Results 21 to 30 of about 811 (177)

Plesiomonas: A Review on Food Safety, Fish‐Borne Diseases, and Tilapia

open access: yesThe Scientific World Journal, Volume 2021, Issue 1, 2021., 2021
Fish and fish products are considered a fundamental part of the human diet due to their high nutritional value. Food‐borne diseases are considered a major public health challenge worldwide due to their incidence, associated mortality, and negative economic repercussions. Food safety is the guarantee that foods will not cause harm to the health of those
Alejandro De Jesús Cortés-Sánchez   +4 more
wiley   +1 more source

High Value Phycotoxins From the Dinoflagellate Prorocentrum

open access: yesFrontiers in Marine Science, 2021
Marine dinoflagellates produce chemically diverse compounds, with a wide range of biological activity (antimicrobial, anticancer, treatment of neurodegenerative disease along with use as biomedical research tools).
Dolores Camacho-Muñoz   +3 more
doaj   +1 more source

Synthesis of the ABCDEFG Ring System of Maitotoxin [PDF]

open access: yesJournal of the American Chemical Society, 2010
Maitotoxin (1) continues to fascinate scientists not only because of its size and potent neurotoxicity but also due to its molecular architecture. To provide further support for its structure and facilitate fragment-based biological studies, we developed an efficient chemical synthesis of the ABCDEFG segment 3 of maitotoxin.
K C, Nicolaou   +3 more
openaire   +2 more sources

Synthesis of the C′D′E′F′ Domain of Maitotoxin [PDF]

open access: yesJournal of the American Chemical Society, 2010
A devised biomimetic strategy toward the C'D'E'F' domain (6) of maitotoxin (1) led to hydroxy triepoxide 8 as a postulated polyepoxide precursor. However, all attempts to induce the desired cascade to form the targeted compound through a zip-type reaction under neutral or acidic conditions failed, prompting adoption of a linear stepwise approach to 6 ...
K C, Nicolaou   +3 more
openaire   +2 more sources

Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin

open access: yes, 2016
As the largest secondary metabolite to be discovered as of yet, the polyether marine neurotoxin maitotoxin constitutes a major structural and synthetic challenge.
Taiki Umezawa (2008570)   +9 more
core   +2 more sources

Synthesis of the ABCDEFG Ring System of Maitotoxin

open access: yes, 2016
Maitotoxin (1) continues to fascinate scientists not only because of its size and potent neurotoxicity but also due to its molecular architecture. To provide further support for its structure and facilitate fragment-based biological studies, we developed
Fatima Rivas (1883584)   +3 more
core   +2 more sources

Alternative method to detect compounds produced by Gambierdiscus spp.

open access: yesFrontiers in Marine Science, 2014
Ciguatoxins (CTXs) and CTX precursors are produced by several Gambierdiscus spp. These polyether toxins are associated to ciguatera fish poisoning (CFP). In addition to CTX, maitotoxins (MTX) and gambierol are also produced by these dinoflagellates.
Jon Andoni Sánchez
doaj   +1 more source

Complete Structure of Maitotoxin.

open access: yesJournal of Synthetic Organic Chemistry, Japan, 1997
Maitotoxin (MTX, 1) is the most toxic and largest non-biopolymer known to date. The complete structural determination of MTX including the absolute configuration has been achieved recently. The relative configurations of the four acyclic portions (C1-C15, C35-C39, C63-C68, and C134-C142) were elucidated by (1) the extensive configurational analysis ...
SASAKI, Makoto, MURATA, Michio
openaire   +3 more sources

Ladder-Shaped Ion Channel Ligands: Current State of Knowledge

open access: yesMarine Drugs, 2017
Ciguatoxins (CTX) and brevetoxins (BTX) are polycyclic ethereal compounds biosynthesized by the worldwide distributed planktonic and epibenthic dinoflagellates of Gambierdiscus and Karenia genera, correspondingly.
Yuri B. Shmukler, Denis A. Nikishin
doaj   +1 more source

Rapid Extraction and Identification of Maitotoxin and Ciguatoxin-Like Toxins from Caribbean and Pacific Gambierdiscus Using a New Functional Bioassay.

open access: yesPLoS ONE, 2016
BackgroundCiguatera is a circumtropical disease produced by polyether sodium channel toxins (ciguatoxins) that enter the marine food chain and accumulate in otherwise edible fish.
Richard J Lewis   +6 more
doaj   +1 more source

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