Pannexin1 is part of the pore forming unit of the P2X7 receptor death complex [PDF]
, 1922 The purinergic receptor P2X7 is part of a complex signaling mechanism participating in a variety of physiological and pathological processes. Depending on the activation scheme, P2X7 receptors in vivo are non-selective cation channels or form large pores
Locovei, Silviu +4 more
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Maitotoxin, a potent, general activator of phosphoinositide breakdown [PDF]
FEBS Letters, 1989 Maitotoxin (MTX), a potent marine toxin, elicits a calcium‐dependent activation of cells that can be inhibited by calcium channel blockers like nifedipine. MTX also stimulates phosphoinositide breakdown in smooth muscle cells, NCB‐20 cells and PC12 cells through a nifedipine‐insensitive mechanism.
Gusovsky, Fabian +2 more
openaire +2 more sources
The development of endo-selective epoxide-opening cascades in water [PDF]
, 2009 This tutorial review traces the development of endo-regioselective epoxide-opening reactions in water. Templated, water-promoted epoxide-opening cyclization reactions can offer rapid access to subunits of the ladder polyethers, a fascinating and complex ...
Byers, Jeffery A. +4 more
core +1 more source
Arachidonic acid inhibits the store-operated Ca2+ current in rat liver cells [PDF]
, 2005 Copyright © 2005 The Biochemical SocietyVasopressin and other phospholipase-C-coupled hormones induce oscillations (waves) of [Ca2+]cyt (cytoplasmic Ca2+ concentration) in liver cells.
Putney +39 more
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Recent Trends in Marine Phycotoxins from Australian Coastal Waters
Marine Drugs, 2017 Phycotoxins, which are produced by harmful microalgae and bioaccumulate in the marine food web, are of growing concern for Australia. These harmful algae pose a threat to ecosystem and human health, as well as constraining the progress of aquaculture ...
Penelope Ajani +2 more
doaj +1 more source
Characterization of a Strain of Fukuyoa paulensis (Dinophyceae) from the Western Mediterranean Sea [PDF]
, 2016 17 páginas, 8 figuras, 4 tablasA single cell of the dinoflagellate genus Fukuyoa was isolated from the island of Formentera (Balearic Islands, west Mediterranean Sea), cultured, and characterized by morphological and molecular methods and toxin analyses.
David, Helena +4 more
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NLRP3: A Novel Mediator in Cardiovascular Disease
Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018 Cardiovascular disease is a major cause of death worldwide. Inflammasome infiltration has been identified to play a central role in the pathological progression of certain cardiovascular diseases, such as vascular damage spanning atherosclerosis, aneurysm, or arteritis; ischemic heart disease; and other nonischemic heart diseases including diabetic ...
Wenyi Zhou +8 more
wiley +1 more source
Design and mechanistic insight into ultrafast calcium indicators for monitoring intracellular calcium dynamics. [PDF]
, 2016 Calmodulin-based genetically encoded fluorescent calcium indicators (GCaMP-s) are powerful tools of imaging calcium dynamics from cells to freely moving animals.
A Badura +37 more
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Cell Death‐Associated Molecular‐Pattern Molecules: Inflammatory Signaling and Control
Mediators of Inflammation, Volume 2014, Issue 1, 2014., 2014 Apoptosis, necroptosis, and pyroptosis are different cellular death programs characterized in organs and tissues as consequence of microbes infection, cell stress, injury, and chemotherapeutics exposure. Dying and death cells release a variety of self‐proteins and bioactive chemicals originated from cytosol, nucleus, endoplasmic reticulum, and ...
Beatriz Sangiuliano +4 more
wiley +1 more source
Role of calcium channels in heavy metal toxicity [PDF]
, 2013 Cellular membranes are basically impermeable to ions and have developed specific pathways (channels, transporters or pumps) to facilitate metal translocation.
Marchetti, Carla
core +2 more sources