Results 31 to 40 of about 298,105 (317)

Physiological Characteristic Changes and Transcriptome Analysis of Maize (Zea mays L.) Roots under Drought Stress

International Journal of Genomics
Water deficit is a key limiting factor for limiting yield in maize (Zea mays L.). It is crucial to elucidate the molecular regulatory networks of stress tolerance for genetic enhancement of drought tolerance.
Chenglin Zou, Hua Tan, Kaijian Huang, Ruining Zhai, Meng Yang, Aihua Huang, Xinxing Wei, Runxiu Mo, Faqian Xiong   +8 more
doaj   +1 more source

Genome wide association analysis for yield related traits in maize

BMC Plant Biology, 2022
Background Understanding the genetic basis of yield related traits contributes to the improvement of grain yield in maize. Results Using 291 excellent maize inbred lines as materials, six yield related traits of maize, including grain yield per plant ...
Tingru Zeng, Zhaodong Meng, Runqing Yue, Shouping Lu, Wenlan Li, Wencai Li, Hong Meng, Qi Sun   +7 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Weediness and grain yield of specialty maize hybrids cultivated with the application of ecological fertilisers [PDF]

Selekcija i Semenarstvo, 2018
Maize hybrids (Zea mays L.) with specific traits, such as those with red pericarp, high-protein flints or white kernel hybrids, have increased utility value as they contain some vitamins and minerals beneficial to human and animal nutrition. Furthermore,
Simić Milena, Dragičević Vesna, Brankov Milan, Vančetović Jelena, Filipović Milomir, Srdić Jelena   +5 more
doaj  

Evaluation of saline tolerance at the seedling stage of various maize cross combinations

Vietnam Journal of Science, Technology and Engineering, 2017
This study was conducted at the Maize Research Institute of Vietnam using 24 maize hybrids, identified as STM1 to STM24, at five different salt concentrations, which were 0, 50, 100, 150, and 200 mM NaCl.
Huu Hung Nguyen, Van Vang Luong, Thi Minh Tam Ngo, Hoai Son Vu, Xuan Thang Nguyen   +4 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Genetic gains in early maturing maize hybrids developed by the International Maize and Wheat Improvement Center in Southern Africa during 2000–2018

Frontiers in Plant Science
Genetic gain estimation in a breeding program provides an opportunity to monitor breeding efficiency and genetic progress over a specific period. The present study was conducted to (i) assess the genetic gains in grain yield of the early maturing maize ...
Amsal Tarekegne, Dagne Wegary, Jill E. Cairns, Mainassara Zaman-Allah, Yoseph Beyene, Demewoz Negera, Adefris Teklewold, Kindie Tesfaye, MacDonald B. Jumbo, Biswanath Das, Egas J. Nhamucho, Kelvin Simpasa, Kesbell K. E. Kaonga, Kingstone Mashingaidze, Ndhlela Thokozile, Xavier Mhike, Boddupalli M. Prasanna   +16 more
doaj   +1 more source

Comparative analysis of mitochondrial genomes of maize CMS-S subtypes provides new insights into male sterility stability

BMC Plant Biology, 2022
Background Cytoplasmic male sterility (CMS) is a trait of economic importance in the production of hybrid seeds. In CMS-S maize, exerted anthers appear frequently in florets of field-grown female populations where only complete male-sterile plants were ...
Senlin Xiao, Jingfeng Xing, Tiange Nie, Aiguo Su, Ruyang Zhang, Yanxin Zhao, Wei Song, Jiuran Zhao   +7 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source