Results 21 to 30 of about 1,584 (185)

New insights into maitotoxin action [PDF]

European Journal of Biochemistry, 1988
Maitotoxin (3 ng/mol) induced a massive uptake of 45Ca2+ into BC3H1 cells. This effect exhibits a lag phase of 3 min. Inositol diphosphate formation occurred concomittantly with the 45Ca2+ uptake but inositol monophosphate formation was found only after a 5‐min delay following toxin addition.
F, Sladeczek, B H, Schmidt, R, Alonso, L, Vian, A, Tep, T, Yasumoto, R N, Cory, J, Bockaert   +7 more
openaire   +2 more sources

Plesiomonas: A Review on Food Safety, Fish‐Borne Diseases, and Tilapia

The Scientific World Journal, Volume 2021, Issue 1, 2021., 2021
Fish and fish products are considered a fundamental part of the human diet due to their high nutritional value. Food‐borne diseases are considered a major public health challenge worldwide due to their incidence, associated mortality, and negative economic repercussions. Food safety is the guarantee that foods will not cause harm to the health of those
Alejandro De Jesús Cortés-Sánchez, Luis Daniel Espinosa-Chaurand, Mayra Díaz-Ramirez, Erika Torres-Ochoa, Jesus L. Romalde   +4 more
wiley   +1 more source

High Value Phycotoxins From the Dinoflagellate Prorocentrum

Frontiers in Marine Science, 2021
Marine dinoflagellates produce chemically diverse compounds, with a wide range of biological activity (antimicrobial, anticancer, treatment of neurodegenerative disease along with use as biomedical research tools).
Dolores Camacho-Muñoz, Radisti A. Praptiwi, Linda A. Lawton, Christine Edwards   +3 more
doaj   +1 more source

Synthesis of the ABCDEFG Ring System of Maitotoxin [PDF]

Journal of the American Chemical Society, 2010
Maitotoxin (1) continues to fascinate scientists not only because of its size and potent neurotoxicity but also due to its molecular architecture. To provide further support for its structure and facilitate fragment-based biological studies, we developed an efficient chemical synthesis of the ABCDEFG segment 3 of maitotoxin.
K C, Nicolaou, Robert J, Aversa, Jian, Jin, Fatima, Rivas   +3 more
openaire   +2 more sources

Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]

, 1993
Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J., Gratzl, Manfred, Mayerhofer, Artur, Rosenbusch, B., Rudolf, M., Sterzik, K.   +5 more
core   +1 more source

Synthesis of the C′D′E′F′ Domain of Maitotoxin [PDF]

Journal of the American Chemical Society, 2010
A devised biomimetic strategy toward the C'D'E'F' domain (6) of maitotoxin (1) led to hydroxy triepoxide 8 as a postulated polyepoxide precursor. However, all attempts to induce the desired cascade to form the targeted compound through a zip-type reaction under neutral or acidic conditions failed, prompting adoption of a linear stepwise approach to 6 ...
K C, Nicolaou, Jae Hong, Seo, Tsuyoshi, Nakamura, Robert J, Aversa   +3 more
openaire   +2 more sources

Evidence that Ca2+-release-activated Ca2+ channels in rat hepatocytes are required for the maintenance of hormone-induced Ca2+ oscillations [PDF]

, 2003
59 PORTLAND PLACE, LONDON, ENGLAND, W1N ...
Gregory, Roland Bruce, Barritt, Gregory John   +1 more
core   +1 more source

P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]

, 2008
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King, Bucheimer RE, Dai LJ, Dubyak GR, Egan TM, Inscho EW, King BF, Lazarowski ER, Lazarowski ER, Lehrmann H, Leipziger J, Li L, McCoy DE, North RA, Pelegrin P, Piper AS, Ralevic V, Schwiebert EM, Scott S.P. Wildman, Shirley DG, Taylor AL, Unwin RJ, Vekaria R, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wolff SC, Zhang Y   +29 more
core   +1 more source

Alternative method to detect compounds produced by Gambierdiscus spp.

Frontiers in Marine Science, 2014
Ciguatoxins (CTXs) and CTX precursors are produced by several Gambierdiscus spp. These polyether toxins are associated to ciguatera fish poisoning (CFP). In addition to CTX, maitotoxins (MTX) and gambierol are also produced by these dinoflagellates.
Jon Andoni Sánchez
doaj   +1 more source

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome [PDF]

, 2009
Inflammasomes activate caspase-1 for processing and secretion of the cytokines interleukin-1 beta (IL-1 beta) and IL-18. Cryopyrin/NALP3/NLRP3 is an essential component of inflammasomes triggered by microbial ligands, danger-associated molecular patterns
Mohamed Lamkanfi, James L. Mueller, Alberto C. Vitari, Shahram Misaghi, Anna Fedorova, Kurt Deshayes, Wyne P. Lee, Hal M. Hoffman, Vishva M. Dixit, Aguilar-Bryan, Ashcroft, Boyden, Cassel, Clement, Dostert, Duncan, Halle, Hamon, Hoffman, Hornung, Kanneganti, Kanneganti, Laliberte, Lamkanfi, Lamkanfi, Locovei, Ma, Mariathasan, Mariathasan, Martinon, Marty, Meyer, Miki, Miki, Pelegrin, Pelegrin, Perregaux, Riddle, Rosengren, Schott, Solle, Stoller, Sutterwala, Yvan-Charvet   +43 more
core   +2 more sources