Results 71 to 80 of about 811 (177)

Maitotoxin stimulates hormonal release and calcium flux in rat anterior pituitary cells in vitro

, 1984
The marine dinoflagellate toxin maitotoxin (MTX), an activator of calcium channels, stimulates the release of prolactin (PRL), growth hormone (GH), thyroid-stimulating hormone (TSH), and luteinizing hormone (LH) from monolayers of anterior pituitary ...
K. Koike, G. Schettini, M. J. Cronin, I. S. Login, A. M. Judd, T. Yasumoto, R. M. MacLeod   +6 more
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Polyketide synthesis genes associated with toxin production in two species of Gambierdiscus (Dinophyceae) [PDF]

, 2015
Background: Marine microbial protists, in particular, dinoflagellates, produce polyketide toxins with ecosystem-wide and human health impacts. Species of Gambierdiscus produce the polyether ladder compounds ciguatoxins and maitotoxins, which can lead to ...
Uwe John, Bolch, CJS, Shauna A. Murray, Harwood, D.T., John, Uwe, Rhodes, L., Lesley L. Rhodes, Kholi, Gurjeet, Figueroa, R.I., Groth, M, Christopher J. S. Bolch, Figueroa, Rosa, Figueroa, RI, Rhodes, Lesley L, Kohli, GS, John, U. (Uwe), Rosa I. Figueroa, Bolch, C., Harwood, D Tim, Kohli, Gurjeet S, D. Tim Harwood, Rhodes, LL, Kohli, Gurjeet, Murray, SA, Rhodes, L.L., Bolch, Christopher, Figueroa, Rosa Isabel, Bolch, Christopher J S, Harwood, DT, John, U, Groth, Marco, Murray, S.A., Gurjeet S. Kohli, Kholi, G. (Gurjeet), Groth, M., Marco Groth, Murray, Shauna A, Figueroa, R.I. (Rosa Isabel)   +37 more
core   +1 more source

In vivo subchronic effects of ciguatoxin-related compounds, reevaluation of their toxicity. [PDF]

Arch Toxicol, 2022
Raposo-García S, Boente-Juncal A, Rodriguez-Vieytes M, Camiña M, Costas C, Cao A, Louzao MC, Cifuentes M, Vale C, Botana LM.   +9 more
europepmc   +1 more source

Modulation by propranolol of the uptake of ethidium bromide by rat submandibular acinar cells exposed to a P2X(7) agonist or to maitotoxin.

, 2001
We have compared the formation of pores in rat submandibular acinar cells in response to 2',3'-O-(4-benzoylbenzoyl) adenosine 5'-triphosphate (Bz-ATP) and maitotoxin. Bz-ATP (100 microM) permeabilized the cells to ethidium bromide. The uptake of ethidium
Aida Marino, Pochet, Stéphanie, Elie Kabré, Chaib, Naima, Jean-Paul Dehaye, Naima Chaı̈b, Dehaye, Jean-Paul, Stéphanie Pochet, Kabre, Elie, Marino, Aida, Alzola, Eduardo, Eduardo Alzola   +11 more
core   +1 more source

Maitotoxin activates an endogenous non-selective cation channel and is an effective initiator of the activation of the heterologously expressed hTRPC-1 (transient receptor potential) non-selective cation channel in H4-IIE liver cells

, 2001
Copyright © 2001 Elsevier Science B.V. All rights reserved.The structures and mechanisms of activation of non-selective cation channels (NSCCs) are not well understood although NSCCs play important roles in the regulation of metabolism, ion transport ...
Rychkov, G., Grigori Rychkov, Barritt, G., Harland, M.Lyn, Gregory J Barritt, Brereton, Helen M, Brereton, H., Helen M Brereton, Chen, Jinglong, Chen, J., Barritt, Gregory J, Rychkov, Grigori, Jinglong Chen, M.Lyn Harland, Harland, M.   +14 more
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シジミガイ科貝類精子の先体に対するMaitotoxinの影響

, 1988
Departmental Bulletin PaperMaitotozin, isolated from a toxic marine dinoflagellate Gambierdiscus toxicus by Yasumoto et al., induced the exocytosis of the acrosomal vesicle in the Corbiculidae spermatozoa.
押谷, 美子, 東, 怜
core  

Purification and characterisation of large and small maitotoxins from cultured gambierdiscus toxicus

, 1994
Three strains of cultured Gambierdiscus toxicus yielded distinct maitotoxins (maitotoxin-1, -2, and -3) which were purified to homogeneity by high pressure liquid chromatography.
Lewis, Richard J., Holmes, Michael J., Richard J. Lewis, Michael J. Holmes   +3 more
core   +1 more source

The C2 domain of calpain 5 contributes to enzyme activation and membrane localization. [PDF]

Biochim Biophys Acta Mol Cell Res, 2021
Bondada V, Gal J, Mashburn C, Rodgers DW, Larochelle KE, Croall DE, Geddes JW.   +6 more
europepmc   +1 more source

Complete Relative Stereochemistry of Maitotoxin

, 2016
By addressing the relative stereochemistry of the four acyclic portions via organic synthesis, the complete relative stereochemistry of maitotoxin (MTX) has been established as 1B. The relative stereochemistry of the C.1−C.15 portion was elucidated via a
Hitoshi Oinuma (2997303), Wanjun Zheng (2997300), John A. DeMattei (2645836), Yoshito Kishi (505169), Jiang-Ping Wu (1686907), James J.-W. Duan (2123200), Laura R. Cook (2997297)   +6 more
core   +1 more source

A 15-Year Retrospective Review of Ciguatera in the Madeira Islands (North-East Atlantic, Portugal). [PDF]

Toxins (Basel), 2023
Costa PR, Churro C, Rodrigues SM, Frazão B, Barbosa M, Godinho L, Soliño L, Timóteo V, Gouveia N.   +8 more
europepmc   +1 more source