Synthese von C‐Oligosacchariden via vielseitiger C(sp3)‐H‐Glykosylierung von Glykosiden
Angewandte Chemie, Volume 134, Issue 11, March 7, 2022., 2022 Die Palladium‐katalysierte C(sp3)‐H‐Glykosylierung von Glykosiden wird erschlossen. Diese Saccharid‐Assemblierungsstrategie durch die C(sp3)‐H‐Glykosylierung zeichnet sich durch eine ausgezeichnete Site‐ und Stereoselektivität aus und ermöglicht die effiziente Synthese verschiedener C‐Disacchariden und C‐Trisacchariden.
Jun Wu, Adelina Kopp, Lutz Ackermann
wiley +1 more source
Synthesis of C‐Oligosaccharides through Versatile C(sp3)−H Glycosylation of Glycosides
Angewandte Chemie International Edition, Volume 61, Issue 11, March 7, 2022., 2022 The palladium‐catalyzed C(sp3)−H glycosylation of glycosides is disclosed. This saccharide assembly by C(sp3)−H glycosylation featured excellent site‐ and stereoselectivity and enabled the efficient synthesis of diverse C‐disaccharides and C‐trisaccharides.
Jun Wu, Adelina Kopp, Lutz Ackermann
wiley +1 more source
Plesiomonas: A Review on Food Safety, Fish‐Borne Diseases, and Tilapia
The Scientific World Journal, Volume 2021, Issue 1, 2021., 2021 Fish and fish products are considered a fundamental part of the human diet due to their high nutritional value. Food‐borne diseases are considered a major public health challenge worldwide due to their incidence, associated mortality, and negative economic repercussions. Food safety is the guarantee that foods will not cause harm to the health of those
Alejandro De Jesús Cortés-Sánchez +4 more
wiley +1 more source
The role of 44-methylgambierone in ciguatera fish poisoning: Acute toxicity, production by marine microalgae and its potential as a biomarker for Gambierdiscus spp. [PDF]
, 2020 Ciguatera fish poisoning (CFP) is prevalent around the tropical and sub-tropical latitudes of the world and impacts many Pacific island communities intrinsically linked to the reef system for sustenance and trade.
Doblin MA +12 more
core +1 more source
Complete Structure of Maitotoxin.
Journal of Synthetic Organic Chemistry, Japan, 1997 Maitotoxin (MTX, 1) is the most toxic and largest non-biopolymer known to date. The complete structural determination of MTX including the absolute configuration has been achieved recently. The relative configurations of the four acyclic portions (C1-C15, C35-C39, C63-C68, and C134-C142) were elucidated by (1) the extensive configurational analysis ...
Makoto SASAKI, Michio MURATA
openaire +3 more sources
Polyketide synthesis genes associated with toxin production in two species of Gambierdiscus (Dinophyceae). [PDF]
BMC Genomics, 2015 Background Marine microbial protists, in particular, dinoflagellates, produce polyketide toxins with ecosystem-wide and human health impacts. Species of Gambierdiscus produce the polyether ladder compounds ciguatoxins and maitotoxins, which can lead to ...
Kohli GS +7 more
europepmc +5 more sources
Transcriptomic analysis of polyketide synthases in a highly ciguatoxic dinoflagellate, Gambierdiscus polynesiensis and low toxicity Gambierdiscus pacificus, from French Polynesia. [PDF]
, 2020 Marine dinoflagellates produce a diversity of polyketide toxins that are accumulated in marine food webs and are responsible for a variety of seafood poisonings.
Anderson, Paul E +5 more
core +2 more sources
Ciguatera mini review: 21st century environmental challenges and the interdisciplinary research efforts rising to meet them [PDF]
, 2021 Globally, the livelihoods of over a billion people are affected by changes to marine eco-systems, both structurally and systematically. Resources and ecosystem services, provided by the marine environment, contribute nutrition, income, and health ...
Bodi D. +5 more
core +1 more source
Chemodiversity of Ladder-Frame Prymnesin Polyethers in Prymnesium parvum [PDF]
, 2016 Blooms of the microalga Prymnesium parvum cause devastating fish kills worldwide, which are suspected to be caused by the supersized ladder-frame polyether toxins prymnesin-1 and -2. These toxins have, however, only been detected from P.
Andersen, Nikolaj Gedsted +7 more
core +3 more sources
The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro [PDF]
, 2006 Brevetoxins (PbTxs) are highly potent trans-syn polyether neurotoxins produced during blooms of several species of marine dinoflagellates, most notably Karenia brevis. These neurotoxins act on voltage-sensitive sodium channels prolonging the active state.
A.J. Bourdelais +30 more
core +1 more source