Results 41 to 50 of about 811 (177)

Dopamine inhibits maitotoxin-stimulated pituitary 45Ca2+ efflux and prolactin release

open access: yes, 1986
We examined the hypothesis that dopaminergic inhibition of prolactin release is coupled to modulation of cellular calcium flux. Dispersed female rat pituitary cells were prelabeled in 45Ca2+ and perifused to determine simultaneously fractional calcium ...
I. S. Login, A. M. Judd, R. M. MacLeod
core   +1 more source

A common response to common danger? Comparison of animal and plant signaling pathways involved in cadmium sensing

open access: yesJournal of Cell Communication and Signaling, Volume 6, Issue 4, Page 191-204, December 2012., 2012
Abstract Exposure to cadmium results in disturbances in cell homeostasis in all living organisms. The first response to stress factors, including cadmium, is activation of signal transduction pathways that mobilize cell defense mechanisms. The aim of this review is a comparison between the signaling network triggered by Cd in plants and animals ...
Jagna Chmielowska‐Bąk, Joanna Deckert
wiley   +1 more source

The Stereochemical Assignment and Conformational Analysis of the V/W-Ring Juncture of Maitotoxin

open access: yes, 2016
The unambiguous stereochemical assignment of the V/W-ring juncture of maitotoxin, as shown in Figure , was accomplished using a two-step approach:  (1) the synthesis of two diastereomeric models Me-A and Me-B and (2) the comparison of the NMR ...
Hitoshi Oinuma (2997303)   +3 more
core   +2 more sources

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 23, September 8, 2025.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

Modulating P2X7 Receptor Signaling during Rheumatoid Arthritis: New Therapeutic Approaches for Bisphosphonates

open access: yesJournal of Osteoporosis, Volume 2012, Issue 1, 2012., 2012
P2X7 receptor‐mediated purinergic signaling is a well‐known mechanism involved in bone remodeling. The P2X7 receptor has been implicated in the pathophysiology of various bone and cartilage diseases, including rheumatoid arthritis (RA), a widespread and complex chronic inflammatory disorder. The P2X7 receptor induces the release into the synovial fluid
Alberto Baroja-Mazo   +2 more
wiley   +1 more source

A new method for determination of maitotoxin by capillary zone electrophoresis with ultraviolet detection

open access: yes, 1997
Capillary zone electrophoresis with UV detection was applied to the rapid and efficient separation of an underivatized phycotoxin, maitotoxin, associated with ciguateric fish poisoning.
Bouaicha, N   +3 more
core   +1 more source

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the risks to human health associated with the proliferation of Ostreopsis spp. on the Basque coast

open access: yesFood Risk Assess Europe, Volume 3, Issue 2, April 2025.
Abstract In France, the presence of marine microalgae of the genus Ostreopsis has been identified repeatedly on the Mediterranean coast for several years, whereas on the French Basque coasts its presence is much more recent. In the summers of 2021 and 2022, major Ostreopsis flowering episodes were reported on the Basque coast, resulting in several ...
Rodolphe Lemée   +73 more
wiley   +1 more source

Role of the Inflammasome, IL‐1β, and IL‐18 in Bacterial Infections

open access: yesThe Scientific World Journal, Volume 11, Issue 1, Page 2037-2050, 2011., 2011
The inflammasome is an important innate immune pathway that regulates at least two host responses protective against infections: (1) secretion of the proinflammatory cytokines IL‐1β and IL‐18 and (2) induction of pyroptosis, a form of cell death. Inflammasomes, of which different types have been identified, are multiprotein complexes containing pattern
Manoranjan Sahoo   +4 more
wiley   +1 more source

Addressing the safety of new food sources and production systems

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 23, Issue 3, May 2024.
Abstract New food sources and production systems (NFPS) are garnering much attention, driven by international trade, changing consumer preferences, potential sustainability benefits, and innovations in climate‐resilient food production systems. However, NFPS can introduce new challenges for food safety agencies and food manufacturers.
Yong Quan Tan   +4 more
wiley   +1 more source

Maitotoxin-induced liver cell death involving loss of cell ATP following influx of calcium

open access: yes, 1989
Maitotoxin, one of the most potent marine toxins known, produced cell death in cultures of rat hepatocytes with a TD50 of 80 pm at 24 hr. The cell death, as indicated by a dose- and time-dependent leakage of lactate dehydrogenase (LDH), was also ...
Krishna, Gopal   +3 more
core   +1 more source

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