fifth most common cancer globally. In China, many patients are diagnosed at an advanced stage and cannot be operated on, so the prognosis is very poor.
Zhen Wang, Hao Li, Yue Guan, Mingshuang Wu, Manqing Hu, Chenchen Fang, Huaxing Wu, Maopeng Yang   +7 more
doaj   +1 more source

Survival outcomes of low-dose and high-dose bevacizumab front-line maintenance in advanced high-grade serous ovarian cancer: a propensity score-matched real-world study

Frontiers in Oncology
BackgroundThe optimal dose of bevacizumab for first-line maintenance therapy in advanced ovarian high-grade serous carcinoma (HGSC) remains controversial due to the lack of head-to-head RCTs. This real-world study aimed to compare the efficacy and safety
Tao Wu, Yahui Shen, Xiaowei Wang, Ruxing Xi, Lijuan Hu, Jianrong Lu, Guoqing Wang, Pengchuang Zhang   +7 more
doaj   +1 more source

FLUOXETINE IN THE MAINTENANCE TREATMENT OF ALCOHOL DEPENDENCY

Psychiatry and Clinical Psychopharmacology, 2021
Serotonin reuptake inhibitors have an impact on the craving behaviour in alcohol dependency. Moreover, they decrease the level of alcohol consumption when used as a part of a compound treatment program.
Zehra ARIKAN, Asli Kuruoglu, Behçet COŞAR, Nüket BELER, Selçuk ASLAN, Erdal IŞIK   +5 more
doaj  

Reversing chemoresistance in ovarian cancer: network pharmacology reveals how hydroxychloroquine/sulfasalazine duotherapy remodels tumor inflammatory–immune microenvironment

Frontiers in Immunology
IntroductionChemoresistance is a key contributor of ovarian cancer (OC) mortality. Clinical observations of extended survival in OC patients with rheumatic comorbidities following anti-rheumatic treatment suggest hydroxychloroquine (HCQ) and ...
Xin Hong, Xin Hong, Xin Wen, Xin Wen, Ting Zhang, Yihao Liu, Yihao Liu, Yu Ji, Yu Ji, Xiaoyan Shen   +9 more
doaj   +1 more source

The effects of concurrent prescription of benzodiazepines for people undergoing opioid maintenance treatment. Systematic review [PDF]

, 2016
Background In Opioid Maintenance Treatment patients receive long acting opioids as a substitute for heroin and other common illegally used opioids. People with opioid dependence are likely to experience elevated levels of anxiety and sleep disturbance ...
Ding, Yunpeng, Mosdøl, Annhild, Hov, Laila   +2 more
core   +1 more source

A network meta-analysis of efficacy and safety for first-line and maintenance therapies in patients with unresectable colorectal liver metastases

Frontiers in Pharmacology
Background: Evidence comparing the efficacy of different treatments for patients with unresectable colorectal liver metastases (CRLM) receiving first-line or maintenance therapy is sparse.
Yunlin Jiang, Yunlin Jiang, Taihang Shao, Mingye Zhao, Yahong Xue, Xueping Zheng   +5 more
doaj   +1 more source

Malmö Treatment Referral and Intervention Study—High 12-Month Retention Rates in Patients Referred from Syringe Exchange to Methadone or Buprenorphine/Naloxone Treatment

Frontiers in Psychiatry, 2017
BackgroundHeroin dependence is associated with high mortality. Opioid agonist treatment (OAT) with methadone or buprenorphine has strong evidence for treatment of this relapsing condition. In our setting, OAT has been associated with strict and demanding
Martin Bråbäck, Martin Bråbäck, Lars Ekström, Lars Ekström, Katja Troberg, Katja Troberg, Suzan Nilsson, Suzan Nilsson, Pernilla Isendahl, Pernilla Isendahl, Louise Brådvik, Anders Håkansson, Anders Håkansson   +12 more
doaj   +1 more source

Opioid maintenance treatment: trajectories in and out of treatment [PDF]

Nordic Journal of Psychiatry, 2019
Although efficacy studies of opioid maintenance treatment (OMT) have shown evidence of treatment benefits, there is still need for studies on its effectiveness in natural clinical processes. This study investigates the development in health, substance use and social conditions of those who applied for OMT, including those denied access or discharged ...
Bodil Monwell, Arne Gerdner
openaire   +2 more sources