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Neurobiology of Major Depressive Disorder [PDF]

open access: yesNeural Plasticity, 2013
We survey studies which relate abnormal neurogenesis to major depressive disorder. Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling ...
Rosa Villanueva
doaj   +3 more sources

Lipidomics in Major Depressive Disorder [PDF]

open access: yesFrontiers in Psychiatry, 2018
Omic sciences coupled with novel computational approaches such as machine intelligence offer completely new approaches to major depressive disorder (MDD) research.
Andreas Walther   +7 more
doaj   +3 more sources

Medicinal Plants for Major Depressive Disorder [PDF]

open access: yesBrain Sciences
Major Depressive Disorder (MDD) is a severe, chronic illness for which conventional treatments often show limited efficacy and side effects, driving a renewed interest in traditional medicinal plants. The therapeutic promise of these plants lies in their
Amanda Gollo Bertollo   +4 more
doaj   +2 more sources

Affective Priming in Major Depressive Disorder [PDF]

open access: yesFrontiers in Integrative Neuroscience, 2012
Research on cognitive biases in depression has provided considerable evidence for the impact of emotion on cognition. Individuals with depression tend to preferentially process mood-congruent material and to show deficits in the processing of positive ...
Joelle eLeMoult   +3 more
doaj   +3 more sources

Major Depressive Disorder

open access: yesSouth African Journal of Psychiatry, 2013
The treatment guideline draws on several international guidelines: (i)Practice Guidelines of the American Psychiatric Association (APA)for the Treatment of Patients with Major Depressive Disorder, SecondEdition;[1](ii) Clinical Guidelines for the ...
G Grobler
doaj   +2 more sources

Major depressive disorder [PDF]

open access: yesNature Reviews Disease Primers, 2016
Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.
Otte, Christian   +7 more
openaire   +5 more sources

Perfectionism in Major Depressive Disorder [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2020
Perfectionism is individuals setting hard-to-reach goals for themselves or others and striving to achieve them. People have difficulties in their lives because of their perfectionist thinking.
Gülen Say
doaj   +1 more source

Major Depressive Disorder [PDF]

open access: yesNeuron, 2000
In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Fava, Maurizio, Kendler, Kenneth S
openaire   +2 more sources

Efficacy of Ketamine as an Adjuvant to Antidepressants in the Treatment of Depression [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: Depression is the second leading cause of morbidity worldwide. Currently, available antidepressants mostly target the monoamine system. The onset of action and response rates for these antidepressants are varied.
Hrishikesh Solunke   +4 more
doaj   +1 more source

Ketamine: A New Antidepressant? [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2015
Standart antidepressants are needed for the many individuals with major depressive disorder. However they do not respond adequately to treatment and because of a delay of weeks before the emergence of therapeutic effects.
Feride Karacaer
doaj   +1 more source

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