Results 51 to 60 of about 1,190 (207)
Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells [PDF]
, 1994 We investigated whether maitotoxin activates non-selective cation channels, as was recently proposed [Soergel, Yasumoto, Daly and Gusovsky (1992) Mol. Pharmacol. 41, 487-493].
Musgrave, I. F. +2 more
core +1 more source
Maitotoxin, a potent, general activator of phosphoinositide breakdown [PDF]
FEBS Letters, 1989 Maitotoxin (MTX), a potent marine toxin, elicits a calcium‐dependent activation of cells that can be inhibited by calcium channel blockers like nifedipine. MTX also stimulates phosphoinositide breakdown in smooth muscle cells, NCB‐20 cells and PC12 cells through a nifedipine‐insensitive mechanism.
Gusovsky, Fabian +2 more
openaire +2 more sources
Recent Trends in Marine Phycotoxins from Australian Coastal Waters
Marine Drugs, 2017 Phycotoxins, which are produced by harmful microalgae and bioaccumulate in the marine food web, are of growing concern for Australia. These harmful algae pose a threat to ecosystem and human health, as well as constraining the progress of aquaculture ...
Penelope Ajani +2 more
doaj +1 more source
NLRP3: A Novel Mediator in Cardiovascular Disease
Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018 Cardiovascular disease is a major cause of death worldwide. Inflammasome infiltration has been identified to play a central role in the pathological progression of certain cardiovascular diseases, such as vascular damage spanning atherosclerosis, aneurysm, or arteritis; ischemic heart disease; and other nonischemic heart diseases including diabetic ...
Wenyi Zhou +8 more
wiley +1 more source
Cell Death‐Associated Molecular‐Pattern Molecules: Inflammatory Signaling and Control
Mediators of Inflammation, Volume 2014, Issue 1, 2014., 2014 Apoptosis, necroptosis, and pyroptosis are different cellular death programs characterized in organs and tissues as consequence of microbes infection, cell stress, injury, and chemotherapeutics exposure. Dying and death cells release a variety of self‐proteins and bioactive chemicals originated from cytosol, nucleus, endoplasmic reticulum, and ...
Beatriz Sangiuliano +4 more
wiley +1 more source
Dopamine inhibits maitotoxin-stimulated pituitary 45Ca2+ efflux and prolactin release
, 1986 We examined the hypothesis that dopaminergic inhibition of prolactin release is coupled to modulation of cellular calcium flux. Dispersed female rat pituitary cells were prelabeled in 45Ca2+ and perifused to determine simultaneously fractional calcium ...
I. S. Login, A. M. Judd, R. M. MacLeod
core +1 more source
BioMed Research International, Volume 2013, Issue 1, 2013., 2013 Crohn′s disease is a complex disease in which genome, microbiome, and environment interact to produce the immunological background of the disease. Disease in childhood is more extensive and characterized by a rapid progression, leading to severe repercussions in the course of the disorder.
Annalisa Marcuzzi +7 more
wiley +1 more source
Journal of Cell Communication and Signaling, Volume 6, Issue 4, Page 191-204, December 2012., 2012 Abstract Exposure to cadmium results in disturbances in cell homeostasis in all living organisms. The first response to stress factors, including cadmium, is activation of signal transduction pathways that mobilize cell defense mechanisms. The aim of this review is a comparison between the signaling network triggered by Cd in plants and animals ...
Jagna Chmielowska‐Bąk, Joanna Deckert
wiley +1 more source
The Stereochemical Assignment and Conformational Analysis of the V/W-Ring Juncture of Maitotoxin
, 2016 The unambiguous stereochemical assignment of the V/W-ring juncture of maitotoxin, as shown in Figure , was accomplished using a two-step approach: (1) the synthesis of two diastereomeric models Me-A and Me-B and (2) the comparison of the NMR ...
Hitoshi Oinuma (2997303) +3 more
core +2 more sources
, 1997 Capillary zone electrophoresis with UV detection was applied to the rapid and efficient separation of an underivatized phycotoxin, maitotoxin, associated with ciguateric fish poisoning.
Bouaicha, N +3 more
core +1 more source