Results 31 to 40 of about 1,190 (207)

Synthesis of C-Oligosaccharides through Versatile C(sp³ )-H Glycosylation of Glycosides. [PDF]

Angew Chem Int Ed Engl, 2022
The palladium‐catalyzed C(sp3)−H glycosylation of glycosides is disclosed. This saccharide assembly by C(sp3)−H glycosylation featured excellent site‐ and stereoselectivity and enabled the efficient synthesis of diverse C‐disaccharides and C‐trisaccharides.
Wu J, Kopp A, Ackermann L.
europepmc   +2 more sources

Ionic selectivity and regulation of maitotoxin-activated nonselective cation channels in rat cardiac myocytes [PDF]

, 2003
Maitotoxin (MTX) reversibly activated a nonselective cation channel in ventricular rat myocytes, which had an ion selectivity sequence of K + > Rb+ > Cs+ > Na+ = Li+ > NMDG.
Randy Rizek
core   +3 more sources

The Formosalides: Structure Determination by Total Synthesis

Angewandte Chemie, Volume 133, Issue 1, Page 450-458, January 4, 2021., 2021
Total synthesis allowed the identification of the most likely stereostructure of the cytotoxic marine macrolides of the formosalide family (see structure) from eight possibilities. The successful route was based upon an inherently flexible blueprint that builds all stereogenic centers by strictly catalyst controlled transformations prior to formation ...
Saskia Schulthoff, James Y. Hamilton, Marc Heinrich, Yonghoon Kwon, Conny Wirtz, Alois Fürstner   +5 more
wiley   +2 more sources

Two‐pore channel 1 and Ca2+ release‐activated Ca2+ channels contribute to the acrosomal pH‐dependent intracellular Ca2+ increase in mouse sperm

The Journal of Physiology, Volume 601, Issue 14, Page 2935-2958, 15 July 2023., 2023
Abstract figure legend Amphipathic weak bases like CatSper blockers (B) diffuse across the sperm plasma membrane from a region of high concentration to one of low concentration (1). Inside the cell, these compounds are accumulated and protonated (BH+) into the acrosomal lumen (2).
Enrique I. Oliver, Martina Jabloñski, Mariano G. Buffone, Alberto Darszon   +3 more
wiley   +1 more source

Phytobioactive compounds as therapeutic agents for human diseases: A review

Food Science &Nutrition, Volume 11, Issue 6, Page 2500-2529, June 2023., 2023
Phytobioactive compounds are plant secondary metabolites and have remarkable therapeutic potential. Polyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants showed remarkable antioxidant, anticancer, cytotoxic, anti‐inflammatory, cardioprotective, hepatoprotective, immunomodulatory, neuroprotective, and antidiabetic ...
Muhammad Riaz, Ramsha Khalid, Muhammad Afzal, Fozia Anjum, Hina Fatima, Saadiya Zia, Ghulam Rasool, Chukwuebuka Egbuna, Andrew G. Mtewa, Chukwuemelie Zedech Uche, Muhammad Aamir Aslam   +10 more
wiley   +1 more source

Health benefits of microalgae and their microbiomes

Microbial Biotechnology, Volume 15, Issue 7, Page 1966-1983, July 2022., 2022
Microalgae may offer solutions to the societal challenge we face concerning the lack of antibiotics treating the growing level of antimicrobial resistant bacteria and fungi in clinical and industrial settings. While the vast majority of microalgae and their associated microbiota are unstudied, they may be a fascinating and rewarding source for novel ...
Ines Krohn, Simon Menanteau‐Ledouble, Gunhild Hageskal, Yekaterina Astafyeva, Pierre Jouannais, Jeppe Lund Nielsen, Massimo Pizzol, Alexander Wentzel, Wolfgang R. Streit   +8 more
wiley   +1 more source

Synthese von C‐Oligosacchariden via vielseitiger C(sp3)‐H‐Glykosylierung von Glykosiden

Angewandte Chemie, Volume 134, Issue 11, March 7, 2022., 2022
Die Palladium‐katalysierte C(sp3)‐H‐Glykosylierung von Glykosiden wird erschlossen. Diese Saccharid‐Assemblierungsstrategie durch die C(sp3)‐H‐Glykosylierung zeichnet sich durch eine ausgezeichnete Site‐ und Stereoselektivität aus und ermöglicht die effiziente Synthese verschiedener C‐Disacchariden und C‐Trisacchariden.
Jun Wu, Adelina Kopp, Lutz Ackermann
wiley   +1 more source

Critical Review and Conceptual and Quantitative Models for the Transfer and Depuration of Ciguatoxins in Fishes

Toxins, 2021
We review and develop conceptual models for the bio-transfer of ciguatoxins in food chains for Platypus Bay and the Great Barrier Reef on the east coast of Australia.
Michael J. Holmes, Bill Venables, Richard J. Lewis   +2 more
doaj   +1 more source

New insights into maitotoxin action [PDF]

European Journal of Biochemistry, 1988
Maitotoxin (3 ng/mol) induced a massive uptake of 45Ca2+ into BC3H1 cells. This effect exhibits a lag phase of 3 min. Inositol diphosphate formation occurred concomittantly with the 45Ca2+ uptake but inositol monophosphate formation was found only after a 5‐min delay following toxin addition.
F, Sladeczek, B H, Schmidt, R, Alonso, L, Vian, A, Tep, T, Yasumoto, R N, Cory, J, Bockaert   +7 more
openaire   +2 more sources

Plesiomonas: A Review on Food Safety, Fish‐Borne Diseases, and Tilapia

The Scientific World Journal, Volume 2021, Issue 1, 2021., 2021
Fish and fish products are considered a fundamental part of the human diet due to their high nutritional value. Food‐borne diseases are considered a major public health challenge worldwide due to their incidence, associated mortality, and negative economic repercussions. Food safety is the guarantee that foods will not cause harm to the health of those
Alejandro De Jesús Cortés-Sánchez, Luis Daniel Espinosa-Chaurand, Mayra Díaz-Ramirez, Erika Torres-Ochoa, Jesus L. Romalde   +4 more
wiley   +1 more source