Results 11 to 20 of about 267 (149)

Alternative method to detect compounds produced by Gambierdiscus spp.

Frontiers in Marine Science, 2014
Ciguatoxins (CTXs) and CTX precursors are produced by several Gambierdiscus spp. These polyether toxins are associated to ciguatera fish poisoning (CFP). In addition to CTX, maitotoxins (MTX) and gambierol are also produced by these dinoflagellates.
Jon Andoni Sánchez
doaj   +2 more sources

Toxicology of Gambierdiscus spp. (Dinophyceae) from Tropical and Temperate Australian Waters. [PDF]

Mar Drugs, 2018
Ciguatera Fish Poisoning (CFP) is a human illness caused by the consumption of marine fish contaminated with ciguatoxins (CTX) and possibly maitotoxins (MTX), produced by species from the benthic dinoflagellate genus Gambierdiscus.
Larsson ME, Laczka OF, Harwood DT, Lewis RJ, Himaya SWA, Murray SA, Doblin MA.   +6 more
europepmc   +2 more sources

Detection of marine toxins using cell-based assays and Characterization of toxin profiles in ciguatera-related natural samples: microalgae and fish. / (Detección de toxinas marinas mediante ensayos celulares y Caracterización del perfil toxinico en muestras naturales asociadas a la ciguatera: microalgas y pescado [PDF]

, 2011
[eng] The suitability of neuroblastoma cell-based assays (Neuro-2a CBAs) was examined in order to characterize toxin profiles in ciguatera-related natural samples: microlagae (Gambierdiscus spp.
Caillaud, Amandine
core   +7 more sources

The Formosalides: Structure Determination by Total Synthesis

Angewandte Chemie, Volume 133, Issue 1, Page 450-458, January 4, 2021., 2021
Total synthesis allowed the identification of the most likely stereostructure of the cytotoxic marine macrolides of the formosalide family (see structure) from eight possibilities. The successful route was based upon an inherently flexible blueprint that builds all stereogenic centers by strictly catalyst controlled transformations prior to formation ...
Saskia Schulthoff, James Y. Hamilton, Marc Heinrich, Yonghoon Kwon, Conny Wirtz, Alois Fürstner   +5 more
wiley   +2 more sources

Two‐pore channel 1 and Ca2+ release‐activated Ca2+ channels contribute to the acrosomal pH‐dependent intracellular Ca2+ increase in mouse sperm

The Journal of Physiology, Volume 601, Issue 14, Page 2935-2958, 15 July 2023., 2023
Abstract figure legend Amphipathic weak bases like CatSper blockers (B) diffuse across the sperm plasma membrane from a region of high concentration to one of low concentration (1). Inside the cell, these compounds are accumulated and protonated (BH+) into the acrosomal lumen (2).
Enrique I. Oliver, Martina Jabloñski, Mariano G. Buffone, Alberto Darszon   +3 more
wiley   +1 more source

Maitotoxin: An Inspiration for Synthesis [PDF]

Israel Journal of Chemistry, 2011
AbstractMaitotoxin holds a special place in the annals of natural products chemistry as the largest and most toxic secondary metabolite known to date. Its fascinating, ladder‐like, polyether molecular structure and diverse spectrum of biological activities elicited keen interest from chemists and biologists, who recognized its uniqueness and potential ...
K C, Nicolaou, Robert J, Aversa
openaire   +2 more sources

Phytobioactive compounds as therapeutic agents for human diseases: A review

Food Science &Nutrition, Volume 11, Issue 6, Page 2500-2529, June 2023., 2023
Phytobioactive compounds are plant secondary metabolites and have remarkable therapeutic potential. Polyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants showed remarkable antioxidant, anticancer, cytotoxic, anti‐inflammatory, cardioprotective, hepatoprotective, immunomodulatory, neuroprotective, and antidiabetic ...
Muhammad Riaz, Ramsha Khalid, Muhammad Afzal, Fozia Anjum, Hina Fatima, Saadiya Zia, Ghulam Rasool, Chukwuebuka Egbuna, Andrew G. Mtewa, Chukwuemelie Zedech Uche, Muhammad Aamir Aslam   +10 more
wiley   +1 more source

Health benefits of microalgae and their microbiomes

Microbial Biotechnology, Volume 15, Issue 7, Page 1966-1983, July 2022., 2022
Microalgae may offer solutions to the societal challenge we face concerning the lack of antibiotics treating the growing level of antimicrobial resistant bacteria and fungi in clinical and industrial settings. While the vast majority of microalgae and their associated microbiota are unstudied, they may be a fascinating and rewarding source for novel ...
Ines Krohn, Simon Menanteau‐Ledouble, Gunhild Hageskal, Yekaterina Astafyeva, Pierre Jouannais, Jeppe Lund Nielsen, Massimo Pizzol, Alexander Wentzel, Wolfgang R. Streit   +8 more
wiley   +1 more source

Synthese von C‐Oligosacchariden via vielseitiger C(sp3)‐H‐Glykosylierung von Glykosiden

Angewandte Chemie, Volume 134, Issue 11, March 7, 2022., 2022
Die Palladium‐katalysierte C(sp3)‐H‐Glykosylierung von Glykosiden wird erschlossen. Diese Saccharid‐Assemblierungsstrategie durch die C(sp3)‐H‐Glykosylierung zeichnet sich durch eine ausgezeichnete Site‐ und Stereoselektivität aus und ermöglicht die effiziente Synthese verschiedener C‐Disacchariden und C‐Trisacchariden.
Jun Wu, Adelina Kopp, Lutz Ackermann
wiley   +1 more source

Synthesis of C‐Oligosaccharides through Versatile C(sp3)−H Glycosylation of Glycosides

Angewandte Chemie International Edition, Volume 61, Issue 11, March 7, 2022., 2022
The palladium‐catalyzed C(sp3)−H glycosylation of glycosides is disclosed. This saccharide assembly by C(sp3)−H glycosylation featured excellent site‐ and stereoselectivity and enabled the efficient synthesis of diverse C‐disaccharides and C‐trisaccharides.
Jun Wu, Adelina Kopp, Lutz Ackermann
wiley   +1 more source