, 1988 International audienceMaitotoxin, a potent marine toxin extracted from peredinians, was found to mimic fertilization in Xenopus oocytes and to trigger the breakdown of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2, the precursor of inositol 1,4,5 ...
Le Peuch, Christian +7 more
core +1 more source
Characterization of maitotoxin‐4 (MTX4) using electrospray positive mode ionization high‐resolution mass spectrometry and UV spectroscopy [PDF]
, 2020 Francesco Pisapia +6 more
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Lonspray mass spectrometry of ciguatoxin‐1, maitotoxin‐2 and ‐3, and related marine polyether toxins
, 1994 A range of marine polyether toxins from dinoflagellates were analysed by ionspray mass spectrometry. Ciguatoxin-1 ([M + H]+ m/z = 1,111.8) purified from several fish species yielded singly charged ions corresponding to the parent ion, sodium and H2O ...
Lewis, Richard J. +7 more
core +1 more source
Synthetic Study of the C’D’E’ Ring System of Maitotoxin via Furan Based Strategy
, 2021 Tohru Oishi +3 more
openalex +1 more source
, 2016 The stereoselective syntheses of the C‘D‘E‘F‘-ring system of maitotoxin and the FG-ring system of gambierol were accomplished. The key steps involve 6-endo-cyclization of methylepoxide, SmI2-induced reductive cyclization, 6-endo-cyclization of ...
Goh Matsuo (2702941) +3 more
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Folded Conformations of Maitotoxin
, 2008 "We used classical molecular mechanics and dynamicssimulations to sample the conformational space of maitotoxin, thelargest and most lethal natural product. Among the set of minimaobtained, the five conformers with the lowest energies show foldedstructures with an intramolecular hole.
Myrna H. Matus +2 more
openaire +1 more source
Maitotoxin stimulates hormonal release and calcium flux in rat anterior pituitary cells in vitro
, 1984 The marine dinoflagellate toxin maitotoxin (MTX), an activator of calcium channels, stimulates the release of prolactin (PRL), growth hormone (GH), thyroid-stimulating hormone (TSH), and luteinizing hormone (LH) from monolayers of anterior pituitary ...
K. Koike +6 more
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Polyketide synthesis genes associated with toxin production in two species of Gambierdiscus (Dinophyceae) [PDF]
, 2015 Background: Marine microbial protists, in particular, dinoflagellates, produce polyketide toxins with ecosystem-wide and human health impacts. Species of Gambierdiscus produce the polyether ladder compounds ciguatoxins and maitotoxins, which can lead to ...
Uwe John +37 more
core +1 more source
Synthesis-Driven Stereochemical Assignment of Marine Polycyclic Ether Natural Products. [PDF]
Mar Drugs, 2021 Fuwa H.
europepmc +1 more source
In vivo subchronic effects of ciguatoxin-related compounds, reevaluation of their toxicity. [PDF]
Arch Toxicol, 2022 Raposo-García S +9 more
europepmc +1 more source