Results 1 to 10 of about 1,203,058 (120)

The evolving role of PARP inhibitors in advanced ovarian cancer

Forum of Clinical Oncology, 2021
The field of ovarian cancer has been revolutionized with the use of poly (ADP-ribose) polymerase (PARP) inhibitors, which present greater inhibition effect in epithelial subtype due to high rates of homologous recombination deficiency.
Levva Sofia, Skolariki Aglaia, Sogka Eleni, Bokas Alexandros, Assi Avraam, Pispirigou Marianna K., Koliou Panagiotis   +6 more
doaj   +1 more source

Enhancing panic disorder treatment with mobile-aided case management: an exploratory study based on a 3-year cohort analysis

Frontiers in Psychiatry, 2023
BackgroundIndividuals with panic disorder frequently face ongoing symptoms, suboptimal treatment adherence, and increased relapse rates. Although mobile health interventions have shown promise in improving treatment outcomes for numerous mental health ...
Chan-hen Tsai, Chan-hen Tsai, Mesakh Christian, Feipei Lai, Feipei Lai   +4 more
doaj   +1 more source

Comparison of the Efficacy and Safety of PARP Inhibitors as a Monotherapy for Platinum-Sensitive Recurrent Ovarian Cancer: A Network Meta-Analysis

Frontiers in Oncology, 2021
BackgroundThe present COVID-19 pandemic has tended toward normality. To provide convenient, safe, and effective home treatment programs for patients with recurrent ovarian cancer (ROC), the clinical efficacy and safety of poly (ADP-ribose) polymerase ...
Hongmei Wang, Meng Wu, Haonan Liu, Hang Zhou, Yang Zhao, Yifan Geng, Bo Jiang, Kai Zhang, Bo Zhang, Zhengxiang Han, Xiuping Du   +10 more
doaj   +1 more source

Cetuximab Can Be an Effective and Low-Toxicity Maintenance Treatment Drug in Patients With Metastatic Colorectal Cancer: A Real-World Study of Zhejiang Cancer Hospital

Frontiers in Pharmacology, 2021
After initial treatment, maintenance therapy is now commonly used in mCRC patients, which can help patients live longer, have lower side effects, and higher quality of life.
Meiqin Yuan, Zeng Wang, Yazhen Zhao, Tingting Feng, Wangxia Lv, Haijun Zhong   +5 more
doaj   +1 more source

The Influence of an Attachment-Related Stimulus on Oxytocin Reactivity in Poly-Drug Users Undergoing Maintenance Therapy Compared to Healthy Controls

Frontiers in Psychiatry, 2020
BackgroundSubstance use disorders (SUDs) have been described as a dysfunctional way to compensate for deficiencies in that person’s underlying attachment system.
Jürgen Fuchshuber, Jürgen Fuchshuber, Jasmin Tatzer, Jasmin Tatzer, Michaela Hiebler-Ragger, Michaela Hiebler-Ragger, Florian Trinkl, Florian Trinkl, Andreas Kimmerle, Andreas Kimmerle, Anita Rinner, Anna Buchheim, Silke Schrom, Beate Rinner, Klaus Leber, Thomas Pieber, Elisabeth Weiss, Andrew J. Lewis, Hans-Peter Kapfhammer, Human Friedrich Unterrainer, Human Friedrich Unterrainer, Human Friedrich Unterrainer   +21 more
doaj   +1 more source

Recurrence of major depressive disorder following a switch from escitalopram to St. John’s Wort: a case report

Psychiatry and Clinical Psychopharmacology, 2021
Hypericum perforatum extracts, popularly known as St. John’s wort (known as “sarı kantaron” in Turkish) are widely used for the treatment of major depression, especially in German speaking countries.
Erhan Ertekin
doaj   +1 more source

Comparison of the risk of drop-out from opioid maintenance treatment in patients using naltrexone implants vs. oral buprenorphine-naloxone (tur)

Klinik Psikiyatri Dergisi, 2021
INTRODUCTION[|]Through increasing prevalence, opioid use disorder has been an important public health problem. The aim of this study is to compare the risk of drop-out from opioid use disorder maintenance treatment in patients using naltrexone implants ...
Umut Kırlı, Omer Nart
doaj   +1 more source

Diagnosis and treatment of mantle cell lymphoma

Swiss Medical Weekly, 2013
Mantle cell lymphoma (MCL) is a relatively rare lymphoma entity accounting for an estimated 3%–6% of all non-Hodgkin’s lymphoma cases. Characterised by both the incurability of indolent lymphomas and the rapid growth of aggressive lymphomas, MCL has
Felicitas Hitz, Mario Bargetzi, Sergio Cogliatti, Andreas Lohri, Christian Taverna, Christoph Renner, Ulrich Mey   +6 more
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Continuing posterior tibial nerve stimulation after twelve weekly sessions: a randomized controlled trial

Urogynaecologia International Journal, 2022
Posterior Tibial Nerve Stimulation (PTNS) is a treatment option for refractory Overactive Bladder (OAB). There is currently no evidence to support which maintenance schedule is most effective.
Jessica S. Zigman, Stephanie J. Handler, Stephanie Amaya, Aldene O. Zeno, Yoko Takashima, John J. Navas, Tajnoos Yazdany   +6 more
doaj   +1 more source

Cost-effectiveness of fuzuloparib compared to routine surveillance, niraparib and olaparib for maintenance treatment of patients with germline BRCA1/2 mutation and platinum-sensitive recurrent ovarian carcinoma in China

Frontiers in Pharmacology, 2023
Background: Maintenance therapy with the poly (ADP-ribose) polymerase inhibitors (PARPis) for platinum-sensitive recurrent ovarian carcinoma (OC) have proven to be effective compared with placebo.
Jing Nie, Huina Wu, Lei Sun, Yanjiao Ding, Yepeng Luan, Jiyong Wu   +5 more
doaj   +1 more source