Results 61 to 70 of about 811 (177)
, 2016 The stereoselective synthesis of the maitotoxin C′D′E′F′-ring system having a side chain has been accomplished through a convergent strategy. The key reactions include Horner-Wadsworth-Emmons coupling of the C′D′E′-ring and the side chain and subsequent ...
Tadashi Nakata (2103187) +3 more
core +2 more sources
Calcium is permeable through a maitotoxin-activated nonselective cation channel in mouse L cells
, 1996 The shellfish poison maitotoxin causes the irreversible opening of nonselective cation channels in mouse L cell fibroblasts, consistent with the action of this toxin in other cell types and the previously demonstrated existence of 28-pS voltage ...
M. Estacion, J. J. Gargus, H. B. Nguyen
core +1 more source
Synthetic Studies on Maitotoxin. 2. Stereoselective Synthesis of the WXYZA′-Ring System
, 2016 The stereoselective synthesis of the WXYZA′-ring system of maitotoxin has been accomplished via a linear synthetic approach, in which key reactions were SmI2-induced cyclization of β-alkoxyacrylate for the construction of the A′-, Y-, and X-rings and 6 ...
Tadashi Nakata (2103187) +3 more
core +1 more source
, 1990 Gambierdiscus toxicus strains isolated from Australia and French Polynesia were grown in modified f2 and f10 nutrient media and the cells extracted for ciguatoxin and maitotoxin.
Lewis, Richard J. +5 more
core +1 more source
, 1988 International audienceMaitotoxin, a potent marine toxin extracted from peredinians, was found to mimic fertilization in Xenopus oocytes and to trigger the breakdown of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2, the precursor of inositol 1,4,5 ...
Le Peuch, Christian +7 more
core +1 more source
Neurotoxic Syndromes in Marine Poisonings a Review
Iranian South Medical Journal, 2014 Background: Marine neurotoxins as of Marine biotoxins are natural toxins that produced mainly by dinoflagellates, diatoms and several species of invertebrates and fish.
Gholam Hossein Mohebbi +2 more
doaj
Lonspray mass spectrometry of ciguatoxin‐1, maitotoxin‐2 and ‐3, and related marine polyether toxins
, 1994 A range of marine polyether toxins from dinoflagellates were analysed by ionspray mass spectrometry. Ciguatoxin-1 ([M + H]+ m/z = 1,111.8) purified from several fish species yielded singly charged ions corresponding to the parent ion, sodium and H2O ...
Lewis, Richard J. +7 more
core +1 more source
, 2016 The stereoselective syntheses of the C‘D‘E‘F‘-ring system of maitotoxin and the FG-ring system of gambierol were accomplished. The key steps involve 6-endo-cyclization of methylepoxide, SmI2-induced reductive cyclization, 6-endo-cyclization of ...
Goh Matsuo (2702941) +3 more
core +1 more source
Folded Conformations of Maitotoxin
, 2008 "We used classical molecular mechanics and dynamicssimulations to sample the conformational space of maitotoxin, thelargest and most lethal natural product. Among the set of minimaobtained, the five conformers with the lowest energies show foldedstructures with an intramolecular hole.
Myrna H. Matus +2 more
openaire +1 more source
Synthesis-Driven Stereochemical Assignment of Marine Polycyclic Ether Natural Products. [PDF]
Mar Drugs, 2021 Fuwa H.
europepmc +1 more source